A secretory kinase complex regulates extracellular protein phosphorylation
about
Amelogenesis imperfecta caused by N-terminal enamelin point mutations in mice and men is driven by endoplasmic reticulum stress.Structure of Fam20A reveals a pseudokinase featuring a unique disulfide pattern and inverted ATP-bindingFAM20A Gene Mutation: Amelogenesis or Ectopic Mineralization?Specific ablation of mouse Fam20C in cells expressing type I collagen leads to skeletal defects and hypophosphatemia.The evolving world of pseudoenzymes: proteins, prejudice and zombiesWhat is the point of pseudokinases?The dentin phosphoprotein repeat region and inherited defects of dentin.Systemic Control of Bone Homeostasis by FGF23 Signaling.FAM20A binds to and regulates FAM20C localizationPhosphorylation of spore coat proteins by a family of atypical protein kinases.Loss of epithelial FAM20A in mice causes amelogenesis imperfecta, tooth eruption delay and gingival overgrowthInactivation of Fam20B in Joint Cartilage Leads to Chondrosarcoma and Postnatal Ossification Defects.Structure of protein O-mannose kinase reveals a unique active site architecture.Systematic network-based discovery of a Fam20C inhibitor (FL-1607) with apoptosis modulation in triple-negative breast cancer.Nucleotide-binding mechanisms in pseudokinases.Fam20C is under the control of sphingolipid signaling in human cell lines.High-yield secretion of recombinant proteins from the microalga Chlamydomonas reinhardtii.Amelogenesis Imperfecta; Genes, Proteins, and Pathways.Extracellular phosphorylation of a receptor tyrosine kinase controls synaptic localization of NMDA receptors and regulates pathological pain.Phosphorylation of serine96 of histidine-rich calcium-binding protein by the Fam20C kinase functions to prevent cardiac arrhythmia.A distinctive oral phenotype points to FAM20A mutations not identified by Sanger sequencing.Inactivation of Fam20B in the dental epithelium of mice leads to supernumerary incisors.The interplay between extracellular matrix remodelling and kinase signalling in cancer progression and metastasis.The importance of a potential phosphorylation site in enamelin on enamel formation.Characterization of Ligand Binding to Pseudokinases Using a Thermal Shift Assay.Periodontal disease and FAM20A mutations.Vertebrate Lonesome Kinase Regulated Extracellular Matrix Protein Phosphorylation, Cell Shape, and Adhesion in Trabecular Meshwork Cells.Phosphoproteomic insights into processes influenced by the kinase-like protein DIA1/C3orf58.Structure and evolution of the Fam20 kinases.Inhibitor-induced HER2-HER3 heterodimerisation promotes proliferation through a novel dimer interface.Secretory kinase Fam20C tunes endoplasmic reticulum redox state via phosphorylation of Ero1α.
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P2860
A secretory kinase complex regulates extracellular protein phosphorylation
description
2015 nî lūn-bûn
@nan
2015 թուականին հրատարակուած գիտական յօդուած
@hyw
2015 թվականին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
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name
A secretory kinase complex regulates extracellular protein phosphorylation
@ast
A secretory kinase complex regulates extracellular protein phosphorylation
@en
A secretory kinase complex regulates extracellular protein phosphorylation
@en-gb
A secretory kinase complex regulates extracellular protein phosphorylation
@nl
type
label
A secretory kinase complex regulates extracellular protein phosphorylation
@ast
A secretory kinase complex regulates extracellular protein phosphorylation
@en
A secretory kinase complex regulates extracellular protein phosphorylation
@en-gb
A secretory kinase complex regulates extracellular protein phosphorylation
@nl
prefLabel
A secretory kinase complex regulates extracellular protein phosphorylation
@ast
A secretory kinase complex regulates extracellular protein phosphorylation
@en
A secretory kinase complex regulates extracellular protein phosphorylation
@en-gb
A secretory kinase complex regulates extracellular protein phosphorylation
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
A secretory kinase complex regulates extracellular protein phosphorylation
@en
P2093
Jack E Dixon
Jianzhong Wen
Junyu Xiao
Meghdad Rahdar
Vincent S Tagliabracci
P2860
P304
P3181
P356
10.7554/ELIFE.06120
P407
P577
2015-01-01T00:00:00Z