Mutations in LRRK2 increase phosphorylation of peroxiredoxin 3 exacerbating oxidative stress-induced neuronal death
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MAP1B rescues LRRK2 mutant-mediated cytotoxicityThe role of oxidative stress in Parkinson's diseaseAn early endosome regulator, Rab5b, is an LRRK2 kinase substrateThiol peroxidases ameliorate LRRK2 mutant-induced mitochondrial and dopaminergic neuronal degeneration in DrosophilaParkinson's Disease: The Mitochondria-Iron LinkCurrent understanding of LRRK2 in Parkinson's disease: biochemical and structural features and inhibitor designThe role of the LRRK2 gene in ParkinsonismProgressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in miceLeucine-rich repeat kinase 2 (LRRK2)-deficient rats exhibit renal tubule injury and perturbations in metabolic and immunological homeostasisA visual review of the interactome of LRRK2: Using deep-curated molecular interaction data to represent biology.Lrrk2 R1628P variant is a risk factor for essential tremorEvaluating LRRK2 genetic variants with unclear pathogenicity.Thiol redox homeostasis in neurodegenerative diseaseThe roles of redox enzymes in Parkinson's disease: Focus on glutaredoxin.Antioxidants inhibit neuronal toxicity in Parkinson's disease-linked LRRK2Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21(WAF1/CIP1) expressionThiol-redox signaling, dopaminergic cell death, and Parkinson's diseaseRegulation of PRDX1 peroxidase activity by Pin1.Decoding Parkinson's Disease Pathogenesis: The Role of Deregulated mRNA Translation.Effects of different doses of doxepin on passive avoidance learning in rats.LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: reversal by gene correction.Genetic insights into sporadic Parkinson's disease pathogenesis.2-cys peroxiredoxins: emerging hubs determining redox dependency of Mammalian signaling networks.The bad, the good, and the ugly about oxidative stress.Targeting leucine-rich repeat kinase 2 in Parkinson's disease.The interplay between iron accumulation, mitochondrial dysfunction, and inflammation during the execution step of neurodegenerative disorders.LRRK2, a puzzling protein: insights into Parkinson's disease pathogenesisThe prion hypothesis of Parkinson's disease.Cellular processes associated with LRRK2 function and dysfunctionLRRK2 at the Crossroad Between Autophagy and Microtubule Trafficking: Insights into Parkinson's Disease.Molecular changes in the postmortem parkinsonian brain.Thiopurines induce oxidative stress in T-lymphocytes: a proteomic approach.Effect of quercetin and its glucuronide metabolite upon 6-hydroxydopamine-induced oxidative damage in Neuro-2a cells.Morphological changes and altered expression of antioxidant proteins in a heterozygous dynein mutant; a mouse model of spinal muscular atrophy.Molecular mechanisms of OLIG2 transcription factor in brain cancer.Neuroprotective Effect of the LRRK2 Kinase Inhibitor PF-06447475 in Human Nerve-Like Differentiated Cells Exposed to Oxidative Stress Stimuli: Implications for Parkinson's Disease.The majority of newly generated cells in the adult mouse substantia nigra express low levels of Doublecortin, but their proliferation is unaffected by 6-OHDA-induced nigral lesion or Minocycline-mediated inhibition of neuroinflammation.Linking a genome-wide association study signal to a LRRK2 coding variant in Parkinson's disease.Ehrlichia chaffeensis TRP75 Interacts with Host Cell Targets Involved in Homeostasis, Cytoskeleton Organization, and Apoptosis Regulation To Promote Infection.The Sources of Reactive Oxygen Species and Its Possible Role in the Pathogenesis of Parkinson's Disease
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P2860
Mutations in LRRK2 increase phosphorylation of peroxiredoxin 3 exacerbating oxidative stress-induced neuronal death
description
2011 nî lūn-bûn
@nan
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
Mutations in LRRK2 increase ph ...... stress-induced neuronal death
@ast
Mutations in LRRK2 increase ph ...... stress-induced neuronal death
@en
Mutations in LRRK2 increase ph ...... stress-induced neuronal death
@en-gb
Mutations in LRRK2 increase ph ...... stress-induced neuronal death
@nl
type
label
Mutations in LRRK2 increase ph ...... stress-induced neuronal death
@ast
Mutations in LRRK2 increase ph ...... stress-induced neuronal death
@en
Mutations in LRRK2 increase ph ...... stress-induced neuronal death
@en-gb
Mutations in LRRK2 increase ph ...... stress-induced neuronal death
@nl
prefLabel
Mutations in LRRK2 increase ph ...... stress-induced neuronal death
@ast
Mutations in LRRK2 increase ph ...... stress-induced neuronal death
@en
Mutations in LRRK2 increase ph ...... stress-induced neuronal death
@en-gb
Mutations in LRRK2 increase ph ...... stress-induced neuronal death
@nl
P2093
P2860
P50
P921
P3181
P356
P1433
P1476
Mutations in LRRK2 increase ph ...... stress-induced neuronal death
@en
P2093
Bong-Hwa Gan
Dario C Angeles
Heather Melrose
Justus Dachsel
Kah-Leong Lim
Luisa Onstead
Matt Farrer
P2860
P304
P3181
P356
10.1002/HUMU.21582
P407
P577
2011-12-01T00:00:00Z