Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins
about
Biochemical characterization of Cdk2-Speedy/Ringo A2.Essential role of the Cdk2 activator RingoA in meiotic telomere tethering to the nuclear envelope.Spy1 expression prevents normal cellular responses to DNA damage: inhibition of apoptosis and checkpoint activationFine tuning the cell cycle: activation of the Cdk1 inhibitory phosphorylation pathway during mitotic exit.The cyclin-like protein Spy1/RINGO promotes mammary transformation and is elevated in human breast cancerEvolution of the Cdk-activator Speedy/RINGO in vertebrates.Ringo/cyclin-dependent kinase and mitogen-activated protein kinase signaling pathways regulate the activity of the cell fate determinant Musashi to promote cell cycle re-entry in Xenopus oocytesIdentification of novel markers of mouse fetal ovary development.Speedy/Ringo C regulates S and G2 phase progression in human cellsRole of LM23 in cell proliferation and apoptosis and its expression during the testis developmentLM23 is a novel member of the Speedy/Ringo family at the crossroads of life and death of spermatogenic cell.The atypical CDK activator Spy1 regulates the intrinsic DNA damage response and is dependent upon p53 to inhibit apoptosis.Speedy A-Cdk2 binding mediates initial telomere-nuclear envelope attachment during meiotic prophase I independent of Cdk2 activation.Cell adhesion to fibronectin down-regulates the expression of Spy1 and contributes to drug resistance in multiple myeloma cells.Revisiting CDK Inhibitors for Treatment of Glioblastoma Multiforme.Spy1 is frequently overexpressed in malignant gliomas and critically regulates the proliferation of glioma cells.The cyclin-dependent kinase activator, Spy1A, is targeted for degradation by the ubiquitin ligase NEDD4.Direct interactions with both p27 and Cdk2 regulate Spy1-mediated proliferation in vivo and in vitro.Structural basis of divergent cyclin-dependent kinase activation by Spy1/RINGO proteins.The atypical cell cycle regulator Spy1 suppresses differentiation of the neuroblastoma stem cell population.Acquisition of oocyte competence to develop as an embryo: integrated nuclear and cytoplasmic events.Cell cycle regulation of the mammalian CDK activator RINGO/Speedy A.Expression of Spy1 protein in human non-Hodgkin's lymphomas is correlated with phosphorylation of p27 Kip1 on Thr187 and cell proliferation.Peripheral nerve lesion induces an up-regulation of Spy1 in rat spinal cord.
P2860
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P2860
Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins
description
2005 nî lūn-bûn
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2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins
@ast
Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins
@en
Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins
@en-gb
Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins
@nl
type
label
Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins
@ast
Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins
@en
Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins
@en-gb
Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins
@nl
prefLabel
Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins
@ast
Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins
@en
Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins
@en-gb
Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins
@nl
P2093
P921
P3181
P356
P1433
P1476
Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins
@en
P2093
Aiyang Cheng
James E Ferrell
Mark J Solomon
P304
P3181
P356
10.4161/CC.4.1.1347
P407
P577
2005-01-01T00:00:00Z