Purification and cloning of a broad substrate specificity human liver carboxylesterase that catalyzes the hydrolysis of cocaine and heroin
about
Recommended nomenclature for five mammalian carboxylesterase gene families: human, mouse, and rat genes and proteinsObservation of an arsenic adduct in an acetyl esterase crystal structureIdentification, expression, and purification of a pyrethroid-hydrolyzing carboxylesterase from mouse liver microsomesHorse carboxylesterases: evidence for six CES1 and four families of CES genes on chromosome 3Mammalian carboxylesterase 3: comparative genomics and proteomicsBaboon carboxylesterases 1 and 2: sequences, structures and phylogenetic relationships with human and other primate carboxylesterasesBovine Carboxylesterases: Evidence for Two CES1 and Five Families of CES Genes on Chromosome 18Opossum carboxylesterases: sequences, phylogeny and evidence for CES gene duplication events predating the marsupial-eutherian common ancestorProperties of a newly identified esterase from Bacillus sp. K91 and its novel function in diisobutyl phthalate degradation.Cloning and expression of a cDNA encoding a hepatic microsomal lipase that mobilizes stored triacylglycerol.Molecular cloning and characterization of a novel carboxylesterase-like protein that is physiologically present at high concentrations in the urine of domestic cats (Felis catus).Characterization of pyrethroid hydrolysis by the human liver carboxylesterases hCE-1 and hCE-2.The effect of ethanol on oral cocaine pharmacokinetics reveals an unrecognized class of ethanol-mediated drug interactions.Macrophage cholesteryl ester mobilization and atherosclerosisEffect of Cellular Location of Human Carboxylesterase 2 on CPT-11 Hydrolysis and Anticancer ActivityGenomic structure and transcriptional regulation of the rat, mouse, and human carboxylesterase genes.Mammalian carboxylesterase 5: comparative biochemistry and genomics.Structure and catalytic properties of carboxylesterase isozymes involved in metabolic activation of prodrugs.A novel prodrug strategy to improve the oral absorption of O-desmethylvenlafaxine.Regulation of tissue-specific carboxylesterase expression by pregnane x receptor and constitutive androstane receptor.Mechanisms of acute cocaine toxicity.Evaluation of the transport, in vitro metabolism and pharmacokinetics of Salvinorin A, a potent hallucinogen.A new class of mammalian carboxylesterase CES6.Association of variants in MANEA with cocaine-related behaviors.Quantitative proteomic analysis of hepatocyte-secreted extracellular vesicles reveals candidate markers for liver toxicityNuclear receptor-mediated regulation of carboxylesterase expression and activity.Metabolism of drugs of abuse by cytochromes P450.Carboxylesterase inhibitors.Glycoengineering of Esterase Activity through Metabolic Flux-Based Modulation of Sialic Acid.Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants.Carboxylesterase 2 production and characterization in human cells: new insights into enzyme oligomerization and activity.Carboxylesterases in lipid metabolism: from mouse to human.Human carboxylesterase 2: Studies on the role of glycosylation for enzymatic activity.Improved, selective, human intestinal carboxylesterase inhibitors designed to modulate 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (Irinotecan; CPT-11) toxicity.Cocaine cardiovascular effects and pharmacokinetics after treatment with the acetylcholinesterase inhibitor donepezil.Comparison of benzil and trifluoromethyl ketone (TFK)-mediated carboxylesterase inhibition using classical and 3D-quantitative structure-activity relationship analysis.Biochemical and molecular analysis of carboxylesterase-mediated hydrolysis of cocaine and heroin.Evaluation of in vitro metabolic systems for common drugs of abuse. 1. Cocaine.Purification and characterization of rat hepatic microsomal low molecular weight fatty acid ethyl ester synthase and its relationship to carboxylesterases.The interference of ethanol with heroin-stimulated psychomotor activation in mice is not related to changed brain concentrations of the active metabolites 6MAM or morphine.
P2860
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P2860
Purification and cloning of a broad substrate specificity human liver carboxylesterase that catalyzes the hydrolysis of cocaine and heroin
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Purification and cloning of a ...... drolysis of cocaine and heroin
@ast
Purification and cloning of a ...... drolysis of cocaine and heroin
@en
Purification and cloning of a ...... drolysis of cocaine and heroin
@en-gb
Purification and cloning of a ...... drolysis of cocaine and heroin
@nl
type
label
Purification and cloning of a ...... drolysis of cocaine and heroin
@ast
Purification and cloning of a ...... drolysis of cocaine and heroin
@en
Purification and cloning of a ...... drolysis of cocaine and heroin
@en-gb
Purification and cloning of a ...... drolysis of cocaine and heroin
@nl
prefLabel
Purification and cloning of a ...... drolysis of cocaine and heroin
@ast
Purification and cloning of a ...... drolysis of cocaine and heroin
@en
Purification and cloning of a ...... drolysis of cocaine and heroin
@en-gb
Purification and cloning of a ...... drolysis of cocaine and heroin
@nl
P2093
P2860
P921
P356
P1476
Purification and cloning of a ...... drolysis of cocaine and heroin
@en
P2093
E V Pindel
M R Brzezinski
T L Abraham
W F Bosron
P2860
P304
14769-14775
P356
10.1074/JBC.272.23.14769
P407
P577
1997-06-01T00:00:00Z