Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes
about
Structural basis of selective ubiquitination of TRF1 by SCFFbx4Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cellsGNL3L stabilizes the TRF1 complex and promotes mitotic transitionA versatile viral system for expression and depletion of proteins in mammalian cellsTranscriptional activation of TINF2, a gene encoding the telomere-associated protein TIN2, by Sp1 and NF-κB factorsDistinct functions of POT1 at telomeres.A novel form of the telomere-associated protein TIN2 localizes to the nuclear matrixCrosstalk between telomere maintenance and radiation effects: A key player in the process of radiation-induced carcinogenesis.TIN2 protein dyskeratosis congenita missense mutants are defective in association with telomerase.Tpz1-Ccq1 and Tpz1-Poz1 interactions within fission yeast shelterin modulate Ccq1 Thr93 phosphorylation and telomerase recruitment.Mir-23a induces telomere dysfunction and cellular senescence by inhibiting TRF2 expression.Maintaining the end: roles of telomere proteins in end-protection, telomere replication and length regulationThe Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres.Dysfunctional telomeres induce p53-dependent and independent apoptosis to compromise cellular proliferation and inhibit tumor formation.Telomeric armor: the layers of end protection.Conditional TRF1 knockout in the hematopoietic compartment leads to bone marrow failure and recapitulates clinical features of dyskeratosis congenita.Conservation of telomere protein complexes: shuffling through evolution.Structural identity of telomeric complexes.Targeting the telomere and shelterin complex for cancer therapy: current views and future perspectives.Structural and functional association of androgen receptor with telomeres in prostate cancer cells.Telomeres and telomerase in prostate cancer development and therapy.Androgen receptor interacts with telomeric proteins in prostate cancer cells.Telomerase turns telomere dysfunction from bad to worseHuman RAP1 inhibits non-homologous end joining at telomeres.Trypanosoma brucei TIF2 suppresses VSG switching by maintaining subtelomere integrity.Tag team at the telomeres.The CCCTC-binding factor (CTCF)-forkhead box protein M1 axis regulates tumour growth and metastasis in hepatocellular carcinoma.Loss of RNA-binding protein HuR facilitates cellular senescence through posttranscriptional regulation of TIN2 mRNA.The C-terminal extension unique to the long isoform of the shelterin component TIN2 enhances its interaction with TRF2 in a phosphorylation- and dyskeratosis congenita-cluster-dependent fashion.Effects of TIN2 on telomeres and chromosomes in the human gastric epithelial cell line GES-1.
P2860
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P2860
Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes
@ast
Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes
@en
Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes
@en-gb
Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes
@nl
type
label
Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes
@ast
Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes
@en
Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes
@en-gb
Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes
@nl
prefLabel
Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes
@ast
Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes
@en
Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes
@en-gb
Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes
@nl
P2093
P2860
P921
P3181
P356
P1476
Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes
@en
P2093
Albert R Davalos
Christian Beausejour
Judith Campisi
Patrick Kaminker
Sahn-Ho Kim
Seok-Jin Heo
Steven M Yannone
P2860
P304
P3181
P356
10.1083/JCB.200710028
P407
P577
2008-04-28T00:00:00Z