Identification of the TCL1 gene involved in T-cell malignancies
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Dysregulated TCL1 promotes multiple classes of mature B cell lymphoma.Genomic analysis of human and mouse TCL1 loci reveals a complex of tightly clustered genesTcl1 enhances Akt kinase activity and mediates its nuclear translocationAbnormalities at 14q32.1 in T cell malignancies involve two oncogenesTORC2 regulates germinal center repression of the TCL1 oncoprotein to promote B cell development and inhibit transformationT cell leukemia I oncogene expression depends on the presence of Epstein-Barr virus in the virus-carrying Burkitt lymphoma linesCrystal structure of MTCP-1: implications for role of TCL-1 and MTCP-1 in T cell malignanciesIdentification, characterization and metagenome analysis of oocyte-specific genes organized in clusters in the mouse genomeTCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemiaCombating the epigenome: epigenetic drugs against non-Hodgkin's lymphomaSp1 transactivation of the TCL1 oncogeneExpression of the TCL1 gene at 14q32 in B-cell malignancies but not in adult T-cell leukemiaTCL1 participates in early embryonic development and is overexpressed in human seminomasProtooncogene TCL1b functions as an Akt kinase co-activator that exhibits oncogenic potency in vivo.Identification of Akt association and oligomerization domains of the Akt kinase coactivator TCL1Molecular portraits of B cell lineage commitment.Tcl1 interacts with Atm and enhances NF-κB activation in hematologic malignancies.Accurate molecular classification of cancer using simple rulesPeptide-mediated activation of Akt and extracellular regulated kinase signaling prevents lymphocyte apoptosis.Identification of the TCL6 genes within the breakpoint cluster region on chromosome 14q32 in T-cell leukemia.Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expressionIntegrated genomic sequencing reveals mutational landscape of T-cell prolymphocytic leukemiaIdentification of nerve growth factor-responsive element of the TCL1 promoter as a novel negative regulatory element.B cell receptors in TCL1 transgenic mice resemble those of aggressive, treatment-resistant human chronic lymphocytic leukemiaGenetic profile of insertion mutations in mouse leukemias and lymphomas.T-cell prolymphocytic leukemia: update and focus on alemtuzumab (Campath-1H).High-level DNA amplifications are common genetic aberrations in B-cell neoplasms.Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL)Dysregulated TCL1 requires the germinal center and genome instability for mature B-cell transformation.Deregulated expression of TCL1 causes T cell leukemia in miceHigh TCL1 expression and intact T-cell receptor signaling define a hyperproliferative subset of T-cell prolymphocytic leukemiaTCL1 oncogene expression in AIDS-related lymphomas and lymphoid tissues.Heat shock protein 70 regulates Tcl1 expression in leukemia and lymphomas.Direct isolation of human transcribed sequences from yeast artificial chromosomes through the application of RNA fingerprintingWhole-transcriptome analysis of flow-sorted cervical cancer samples reveals that B cell expressed TCL1A is correlated with improved survival.Plasmacytoid dendritic cell leukaemia/lymphoma: towards a well defined entity?BTK inhibition results in impaired CXCR4 chemokine receptor surface expression, signaling and function in chronic lymphocytic leukemia.MicroRNAs in the pathogeny of chronic lymphocytic leukaemia.Tcl1 functions as a transcriptional regulator and is directly involved in the pathogenesis of CLL.Prolymphocytic leukaemia of B- and T-cell subtype: a state-of-the-art paper.
P2860
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P2860
Identification of the TCL1 gene involved in T-cell malignancies
description
1994 nî lūn-bûn
@nan
1994 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Identification of the TCL1 gene involved in T-cell malignancies
@ast
Identification of the TCL1 gene involved in T-cell malignancies
@en
Identification of the TCL1 gene involved in T-cell malignancies
@en-gb
Identification of the TCL1 gene involved in T-cell malignancies
@nl
type
label
Identification of the TCL1 gene involved in T-cell malignancies
@ast
Identification of the TCL1 gene involved in T-cell malignancies
@en
Identification of the TCL1 gene involved in T-cell malignancies
@en-gb
Identification of the TCL1 gene involved in T-cell malignancies
@nl
prefLabel
Identification of the TCL1 gene involved in T-cell malignancies
@ast
Identification of the TCL1 gene involved in T-cell malignancies
@en
Identification of the TCL1 gene involved in T-cell malignancies
@en-gb
Identification of the TCL1 gene involved in T-cell malignancies
@nl
P2093
P2860
P356
P1476
Identification of the TCL1 gene involved in T-cell malignancies
@en
P2093
P2860
P304
P356
10.1073/PNAS.91.26.12530
P407
P577
1994-12-20T00:00:00Z