Posttranslationally processed structure of the human platelet protein smg p21B: evidence for geranylgeranylation and carboxyl methylation of the C-terminal cysteine
about
Prenyl group identification of rap2 proteins: a ras superfamily member other than ras that is farnesylatedAssociation of the low molecular weight GTP-binding protein rap2B with the cytoskeleton during platelet aggregationIsoprenoid modification of rab proteins terminating in CC or CXC motifsRAM2, an essential gene of yeast, and RAM1 encode the two polypeptide components of the farnesyltransferase that prenylates a-factor and Ras proteins.Protein geranylgeranyltransferase of Saccharomyces cerevisiae is specific for Cys-Xaa-Xaa-Leu motif proteins and requires the CDC43 gene product but not the DPR1 gene productMolecular cloning of the cDNA for stimulatory GDP/GTP exchange protein for smg p21s (ras p21-like small GTP-binding proteins) and characterization of stimulatory GDP/GTP exchange proteinActivated Drosophila Ras1 is selectively suppressed by isoprenyl transferase inhibitors.Structural analysis of protein prenyl groups and associated C-terminal modificationsRegulation of intracellular actin polymerization by prenylated cellular proteins.Genetic evidence for in vivo cross-specificity of the CaaX-box protein prenyltransferases farnesyltransferase and geranylgeranyltransferase-I in Saccharomyces cerevisiaeROCK and Rho: biochemistry and neuronal functions of Rho-associated protein kinasesNitric oxide stimulates the ADP-ribosylation of a 41-kDa cytosolic protein in Dictyostelium discoideum.A microsomal endoprotease that specifically cleaves isoprenylated peptidesMembrane-binding domain of the small G protein G25K contains an S-(all-trans-geranylgeranyl)cysteine methyl ester at its carboxyl terminus.A protein geranylgeranyltransferase from bovine brain: implications for protein prenylation specificity.C terminus of the small GTP-binding protein smg p25A contains two geranylgeranylated cysteine residues and a methyl esterA stimulatory GDP/GTP exchange protein for smg p21 is active on the post-translationally processed form of c-Ki-ras p21 and rhoA p21.Enzymatic modification of proteins with a geranylgeranyl isoprenoid.Posttranslational modification of Ha-ras p21 by farnesyl versus geranylgeranyl isoprenoids is determined by the COOH-terminal amino acidThe analytical determination of isoprenoid intermediates from the mevalonate pathway.Platelet activation and inhibition. Novel signal transduction mechanisms.Role of the C-terminal region of smg p25A in its interaction with membranes and the GDP/GTP exchange protein.Biology of the Rap proteins, members of the ras superfamily of GTP-binding proteinsIsoprenoid metabolism is required for stimulation of the respiratory burst oxidase of HL-60 cells.Carboxyl methylation and farnesylation of transducin gamma-subunit synergistically enhance its coupling with metarhodopsin II.Protein isoprenylation in suspension-cultured tobacco cells.A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins.Inhibition of cell growth of human hepatoma cell line (Hep G2) by a farnesyl protein transferase inhibitor: a preferential suppression of ras farnesylation.Activation of brain B-Raf protein kinase by Rap1B small GTP-binding protein.Identification of amino acid residues required for Ras p21 target activation.The effect of mevalonic acid deprivation on enzymes of DNA replication in cells emerging from quiescenceCyclic AMP-dependent activation of Rap1b.Endoproteolysis of non-CAAX-containing isoprenylated peptides.Rac1, a low-molecular-mass GTP-binding-protein with high intrinsic GTPase activity and distinct biochemical properties.Lysine beta311 of protein geranylgeranyltransferase type I partially replaces magnesium.A single activity carboxyl methylates both farnesyl and geranylgeranyl cysteine residues.Ultrastructural localization of the small GTP-binding protein Rap1 in human platelets and megakaryocytes.Polylysine and CVIM sequences of K-RasB dictate specificity of prenylation and confer resistance to benzodiazepine peptidomimetic in vitro.Inhibition of the action of a stimulatory GDP/GTP exchange protein for smg p21 by acidic membrane phospholipids.
P2860
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P2860
Posttranslationally processed structure of the human platelet protein smg p21B: evidence for geranylgeranylation and carboxyl methylation of the C-terminal cysteine
description
1990 nî lūn-bûn
@nan
1990 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Posttranslationally processed ...... ion of the C-terminal cysteine
@ast
Posttranslationally processed ...... ion of the C-terminal cysteine
@en
Posttranslationally processed ...... ion of the C-terminal cysteine
@en-gb
Posttranslationally processed ...... ion of the C-terminal cysteine
@nl
type
label
Posttranslationally processed ...... ion of the C-terminal cysteine
@ast
Posttranslationally processed ...... ion of the C-terminal cysteine
@en
Posttranslationally processed ...... ion of the C-terminal cysteine
@en-gb
Posttranslationally processed ...... ion of the C-terminal cysteine
@nl
prefLabel
Posttranslationally processed ...... ion of the C-terminal cysteine
@ast
Posttranslationally processed ...... ion of the C-terminal cysteine
@en
Posttranslationally processed ...... ion of the C-terminal cysteine
@en-gb
Posttranslationally processed ...... ion of the C-terminal cysteine
@nl
P2093
P2860
P356
P1476
Posttranslationally processed ...... ion of the C-terminal cysteine
@en
P2093
P2860
P304
P356
10.1073/PNAS.87.22.8960
P407
P577
1990-11-01T00:00:00Z