A peptide mimicking VGLL4 function acts as a YAP antagonist therapy against gastric cancer
about
Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleusRegulation of TAZ in cancerMechanisms of Hippo pathway regulationEmerging role of Hippo pathway in gastric and other gastrointestinal cancersThe TEAD Family and Its Oncogenic Role in Promoting TumorigenesisA Review: Molecular Aberrations within Hippo Signaling in Bone and Soft-Tissue SarcomasThe emerging molecular machinery and therapeutic targets of metastasisPharmacological targeting of kinases MST1 and MST2 augments tissue repair and regenerationTargeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer TherapyYAP and TAZ: a nexus for Hippo signaling and beyondEmerging evidence on the role of the Hippo/YAP pathway in liver physiology and cancerHippo Pathway in Organ Size Control, Tissue Homeostasis, and CancermiR-222/VGLL4/YAP-TEAD1 regulatory loop promotes proliferation and invasion of gastric cancer cells.Overexpression of Ras-GTPase-activating protein SH3 domain-binding protein 1 correlates with poor prognosis in gastric cancer patients.Structural and biochemical insights into the activation mechanisms of germinal center kinase OSR1.Molecular Pathways: Hippo Signaling, a Critical Tumor Suppressor.The role of the Hippo pathway in human disease and tumorigenesisCrystal structure of TAZ-TEAD complex reveals a distinct interaction mode from that of YAP-TEAD complex.Targeting YAP/TAZ-TEAD protein-protein interactions using fragment-based and computational modeling approaches.Identification of epigenetic interactions between miRNA and DNA methylation associated with gene expression as potential prognostic markers in bladder cancerHypoxia is a Key Driver of Alternative Splicing in Human Breast Cancer Cells.The Hippo pathway in disease and therapy: cancer and beyondDownstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinomaThe hippo pathway in heart development, regeneration, and diseasesExpression of Yes-associated protein in liver cancer and its correlation with clinicopathological features and prognosis of liver cancer patients.AMPK modulates Hippo pathway activity to regulate energy homeostasis.Hippo signaling pathway in liver and pancreas: the potential drug target for tumor therapy.Aerobic glycolysis tunes YAP/TAZ transcriptional activityA miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis.The emerging roles of YAP and TAZ in cancerYAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression.Targeting the Central Pocket in Human Transcription Factor TEAD as a Potential Cancer Therapeutic Strategy.Involvement of the Hippo pathway in regeneration and fibrogenesis after ischaemic acute kidney injury: YAP is the key effectorHistone demethylase JMJD2A drives prostate tumorigenesis through transcription factor ETV1.Autopalmitoylation of TEAD proteins regulates transcriptional output of the Hippo pathwayFat4 suppression induces Yap translocation accounting for the promoted proliferation and migration of gastric cancer cellsThe Hippo signal transduction network for exercise physiologistsETS transcription factor ERG cooperates with histone demethylase KDM4A.Yes-associated protein 1 and transcriptional coactivator with PDZ-binding motif activate the mammalian target of rapamycin complex 1 pathway by regulating amino acid transporters in hepatocellular carcinoma.Cullin 4A (CUL4A), a direct target of miR-9 and miR-137, promotes gastric cancer proliferation and invasion by regulating the Hippo signaling pathway.
P2860
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P2860
A peptide mimicking VGLL4 function acts as a YAP antagonist therapy against gastric cancer
description
2014 nî lūn-bûn
@nan
2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
A peptide mimicking VGLL4 func ...... therapy against gastric cancer
@ast
A peptide mimicking VGLL4 func ...... therapy against gastric cancer
@en
A peptide mimicking VGLL4 func ...... therapy against gastric cancer
@en-gb
A peptide mimicking VGLL4 func ...... therapy against gastric cancer
@nl
type
label
A peptide mimicking VGLL4 func ...... therapy against gastric cancer
@ast
A peptide mimicking VGLL4 func ...... therapy against gastric cancer
@en
A peptide mimicking VGLL4 func ...... therapy against gastric cancer
@en-gb
A peptide mimicking VGLL4 func ...... therapy against gastric cancer
@nl
prefLabel
A peptide mimicking VGLL4 func ...... therapy against gastric cancer
@ast
A peptide mimicking VGLL4 func ...... therapy against gastric cancer
@en
A peptide mimicking VGLL4 func ...... therapy against gastric cancer
@en-gb
A peptide mimicking VGLL4 func ...... therapy against gastric cancer
@nl
P2093
P3181
P1433
P1476
A peptide mimicking VGLL4 func ...... therapy against gastric cancer
@en
P2093
Aimei Dong
Hongbin Ji
Huizhen Wang
Wenjia Wang
Wenjing Zhang
Xiaomin Song
P304
P3181
P356
10.1016/J.CCR.2014.01.010
P407
P50
P577
2014-02-10T00:00:00Z