Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1
about
Active site remodelling accompanies thioester bond formation in the SUMO E1E2-RING expansion of the NEDD8 cascade confers specificity to cullin modificationLens epithelium-derived growth factor deSumoylation by Sumo-specific protease-1 regulates its transcriptional activation of small heat shock protein and the cellular responseImportin α/β mediates nuclear import of individual SUMO E1 subunits and of the holo-enzymeStructure of the Siz/PIAS SUMO E3 ligase Siz1 and determinants required for SUMO modification of PCNAUbiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathwaysStructure of the Escherichia coli ThiS-ThiF complex, a key component of the sulfur transfer system in thiamin biosynthesisAdvances in the development of SUMO specific protease (SENP) inhibitorsBasis for a ubiquitin-like protein thioester switch toggling E1–E2 affinityStructure of a SUMO-binding-motif Mimic Bound to Smt3p–Ubc9p: Conservation of a Non-covalent Ubiquitin-like Protein–E2 Complex as a Platform for Selective Interactions within a SUMO PathwayThe Intrinsic Affinity between E2 and the Cys Domain of E1 in Ubiquitin-like ModificationsMolecular mimicry of SUMO promotes DNA repairHow the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibioticCrystal Structure of the Human Ubiquitin-activating Enzyme 5 (UBA5) Bound to ATP: MECHANISTIC INSIGHTS INTO A MINIMALISTIC E1 ENZYMECrystal Structure of UBA2ufd-Ubc9: Insights into E1-E2 Interactions in Sumo PathwaysDNA Repair and Global Sumoylation Are Regulated by Distinct Ubc9 Noncovalent ComplexesNoncanonical E2 recruitment by the autophagy E1 revealed by Atg7–Atg3 and Atg7–Atg10 structuresAtg8 Transfer from Atg7 to Atg3: A Distinctive E1-E2 Architecture and Mechanism in the Autophagy PathwayInsights into noncanonical E1 enzyme activation from the structure of autophagic E1 Atg7 with Atg8Determinants of Small Ubiquitin-like Modifier 1 (SUMO1) Protein Specificity, E3 Ligase, and SUMO-RanGAP1 Binding Activities of Nucleoporin RanBP2Structure of a Ubiquitin E1-E2 Complex: Insights to E1-E2 Thioester TransferIdentification of Biochemically Distinct Properties of the Small Ubiquitin-related Modifier (SUMO) Conjugation Pathway in Plasmodium falciparumE2-binding surface on Uba3 β-grasp domain undergoes a conformational transitionStructure of the ubiquitin-activating enzyme loaded with two ubiquitin moleculesExpression, purification, and crystal structure of N-terminal domains of human ubiquitin-activating enzyme (E1)The basis for selective E1-E2 interactions in the ISG15 conjugation system.ISG15 Arg151 and the ISG15-conjugating enzyme UbE1L are important for innate immune control of Sindbis virusConformational transition associated with E1-E2 interaction in small ubiquitin-like modificationsRole of the Zn(2+) motif of E1 in SUMO adenylationThe SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition.Functional diversification of the RING finger and other binuclear treble clef domains in prokaryotes and the early evolution of the ubiquitin systemCrystal structure of a fragment of mouse ubiquitin-activating enzymePleiotropic effects of ATP.Mg2+ binding in the catalytic cycle of ubiquitin-activating enzymePerilous journey: a tour of the ubiquitin-proteasome systemA Chemical and Enzymatic Approach to Study Site-Specific SumoylationInsights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complexBuilding ubiquitin chains: E2 enzymes at workConstruction of a mouse Aos1-Uba2 chimeric SUMO-E1 enzyme, mAU, and its expression in baculovirus-insect cellsSystematic exploration of ubiquitin sequence, E1 activation efficiency, and experimental fitness in yeastSmall but versatile: the extraordinary functional and structural diversity of the beta-grasp fold
P2860
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P248
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P2860
Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1
description
2005 nî lūn-bûn
@nan
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Structures of the SUMO E1 prov ...... ation and E2 recruitment to E1
@ast
Structures of the SUMO E1 prov ...... ation and E2 recruitment to E1
@en
Structures of the SUMO E1 prov ...... ation and E2 recruitment to E1
@en-gb
Structures of the SUMO E1 prov ...... ation and E2 recruitment to E1
@nl
type
label
Structures of the SUMO E1 prov ...... ation and E2 recruitment to E1
@ast
Structures of the SUMO E1 prov ...... ation and E2 recruitment to E1
@en
Structures of the SUMO E1 prov ...... ation and E2 recruitment to E1
@en-gb
Structures of the SUMO E1 prov ...... ation and E2 recruitment to E1
@nl
prefLabel
Structures of the SUMO E1 prov ...... ation and E2 recruitment to E1
@ast
Structures of the SUMO E1 prov ...... ation and E2 recruitment to E1
@en
Structures of the SUMO E1 prov ...... ation and E2 recruitment to E1
@en-gb
Structures of the SUMO E1 prov ...... ation and E2 recruitment to E1
@nl
P2860
P921
P356
P1433
P1476
Structures of the SUMO E1 prov ...... ation and E2 recruitment to E1
@en
P2093
Christopher D Lima
Luisa Maria Lois
P2860
P304
P356
10.1038/SJ.EMBOJ.7600552
P407
P577
2005-02-09T00:00:00Z