CNOT2 depletion disrupts and inhibits the CCR4-NOT deadenylase complex and induces apoptotic cell death
about
miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOTC2ORF29/CNOT11 and CNOT10 form a new module of the CCR4-NOT complexCnot1, Cnot2, and Cnot3 maintain mouse and human ESC identity and inhibit extraembryonic differentiationThe role of the CNOT1 subunit of the CCR4-NOT complex in mRNA deadenylation and cell viabilityHeterogeneity and complexity within the nuclease module of the Ccr4-Not complexPost-transcriptional Control of Tumor Cell Autonomous Metastatic Potential by CCR4-NOT Deadenylase CNOT7Structure and RNA-binding properties of the Not1-Not2-Not5 module of the yeast Ccr4-Not complexStructure and assembly of the NOT module of the human CCR4-NOT complexObesity resistance and increased hepatic expression of catabolism-related mRNAs in Cnot3+/- miceInsights into the structure and architecture of the CCR4-NOT complexMultifunctional roles of the mammalian CCR4-NOT complex in physiological phenomena.CNOT3 contributes to early B cell development by controlling Igh rearrangement and p53 mRNA stability.CNOT3 suppression promotes necroptosis by stabilizing mRNAs for cell death-inducing proteinsHIPK family kinases bind and regulate the function of the CCR4-NOT complex.An integrated systems genetics screen reveals the transcriptional structure of inherited predisposition to metastatic diseaseThe transcription factor ERG recruits CCR4-NOT to control mRNA decay and mitotic progression.CNOT2 promotes degradation of p62/SQSTM1 as a negative regulator in ATG5 dependent autophagy.Trypanosome CNOT10 is essential for the integrity of the NOT deadenylase complex and for degradation of many mRNAsThe CCR4-NOT complex contributes to repression of Major Histocompatibility Complex class II transcription.Reparameterization of PAM50 expression identifies novel breast tumor dimensions and leads to discovery of a genomewide significant breast cancer locus at 12q15.The CCR4-NOT complex is a tumor suppressor in Drosophila melanogaster eye cancer models
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P2860
CNOT2 depletion disrupts and inhibits the CCR4-NOT deadenylase complex and induces apoptotic cell death
description
2011 nî lūn-bûn
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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
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2011年論文
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2011年論文
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2011年论文
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name
CNOT2 depletion disrupts and i ...... d induces apoptotic cell death
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CNOT2 depletion disrupts and i ...... d induces apoptotic cell death
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CNOT2 depletion disrupts and i ...... d induces apoptotic cell death
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CNOT2 depletion disrupts and i ...... d induces apoptotic cell death
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CNOT2 depletion disrupts and i ...... d induces apoptotic cell death
@ast
CNOT2 depletion disrupts and i ...... d induces apoptotic cell death
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CNOT2 depletion disrupts and i ...... d induces apoptotic cell death
@en-gb
CNOT2 depletion disrupts and i ...... d induces apoptotic cell death
@nl
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CNOT2 depletion disrupts and i ...... d induces apoptotic cell death
@ast
CNOT2 depletion disrupts and i ...... d induces apoptotic cell death
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CNOT2 depletion disrupts and i ...... d induces apoptotic cell death
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CNOT2 depletion disrupts and i ...... d induces apoptotic cell death
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CNOT2 depletion disrupts and i ...... d induces apoptotic cell death
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Kazumasa Yokoyama
Kentaro Ito
Masahiro Morita
Tadashi Yamamoto
Takeshi Inoue
Toru Suzuki
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P304
P3181
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10.1111/J.1365-2443.2011.01492.X
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P577
2011-04-01T00:00:00Z