about
A short guided tour through functional and structural features of saposin-like proteinsEvidence for two cDNA clones encoding human GM2-activator proteinDistribution of saposin proteins (sphingolipid activator proteins) in lysosomal storage and other diseasesCharacterization of a mutation in a family with saposin B deficiency: a glycosylation site defectAn association analysis of murine anxiety genes in humans implicates novel candidate genes for anxiety disordersAcid sphingomyelinase possesses a domain homologous to its activator proteins: saposins B and DThe role of saposin C in Gaucher diseaseThe protective role of prosaposin and its receptors in the nervous systemInsights into Krabbe disease from structures of galactocerebrosidaseThe organization of the gene for the human cerebroside sulfate activator proteinIdentification of a novel sequence involved in lysosomal sorting of the sphingolipid activator protein prosaposin.Primary and secondary structure of the pore-forming peptide of pathogenic Entamoeba histolytica.Role of prosaposin in the male reproductive system: effect of prosaposin inactivation on the testis, epididymis, prostate, and seminal vesicles.Biosynthesis and degradation of mammalian glycosphingolipids.Prevalence of nine mutations among Jewish and non-Jewish Gaucher disease patientsCorrection of sulfatide metabolism after transfer of prosaposin cDNA to cultured cells from a patient with SAP-1 deficiencyProsaposin overexpression following kainic acid-induced neurotoxicity.Analysis of a splice-site mutation in the sap-precursor gene of a patient with metachromatic leukodystrophy.Epidermal sphingolipids: metabolism, function, and roles in skin disorders.Prosaposin inhibits tumor metastasis via paracrine and endocrine stimulation of stromal p53 and Tsp-1Function and regulation of expression of pulmonary surfactant-associated proteins.A saposin deficiency model in Drosophila: Lysosomal storage, progressive neurodegeneration and sensory physiological declineInsertion in the mRNA of a metachromatic leukodystrophy patient with sphingolipid activator protein-1 deficiency.The immunological functions of saposins.Acid beta-glucosidase: enzymology and molecular biology of Gaucher disease.Differential membrane interactions of saposins A and C: implications for the functional specificity.Role of sialic acid in the endocytosis of prosaposin by the nonciliated cells of the rat efferent ducts.Lipids regulate the hydrolysis of membrane bound glucosylceramide by lysosomal β-glucocerebrosidase.Structure of human saposin A at lysosomal pH.Saposins (sap) A and C activate the degradation of galactosylsphingosine.Saposins (sap) A and C activate the degradation of galactosylceramide in living cells.Proteolytic processing patterns of prosaposin in insect and mammalian cells.Lysosomal storage diseases: heterogeneous group of disordersA stretch of 17 amino acids in the prosaposin C terminus is critical for its binding to sortilin and targeting to lysosomes.Additional biochemical findings in a patient and fetal sibling with a genetic defect in the sphingolipid activator protein (SAP) precursor, prosaposin. Evidence for a deficiency in SAP-1 and for a normal lysosomal neuraminidase.Saposin C is required for normal resistance of acid beta-glucosidase to proteolytic degradation.Distribution of saposins (sphingolipid activator proteins) in tissues of lysosomal storage disease patients.Structural analysis of the mouse prosaposin (SGP-1) gene reveals the presence of an exon that is alternatively spliced in transcribed mRNAs.The mechanism of glycosphingolipid degradation revealed by a GALC-SapA complex structure.Isolation of proliferation factor of immature T-cell clone in concanavalin A-stimulated splenocyte culture supernatant.
P2860
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P2860
description
1989 nî lūn-bûn
@nan
1989 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Saposin A: second cerebrosidase activator protein
@ast
Saposin A: second cerebrosidase activator protein
@en
Saposin A: second cerebrosidase activator protein
@en-gb
Saposin A: second cerebrosidase activator protein
@nl
type
label
Saposin A: second cerebrosidase activator protein
@ast
Saposin A: second cerebrosidase activator protein
@en
Saposin A: second cerebrosidase activator protein
@en-gb
Saposin A: second cerebrosidase activator protein
@nl
prefLabel
Saposin A: second cerebrosidase activator protein
@ast
Saposin A: second cerebrosidase activator protein
@en
Saposin A: second cerebrosidase activator protein
@en-gb
Saposin A: second cerebrosidase activator protein
@nl
P2093
P2860
P356
P1476
Saposin A: second cerebrosidase activator protein
@en
P2093
B M Martin
J S O'Brien
S Morimoto
Y Kishimoto
Y Yamamoto
P2860
P304
P356
10.1073/PNAS.86.9.3389
P407
P577
1989-05-01T00:00:00Z