Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma
about
Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven CancersRUNX family members are covalently modified and regulated by PIAS1-mediated sumoylationMolecular pathways and therapeutic targets in lung cancerClinicopathological significance and potential drug target of RUNX3 in breast cancer.HDAC inhibitors target HDAC5, upregulate microRNA-125a-5p, and induce apoptosis in breast cancer cellsBaicalein increases the expression and reciprocal interplay of RUNX3 and FOXO3a through crosstalk of AMPKα and MEK/ERK1/2 signaling pathways in human non-small cell lung cancer cells.RUNX3 Controls a Metastatic Switch in Pancreatic Ductal AdenocarcinomaRAC-LATS1/2 signaling regulates YAP activity by switching between the YAP-binding partners TEAD4 and RUNX3.RUNX3 is oncogenic in natural killer/T-cell lymphoma and is transcriptionally regulated by MYC.The RUNX Genes as Conditional Oncogenes: Insights from Retroviral Targeting and Mouse Models.RAS signaling and anti-RAS therapy: lessons learned from genetically engineered mouse models, human cancer cells, and patient-related studies.Targeting of RUNX3 by miR-130a and miR-495 cooperatively increases cell proliferation and tumor angiogenesis in gastric cancer cells.How do K-RAS-activated cells evade cellular defense mechanisms?TrkB Promotes Breast Cancer Metastasis via Suppression of Runx3 and Keap1 ExpressionLoss of RUNX3 expression promotes cancer-associated bone destruction by regulating CCL5, CCL19 and CXCL11 in non-small cell lung cancerAurora kinase-induced phosphorylation excludes transcription factor RUNX from the chromatin to facilitate proper mitotic progression.The clinicopathological significance of RUNX3 hypermethylation and mRNA expression in human breast cancer, a meta-analysis.Clinicopathological significance of RUNX3 gene hypermethylation in hepatocellular carcinoma.The RUNX family: developmental regulators in cancer.Lineage factors and differentiation states in lung cancer progression.Clinicopathological significance and potential drug target of RUNX3 in non-small cell lung cancer: a meta-analysis.Targeting epigenetic regulators for cancer therapy: modulation of bromodomain proteins, methyltransferases, demethylases, and microRNAs.Runx3 in Immunity, Inflammation and Cancer.Covalent Modifications of RUNX Proteins: Structure Affects Function.Roles of RUNX in Hypoxia-Induced Responses and Angiogenesis.UnPAKing RUNX3 functions-Both sides of the coin.RUNX3 is a novel negative regulator of oncogenic TEAD-YAP complex in gastric cancer.Runx3 is a key modulator during the epithelial-mesenchymal transition of alveolar type II cells in animal models of BPD.Gene signature driving invasive mucinous adenocarcinoma of the lung.Aurora kinase and RUNX: Reaching beyond transcription.RUNX3 regulates p14-ARFRunx3 plays a critical role in restriction-point and defense against cellular transformation.Loss of RUNX1 is associated with aggressive lung adenocarcinomas.Roles of RUNX in Hippo Pathway Signaling.p53 loss does not permit escape from BrafV600E-induced senescence in a mouse model of lung cancer.Emerging role of RUNX3 in the regulation of tumor microenvironment.RUNX3 binds EP300EP300 acetylates RUNX3Acetylated RUNX3 binds to BRD2RUNX proteins bind the p14-ARF promoter at the CDKN2A locus
P2860
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P2860
Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma
description
2013 nî lūn-bûn
@nan
2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma
@ast
Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma
@en
Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma
@en-gb
Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma
@nl
type
label
Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma
@ast
Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma
@en
Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma
@en-gb
Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma
@nl
prefLabel
Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma
@ast
Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma
@en
Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma
@en-gb
Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma
@nl
P2093
P3181
P1433
P1476
Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma
@en
P2093
Byeung-Sub Choi
Eung-Gook Kim
Jang-Hyun Kim
Jin-Haeng Chung
Joo-Won Suh
Ju-Won Jang
Jung-Won Lee
Linda Shyue Huey Chuang
Min-Kyu Kim
P304
P3181
P356
10.1016/J.CCR.2013.10.003
P407
P577
2013-11-11T00:00:00Z