Human cytomegalovirus tegument protein pUL83 inhibits IFI16-mediated DNA sensing for immune evasion
about
Immune Activation in the Liver by Nucleic AcidsCytosolic Innate Immune Sensing and Signaling upon InfectionThe enemy within: endogenous retroelements and autoimmune diseaseThe innate immune sensor IFI16 recognizes foreign DNA in the nucleus by scanning along the duplex.Proteomic approaches to uncovering virus-host protein interactions during the progression of viral infectionThe Role of Nuclear Antiviral Factors against Invading DNA Viruses: The Immediate Fate of Incoming Viral GenomesInnate immune recognition of DNA: A recent historyInflammasome control of viral infectionViral evasion of intracellular DNA and RNA sensingMurine Cytomegalovirus Deubiquitinase Regulates Viral Chemokine Levels To Control Inflammation and PathogenesisIFI16 restricts HSV-1 replication by accumulating on the hsv-1 genome, repressing HSV-1 gene expression, and directly or indirectly modulating histone modificationsThe murine cytomegalovirus M35 protein antagonizes type I IFN induction downstream of pattern recognition receptors by targeting NF-κB mediated transcriptionAssembly-driven activation of the AIM2 foreign-dsDNA sensor provides a polymerization template for downstream ASCInnate nuclear sensor IFI16 translocates into the cytoplasm during the early stage of in vitro human cytomegalovirus infection and is entrapped in the egressing virions during the late stage.cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection.IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMPMicroRNA editing facilitates immune elimination of HCMV infected cells.Nuclear sensing of viral DNA, epigenetic regulation of herpes simplex virus infection, and innate immunityWhat's the damage? The impact of pathogens on pathways that maintain host genome integritycGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived Cells.Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 ImmunosuppressionHuman Cytomegalovirus Immediate-Early 1 Protein Rewires Upstream STAT3 to Downstream STAT1 Signaling Switching an IL6-Type to an IFNγ-Like ResponseThe life cycle and pathogenesis of human cytomegalovirus infection: lessons from proteomicsThe emerging role of nuclear viral DNA sensors.Leukocyte Immunoglobulin-Like Receptor 1-Expressing Human Natural Killer Cell Subsets Differentially Recognize Isolates of Human Cytomegalovirus through the Viral Major Histocompatibility Complex Class I Homolog UL18.cGAS-STING Signaling Regulates Initial Innate Control of Cytomegalovirus InfectionHuman Papillomavirus Entry: Hiding in a BubbleViral DNA Sensors IFI16 and Cyclic GMP-AMP Synthase Possess Distinct Functions in Regulating Viral Gene Expression, Immune Defenses, and Apoptotic Responses during Herpesvirus Infection.Role of nucleotide-binding oligomerization domain 1 (NOD1) and its variants in human cytomegalovirus control in vitro and in vivo.Cooperative assembly of IFI16 filaments on dsDNA provides insights into host defense strategy.Interaction between HCMV pUL83 and human AIM2 disrupts the activation of the AIM2 inflammasome.B cell epitope of human cytomegalovirus phosphoprotein 65 (HCMV pp65) induced anti-dsDNA antibody in BALB/c mice.A mass spectrometry view of stable and transient protein interactions.Cellular sensing of viral DNA and viral evasion mechanisms.Microbial DNA recognition by cGAS-STING and other sensors in dendritic cells in inflammatory bowel diseases.A proteomics perspective on viral DNA sensors in host defense and viral immune evasion mechanisms.Cytomegalovirus immune evasion of myeloid lineage cells.The roles of interferon-inducible p200 family members IFI16 and p204 in innate immune responses, cell differentiation and proliferation.Activation and regulation of DNA-driven immune responses.The cGAS-STING Defense Pathway and Its Counteraction by Viruses.
P2860
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P2860
Human cytomegalovirus tegument protein pUL83 inhibits IFI16-mediated DNA sensing for immune evasion
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2013 nî lūn-bûn
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2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年論文
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2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Human cytomegalovirus tegument ...... DNA sensing for immune evasion
@ast
Human cytomegalovirus tegument ...... DNA sensing for immune evasion
@en
Human cytomegalovirus tegument ...... DNA sensing for immune evasion
@en-gb
Human cytomegalovirus tegument ...... DNA sensing for immune evasion
@nl
type
label
Human cytomegalovirus tegument ...... DNA sensing for immune evasion
@ast
Human cytomegalovirus tegument ...... DNA sensing for immune evasion
@en
Human cytomegalovirus tegument ...... DNA sensing for immune evasion
@en-gb
Human cytomegalovirus tegument ...... DNA sensing for immune evasion
@nl
prefLabel
Human cytomegalovirus tegument ...... DNA sensing for immune evasion
@ast
Human cytomegalovirus tegument ...... DNA sensing for immune evasion
@en
Human cytomegalovirus tegument ...... DNA sensing for immune evasion
@en-gb
Human cytomegalovirus tegument ...... DNA sensing for immune evasion
@nl
P2093
P2860
P3181
P1433
P1476
Human cytomegalovirus tegument ...... DNA sensing for immune evasion
@en
P2093
Ileana M Cristea
P2860
P3181
P356
10.1016/J.CHOM.2013.10.007
P407
P577
2013-11-13T00:00:00Z