I-SceI-induced gene replacement at a natural locus in embryonic stem cells
about
In vivo selection of engineered homing endonucleases using double-strand break induced homologous recombinationA highly sensitive selection method for directed evolution of homing endonucleases.Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairsRational protein design: developing next-generation biological therapeutics and nanobiotechnological toolsGene targeting using zinc finger nucleasesOligo/polynucleotide-based gene modification: strategies and therapeutic potentialIn vivo, villin is required for Ca(2+)-dependent F-actin disruption in intestinal brush bordersI-SceI-mediated double-strand break does not increase the frequency of homologous recombination at the Dct locus in mouse embryonic stem cellsUse of Transgenic Animals to Improve Human Health and Animal ProductionA comparison of synthetic oligodeoxynucleotides, DNA fragments and AAV-1 for targeted episomal and chromosomal gene repairStimulation of homologous recombination through targeted cleavage by chimeric nucleases.A novel engineered meganuclease induces homologous recombination in yeast and mammalian cellsManipulating the mammalian genome by homologous recombinationGenome engineering via homologous recombination in mouse embryonic stem (ES) cells: an amazingly versatile tool for the study of mammalian biology.Multiple origins of Cajal-Retzius cells at the borders of the developing pallium.Efficient gene targeting in Drosophila with zinc-finger nucleasesEngineered zinc finger nuclease-mediated homologous recombination of the human rhodopsin geneReconstruction of mreB expression in Staphylococcus aureus via a collection of new integrative plasmidsEngineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases.Targeted genetic modification of cell lines for recombinant protein production.Deletion of many yeast introns reveals a minority of genes that require splicing for function.Directed evolution of homing endonuclease I-SceI with altered sequence specificity.Zinc Finger Nucleases: Tailor-made for Gene TherapyHigh-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display.Optimization of the production of knock-in alleles by CRISPR/Cas9 microinjection into the mouse zygote.Molecular scissors for in situ cellular repair.Genome editing: a robust technology for human stem cells.A history of genome editing in mammals.Construction of a recombinant adenovirus for efficient delivery of the I-SceI yeast endonuclease to human cells and its application in the in vivo cleavage of chromosomes to expose new potential telomeresImproving gene replacement by intracellular formation of linear homologous DNA.IFN-gamma induces apoptosis in mouse embryonic stem cells, a putative mechanism of its embryotoxicity.Meganuclease-mediated virus self-cleavage facilitates tumor-specific virus replication.Efficient in toto targeted recombination in mouse liver by meganuclease-induced double-strand break.Meganuclease-assisted generation of stable transgenics in the sea anemone Nematostella vectensis.Use of gene-editing technology to introduce targeted modifications in pigs.
P2860
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P2860
I-SceI-induced gene replacement at a natural locus in embryonic stem cells
description
1998 nî lūn-bûn
@nan
1998 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մարտին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
I-SceI-induced gene replacement at a natural locus in embryonic stem cells
@ast
I-SceI-induced gene replacement at a natural locus in embryonic stem cells
@en
I-SceI-induced gene replacement at a natural locus in embryonic stem cells
@en-gb
I-SceI-induced gene replacement at a natural locus in embryonic stem cells
@nl
type
label
I-SceI-induced gene replacement at a natural locus in embryonic stem cells
@ast
I-SceI-induced gene replacement at a natural locus in embryonic stem cells
@en
I-SceI-induced gene replacement at a natural locus in embryonic stem cells
@en-gb
I-SceI-induced gene replacement at a natural locus in embryonic stem cells
@nl
prefLabel
I-SceI-induced gene replacement at a natural locus in embryonic stem cells
@ast
I-SceI-induced gene replacement at a natural locus in embryonic stem cells
@en
I-SceI-induced gene replacement at a natural locus in embryonic stem cells
@en-gb
I-SceI-induced gene replacement at a natural locus in embryonic stem cells
@nl
P2093
P2860
P356
P1476
I-SceI-induced gene replacement at a natural locus in embryonic stem cells
@en
P2093
F El Marjou
M Cohen-Tannoudji
P2860
P304
P356
10.1128/MCB.18.3.1444
P407
P577
1998-03-01T00:00:00Z