Enhanced levels of Hsulf-1 interfere with heparin-binding growth factor signaling in pancreatic cancer.
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Direct detection of HSulf-1 and HSulf-2 activities on extracellular heparan sulfate and their inhibition by PI-88HSulf-1 modulates FGF2- and hypoxia-mediated migration and invasion of breast cancer cellsHSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1.Sulfatase 2 up-regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinomaHeparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativityHsulf-1 regulates growth and invasion of pancreatic cancer cellsSubendothelial heparan sulfate proteoglycans become major L-selectin and monocyte chemoattractant protein-1 ligands upon renal ischemia/reperfusionSULF2 methylation is associated with in vitro cisplatin sensitivity and clinical efficacy for gastric cancer patients treated with a modified FOLFOX regimenA combined approach to data mining of textual and structured data to identify cancer-related targets.Extracellular sulfatases, elements of the Wnt signaling pathway, positively regulate growth and tumorigenicity of human pancreatic cancer cellsPredicting sulfotyrosine sites using the random forest algorithm with significantly improved prediction accuracy.hSulf-1 gene exhibits anticancer efficacy through negatively regulating VEGFR-2 signaling in human cancersSulfatase 1 (hSulf-1) reverses basic fibroblast growth factor-stimulated signaling and inhibits growth of hepatocellular carcinoma in animal modelDrosophila heparan sulfate 6-O endosulfatase regulates Wingless morphogen gradient formation.Polymorphisms in the SULF1 gene are associated with early age of onset and survival of ovarian cancer.Expression regulation and function of heparan sulfate 6-O-endosulfatases in the spermatogonial stem cell nicheA genome-wide methylation study on essential hypertension in young African American malesWhole genome SNP genotyping and exome sequencing reveal novel genetic variants and putative causative genes in congenital hyperinsulinism.Sulfatase 1 and sulfatase 2 in hepatocellular carcinoma: associated signaling pathways, tumor phenotypes, and survival.Aberrant signaling pathways in pancreatic cancer: a two compartment view.Restoration of epigenetically silenced SULF1 expression by 5-aza-2-deoxycytidine sensitizes hepatocellular carcinoma cells to chemotherapy-induced apoptosisSULF2 Expression Is a Potential Diagnostic and Prognostic Marker in Lung Cancer.Single-nucleotide polymorphism in microRNA-binding site of SULF1 target gene as a protective factor against the susceptibility to breast cancer: a case-control study.HSulf-1 suppresses cell growth and down-regulates Hedgehog signaling in human gastric cancer cellsSULF2 expression by immunohistochemistry and overall survival in oesophageal cancer: a cohort study.Endosulfatases SULF1 and SULF2 limit Chlamydia muridarum infection.Heparin-degrading sulfatases in hepatocellular carcinoma: roles in pathogenesis and therapy targets.The tumor suppressor function of human sulfatase 1 (SULF1) in carcinogenesis.hSulf-1 inhibits cell proliferation and migration and promotes apoptosis by suppressing stat3 signaling in hepatocellular carcinoma.Sulf-2: an extracellular modulator of cell signaling and a cancer target candidate.The way Wnt works: components and mechanism.Post-Synthetic Regulation of HS Structure: The Yin and Yang of the Sulfs in Cancer.The Role of Heparanase and Sulfatases in the Modification of Heparan Sulfate Proteoglycans within the Tumor Microenvironment and Opportunities for Novel Cancer Therapeutics.The "in and out" of glucosamine 6-O-sulfation: the 6th sense of heparan sulfate.Sulfatase-1 overexpression indicates poor prognosis in urothelial carcinoma of the urinary bladder and upper tractSULF2 overexpression positively regulates tumorigenicity of human prostate cancer cellsSULF1 inhibits proliferation and invasion of esophageal squamous cell carcinoma cells by decreasing heparin-binding growth factor signaling.HSULF-1 inhibits ERK and AKT signaling and decreases cell viability in vitro in human lung epithelial cells.Up-regulated expression of sulfatases (SULF1 and SULF2) as prognostic and metastasis predictive markers in human gastric cancer.Computational and biological evaluation of quinazolinone prodrug for targeting pancreatic cancer.
P2860
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P2860
Enhanced levels of Hsulf-1 interfere with heparin-binding growth factor signaling in pancreatic cancer.
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Enhanced levels of Hsulf-1 int ...... signaling in pancreatic cancer
@nl
Enhanced levels of Hsulf-1 int ...... ignaling in pancreatic cancer.
@ast
Enhanced levels of Hsulf-1 int ...... ignaling in pancreatic cancer.
@en
Enhanced levels of Hsulf-1 int ...... ignaling in pancreatic cancer.
@en-gb
type
label
Enhanced levels of Hsulf-1 int ...... signaling in pancreatic cancer
@nl
Enhanced levels of Hsulf-1 int ...... ignaling in pancreatic cancer.
@ast
Enhanced levels of Hsulf-1 int ...... ignaling in pancreatic cancer.
@en
Enhanced levels of Hsulf-1 int ...... ignaling in pancreatic cancer.
@en-gb
prefLabel
Enhanced levels of Hsulf-1 int ...... signaling in pancreatic cancer
@nl
Enhanced levels of Hsulf-1 int ...... ignaling in pancreatic cancer.
@ast
Enhanced levels of Hsulf-1 int ...... ignaling in pancreatic cancer.
@en
Enhanced levels of Hsulf-1 int ...... ignaling in pancreatic cancer.
@en-gb
P2093
P2860
P50
P3181
P356
P1433
P1476
Enhanced levels of Hsulf-1 int ...... ignaling in pancreatic cancer.
@en
P2093
Hany Kayed
Ivane Abiatari
Junsheng Li
Jörg Kleeff
Klaus Felix
Nathalia A Giese
Thomas Giese
P2860
P2888
P3181
P356
10.1186/1476-4598-4-14
P407
P577
2005-04-07T00:00:00Z
P5875
P6179
1029495917