Inhibitory effect of okadaic acid derivatives on protein phosphatases. A study on structure-affinity relationship
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Single laboratory validation of a ready-to-use phosphatase inhibition assay for detection of okadaic acid toxinsExperimental basis for the high oral toxicity of dinophysistoxin 1: a comparative study of DSPIs protein phosphatase inhibition responsible for the toxic effects of okadaic Acid in animals?Crystal structure of the tumor-promoter okadaic acid bound to protein phosphatase-1The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradationXIAP BIR domain suppresses miR-200a expression and subsequently promotes EGFR protein translation and anchorage-independent growth of bladder cancer cellRole of protein phosphatases in the regulation of human mast cell and basophil function.Ppg1, a PP2A-type protein phosphatase, controls filament extension and virulence in Candida albicans.Toxic marine dinoflagellates in Singapore waters that cause seafood poisonings.Regulation of human basophil function by phosphatase inhibitors.A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regionsIn vitro acylation of okadaic acid in the presence of various bivalves' extracts.Azaspiracid substituent at C1 is relevant to in vitro toxicity.Marine toxins and the cytoskeleton: okadaic acid and dinophysistoxins.Structure-Activity Relationship Studies Using Natural and Synthetic Okadaic Acid/Dinophysistoxin Toxins.Greatwall-phosphorylated Endosulfine is both an inhibitor and a substrate of PP2A-B55 heterotrimers.Okadaic acid: more than a diarrheic toxin.Comparative analysis of the cytotoxic effects of okadaic acid-group toxins on human intestinal cell lines.Protein phosphatases 1 and 2A and their naturally occurring inhibitors: current topics in smooth muscle physiology and chemical biology.New Invertebrate Vectors of Okadaic Acid from the North Atlantic Waters--Portugal (Azores and Madeira) and Morocco.The methyl ester of okadaic acid is more potent than okadaic acid in disrupting the actin cytoskeleton and metabolism of primary cultured hepatocytesInduction of actin cytoskeleton rearrangement by methyl okadaate--comparison with okadaic acid.β-Adrenergic Stimulation Induces Histone Deacetylase 5 (HDAC5) Nuclear Accumulation in Cardiomyocytes by B55α-PP2A-Mediated Dephosphorylation.Protein phosphatase 2A reverses inhibition of inward rectifying K+ currents by thyrotropin-releasing hormone in GH3 pituitary cells.Inhibition of specific binding of okadaic acid to protein phosphatase 2A by microcystin-LR, calyculin-A and tautomycin: method of analysis of interactions of tight-binding ligands with target protein.Effects of modification of the hydrophobic C-1-C-16 segment of tautomycin on its affinity to type-1 and type-2A protein phosphatases.Affinity of okadaic acid to type-1 and type-2A protein phosphatases is markedly reduced by oxidation of its 27-hydroxyl group.Estimation of the rate constants associated with the inhibitory effect of okadaic acid on type 2A protein phosphatase by time-course analysis.Characterization of fatty acid esters of okadaic acid and related toxins in blue mussels (Mytilus edulis) from Norway.Marine biotoxins in shellfish - okadaic acid and analogues - Scientific Opinion of the Panel on Contaminants in the Food chainMixtures of Lipophilic Phycotoxins: Exposure Data and Toxicological Assessment.Accumulation and Tissue Distribution of Dinophysitoxin-1 and Dinophysitoxin-3 in the Mussel Crenomytilus grayanus Feeding on the Benthic Dinoflagellate Prorocentrum foraminosum.Label-free okadaic acid detection using growth of gold nanoparticles in sensor gaps as a conductive tag.Development of a novel immunobiosensor method for the rapid detection of okadaic acid contamination in shellfish extracts.Prorocentrolide-A from Cultured Prorocentrum lima Dinoflagellates Collected in Japan Blocks Sub-Types of Nicotinic Acetylcholine Receptors.
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P2860
Inhibitory effect of okadaic acid derivatives on protein phosphatases. A study on structure-affinity relationship
description
1992 nî lūn-bûn
@nan
1992 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
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Inhibitory effect of okadaic a ...... tructure-affinity relationship
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10.1042/BJ2840539
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284 ( Pt 2)
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1992-06-01T00:00:00Z