In vivo HP1 targeting causes large-scale chromatin condensation and enhanced histone lysine methylation
about
The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cellsThe assembly and maintenance of heterochromatin initiated by transgene repeats are independent of the RNA interference pathway in mammalian cellsCooperative epigenetic modulation by cancer amplicon genesCross-talk between site-specific transcription factors and DNA methylation statesTranscriptional repression of Hox genes by C. elegans HP1/HPL and H1/HIS-24Modulation of the Chromatin Phosphoproteome by the Haspin Protein KinaseChromatin unfolding by Cdt1 regulates MCM loading via opposing functions of HBO1 and HDAC11-geminin.Stable S/MAR-based episomal vectors are regulated at the chromatin levelGrainyhead-like 2 inhibits the coactivator p300, suppressing tubulogenesis and the epithelial-mesenchymal transition.A role for MeCP2 in switching gene activity via chromatin unfolding and HP1γ displacement.Drosophila SETDB1 is required for chromosome 4 silencingChromatin structure regulates gene conversion.The impact of local genome sequence on defining heterochromatin domains.Chromatin condensation modulates access and binding of nuclear proteins.Combinatorial, site-specific requirement for heterochromatic silencing factors in the elimination of nucleosome-free regions.The spatiotemporal dynamics of chromatin protein HP1α is essential for accurate chromosome segregation during cell division.A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure.Setdb1-mediated histone H3K9 hypermethylation in neurons worsens the neurological phenotype of Mecp2-deficient mice.Conserved higher-order chromatin regulates NMDA receptor gene expression and cognition.AGO2 and SETDB1 cooperate in promoter-targeted transcriptional silencing of the androgen receptor gene.Activation of DNA damage response signaling by condensed chromatin.Profiling the substrate specificity of protein kinases by on-bead screening of peptide librariesAdenovirus small E1A employs the lysine acetylases p300/CBP and tumor suppressor Rb to repress select host genes and promote productive virus infection.The three-dimensional structure of human interphase chromosomes is related to the transcriptome map.How can satellite DNA divergence cause reproductive isolation? Let us count the chromosomal ways.Aberrant chromatin remodeling by retinoic acid receptor alpha fusion proteins assessed at the single-cell levelHeterochromatin protein 1alpha: a hallmark of cell proliferation relevant to clinical oncology.Dynamics of inherently bounded histone modification domainsPAD4 mediated histone hypercitrullination induces heterochromatin decondensation and chromatin unfolding to form neutrophil extracellular trap-like structures.Chromatin loops, gene positioning, and gene expression.Epigenetic Editing: targeted rewriting of epigenetic marks to modulate expression of selected target genes.Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR.Chromatin remodeling complexes interact dynamically with a glucocorticoid receptor-regulated promoterDynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin.RB1, development, and cancer.Chromatin condensation in terminally differentiating mouse erythroblasts does not involve special architectural proteins but depends on histone deacetylation.Chromatin dynamics is correlated with replication timing.Domains of heterochromatin protein 1 required for Drosophila melanogaster heterochromatin spreadingThe emerging role of HP1 in the DNA damage response.pRb, a local chromatin organizer with global possibilities.
P2860
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P2860
In vivo HP1 targeting causes large-scale chromatin condensation and enhanced histone lysine methylation
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
In vivo HP1 targeting causes l ...... ced histone lysine methylation
@ast
In vivo HP1 targeting causes l ...... ced histone lysine methylation
@en
In vivo HP1 targeting causes l ...... ced histone lysine methylation
@en-gb
In vivo HP1 targeting causes l ...... ced histone lysine methylation
@nl
type
label
In vivo HP1 targeting causes l ...... ced histone lysine methylation
@ast
In vivo HP1 targeting causes l ...... ced histone lysine methylation
@en
In vivo HP1 targeting causes l ...... ced histone lysine methylation
@en-gb
In vivo HP1 targeting causes l ...... ced histone lysine methylation
@nl
prefLabel
In vivo HP1 targeting causes l ...... ced histone lysine methylation
@ast
In vivo HP1 targeting causes l ...... ced histone lysine methylation
@en
In vivo HP1 targeting causes l ...... ced histone lysine methylation
@en-gb
In vivo HP1 targeting causes l ...... ced histone lysine methylation
@nl
P2093
P2860
P3181
P1476
In vivo HP1 targeting causes l ...... ced histone lysine methylation
@en
P2093
Andrew S Belmont
Anne E Carpenter
Ineke van der Kraan
Johan van der Vlag
Pernette J Verschure
Roel van Driel
Wim de Leeuw
P2860
P304
P3181
P356
10.1128/MCB.25.11.4552-4564.2005
P407
P577
2005-06-01T00:00:00Z