The nuclear receptor NR2E3 plays a role in human retinal photoreceptor differentiation and degeneration
about
Recessive NRL mutations in patients with clumped pigmentary retinal degeneration and relative preservation of blue cone functionAn Arg311Gln NR2E3 mutation in a family with classic Goldmann-Favre syndromeIdentification of regulatory targets of tissue-specific transcription factors: application to retina-specific gene regulation.A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-cone syndrome.Minireview: the role of nuclear receptors in photoreceptor differentiation and diseasegdf6a is required for cone photoreceptor subtype differentiation and for the actions of tbx2b in determining rod versus cone photoreceptor fateThe Crystal Structure of the Orphan Nuclear Receptor NR2E3/PNR Ligand Binding Domain Reveals a Dimeric Auto-Repressed ConformationBiology and therapy of inherited retinal degenerative disease: insights from mouse modelsA cell cycle-dependent co-repressor mediates photoreceptor cell-specific nuclear receptor functionCloning and characterization of mr-s, a novel SAM domain protein, predominantly expressed in retinal photoreceptor cellsThe photoreceptor-specific nuclear receptor Nr2e3 interacts with Crx and exerts opposing effects on the transcription of rod versus cone genesPotential of Small Molecule-Mediated Reprogramming of Rod Photoreceptors to Treat Retinitis PigmentosaCausal variants screened by whole exome sequencing in a patient with maternal uniparental isodisomy of chromosome 10 and a complicated phenotype.Defective photoreceptor phagocytosis in a mouse model of enhanced S-cone syndrome causes progressive retinal degeneration.Serial sectioning for examination of photoreceptor cell architecture by focused ion beam technology.Analysis of C. elegans NR2E nuclear receptors defines three conserved clades and ligand-independent functions.Sterile alpha motif containing 7 (samd7) is a novel crx-regulated transcriptional repressor in the retina.Structure of cone photoreceptors.Mutations in the DNA-binding domain of NR2E3 affect in vivo dimerization and interaction with CRX.Nuclear receptor unfulfilled regulates axonal guidance and cell identity of Drosophila mushroom body neurons.Engineering retina from human retinal progenitors (cell lines).The association between nuclear receptors and ocular diseasesThe nuclear receptor gene family in the Pacific oyster, Crassostrea gigas, contains a novel subfamily groupRod photoreceptor differentiation in fetal and infant human retina.Neurogenin1 effectively reprograms cultured chick retinal pigment epithelial cells to differentiate toward photoreceptors.Abnormal distribution of red/green cone opsins in a patient with an autosomal dominant cone dystrophy.In pursuit of synthetic modulators for the orphan retina-specific nuclear receptor NR2E3The zebrafish pob gene encodes a novel protein required for survival of red cone photoreceptor cells.Developmental or degenerative--NR2E3 gene mutations in two patients with enhanced S cone syndrome.Disruption of the human cone photoreceptor mosaic from a defect in NR2E3 transcription factor function in young adults.In vivo function of the orphan nuclear receptor NR2E3 in establishing photoreceptor identity during mammalian retinal developmentExcess cones in the retinal degeneration rd7 mouse, caused by the loss of function of orphan nuclear receptor Nr2e3, originate from early-born photoreceptor precursorsExpanded clinical spectrum of enhanced S-cone syndromeA detailed phenotypic study of "cone dystrophy with supernormal rod ERG".Cone-like morphological, molecular, and electrophysiological features of the photoreceptors of the Nrl knockout mouse.Deregulation of NR2E3, an orphan nuclear receptor, by benzo(a)pyrene-induced oxidative stress is associated with histone modification status change of the estrogen receptor gene promoter.Clinical disorders affecting mesopic vision.Choroideremia: analysis of the retina from a female symptomatic carrier.Retinal Remodeling and Metabolic Alterations in Human AMD.Retinal pathology of a patient with Goldmann-Favre syndrome
P2860
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P2860
The nuclear receptor NR2E3 plays a role in human retinal photoreceptor differentiation and degeneration
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The nuclear receptor NR2E3 pla ...... fferentiation and degeneration
@ast
The nuclear receptor NR2E3 pla ...... fferentiation and degeneration
@en
The nuclear receptor NR2E3 pla ...... fferentiation and degeneration
@en-gb
The nuclear receptor NR2E3 pla ...... fferentiation and degeneration
@nl
type
label
The nuclear receptor NR2E3 pla ...... fferentiation and degeneration
@ast
The nuclear receptor NR2E3 pla ...... fferentiation and degeneration
@en
The nuclear receptor NR2E3 pla ...... fferentiation and degeneration
@en-gb
The nuclear receptor NR2E3 pla ...... fferentiation and degeneration
@nl
prefLabel
The nuclear receptor NR2E3 pla ...... fferentiation and degeneration
@ast
The nuclear receptor NR2E3 pla ...... fferentiation and degeneration
@en
The nuclear receptor NR2E3 pla ...... fferentiation and degeneration
@en-gb
The nuclear receptor NR2E3 pla ...... fferentiation and degeneration
@nl
P2093
P2860
P50
P3181
P356
P1476
The nuclear receptor NR2E3 pla ...... fferentiation and degeneration
@en
P2093
Alan F Wright
Ann H Milam
Artur V Cideciyan
Linda Rose
Mark R Barakat
Nisha Gupta
Tomas S Aleman
Wai-Xing Tang
P2860
P304
P3181
P356
10.1073/PNAS.022533099
P407
P577
2002-01-02T00:00:00Z