Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex - Wikidata - wikimedia - TriplyDB

Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex

Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex

http://www.wikidata.org/entity/Q24532403

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Identification of the Wnt signaling activator leucine-rich repeat in Flightless interaction protein 2 by a genome-wide functional analysis Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex CK2 phosphorylation of the armadillo repeat region of beta-catenin potentiates Wnt signaling beta-Catenin is a Nek2 substrate involved in centrosome separation.Identification of a novel Wnt5a-CK1ɛ-Dvl2-Plk1-mediated primary cilia disassembly pathway GSK-3: tricks of the trade for a multi-tasking kinase Wnt signaling: the good and the bad PGF2alpha induced differential expression of genes involved in turnover of extracellular matrix in rat decidual cells Stabilization of beta-catenin by a Wnt-independent mechanism regulates cardiomyocyte growth Axin utilizes distinct regions for competitive MEKK1 and MEKK4 binding and JNK activation Casein kinase I epsilon enhances the binding of Dvl-1 to Frat-1 and is essential for Wnt-3a-induced accumulation of beta-catenin Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway The DIX domain protein coiled-coil-DIX1 inhibits c-Jun N-terminal kinase activation by Axin and dishevelled through distinct mechanisms Interactions between Casein kinase Iepsilon (CKIepsilon) and two substrates from disparate signaling pathways reveal mechanisms for substrate-kinase specificity Naked1 antagonizes Wnt signaling by preventing nuclear accumulation of β-catenin The antihelmintic drug pyrvinium pamoate targets aggressive breast cancer Casein kinase Iepsilon modulates the signaling specificities of dishevelled Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin Nek2 phosphorylates and stabilizes β-catenin at mitotic centrosomes downstream of Plk1.IC261 induces cell cycle arrest and apoptosis of human cancer cells via CK1δ/ɛ and Wnt/β-catenin independent inhibition of mitotic spindle formation.Deletion of RTS1, encoding a regulatory subunit of protein phosphatase 2A, results in constitutive amino acid signaling via increased Stp1p processing Identification of a novel conserved mixed-isoform B56 regulatory subunit and spatiotemporal regulation of protein phosphatase 2A during Xenopus laevis development.Selective inhibition of IFNG-induced autophagy by Mir155- and Mir31-responsive WNT5A and SHH signaling HER2 in Breast Cancer Stemness: A Negative Feedback Loop towards Trastuzumab Resistance.Adeno-sh-beta-catenin abolishes ischemic preconditioning-mediated cardioprotection by downregulation of its target genes VEGF, Bcl-2, and survivin in ischemic rat myocardium.An opposite role for tau in circadian rhythms revealed by mathematical modeling A c-Myc activation sensor-based high-throughput drug screening identifies an antineoplastic effect of nitazoxanide.Association of genetic variation in genes implicated in the beta-catenin destruction complex with risk of breast cancer.Secreted Frizzled-related proteins: searching for relationships and patterns.The ins and outs of APC and beta-catenin nuclear transport.Astrocyte elevated gene-1(AEG-1) induces epithelial-mesenchymal transition in lung cancer through activating Wnt/β-catenin signaling Phosphatases: the new brakes for cancer development?The first armadillo repeat is involved in the recognition and regulation of beta-catenin phosphorylation by protein kinase CK1 Viruses and cancer: lessons from the human polyomavirus, JCV.Physiological roles of glycogen synthase kinase-3: potential as a therapeutic target for diabetes and other disorders.Casein kinase I delta controls centrosome positioning during T cell activation The many faces of beta-TrCP E3 ubiquitin ligases: reflections in the magic mirror of cancer.A Comprehensive Overview of Skeletal Phenotypes Associated with Alterations in Wnt/β-catenin Signaling in Humans and Mice.Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo.Casein kinase 1 is a novel negative regulator of E-cadherin-based cell-cell contacts.

P2860

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P2860

Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex

http://www.wikidata.org/entity/Q24532403

description

2002 nî lūn-bûn

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2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի փետրվարին հրատարակված գիտական հոդված

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2002年の論文

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2002年学术文章

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2002年学术文章

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2002年学术文章

@zh-hans

2002年学术文章

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2002年学术文章

@zh-sg

2002年學術文章

@yue

name

Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex

@ast

Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex

@en

Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex

@en-gb

Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex

@nl

type

label

Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex

@ast

Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex

@en

Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex

@en-gb

Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex

@nl

prefLabel

Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex

@ast

Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex

@en

Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex

@en-gb

Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex

@nl

P1433

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P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex

@en

P2093

April Yochum

http://www.w3.org/2001/XMLSchema#string

Joni M Seeling

http://www.w3.org/2001/XMLSchema#string

Virginia Hill

http://www.w3.org/2001/XMLSchema#string

Zhong-Hua Gao

http://www.w3.org/2001/XMLSchema#string

P2860

GSK-3beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin

Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon

Casein kinase iepsilon in the wnt pathway: regulation of beta-catenin function

Crystal structure of a conformation-selective casein kinase-1 inhibitor

Wnt signaling and cancer

PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling

Inhibition of the Wnt signaling pathway by the PR61 subunit of protein phosphatase 2A

Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins

Assignment of human protein phosphatase 2A regulatory subunit genes b56alpha, b56beta, b56gamma, b56delta, and b56epsilon (PPP2R5A-PPP2R5E), highly expressed in muscle and brain, to chromosome regions 1q41, 11q12, 3p21, 6p21.1, and 7p11.2 --> p12

Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain

P304

1182-1187

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P31

scholarly article

P3181

449994

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P356

10.1073/PNAS.032468199

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P407

P433

3

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P478

99

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P50

David M. Virshup

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2002-01-29T00:00:00Z

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P5875

11540632

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P698

11818547

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation

P932

122164

http://www.w3.org/2001/XMLSchema#string