Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2 - Wikidata - wikimedia - TriplyDB

Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2

Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2

http://www.wikidata.org/entity/Q24534641

about

Upstream regulatory role for XIAP in receptor-mediated apoptosis The mitochondrial ARTS protein promotes apoptosis through targeting XIAP Irod/Ian5: an inhibitor of gamma-radiation- and okadaic acid-induced apoptosis BcR-induced apoptosis involves differential regulation of C16 and C24-ceramide formation and sphingolipid-dependent activation of the proteasome Critical upstream signals of cytochrome C release induced by a novel Bcl-2 inhibitor Ectopic expression of new alternative splice variant of Smac/DIABLO increases mammospheres formation Mono- or double-site phosphorylation distinctly regulates the proapoptotic function of Bax Effects of Ranolazine on Astrocytes and Neurons in Primary Culture Biofabrication of a novel biomolecule-assisted reduced graphene oxide: an excellent biocompatible nanomaterial Different mitochondrial intermembrane space proteins are released during apoptosis in a manner that is coordinately initiated but can vary in duration.Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes.Heat shock pretreatment inhibited the release of Smac/DIABLO from mitochondria and apoptosis induced by hydrogen peroxide in cardiomyocytes and C2C12 myogenic cells.Mannheimia haemolytica leukotoxin induces apoptosis of bovine lymphoblastoid cells (BL-3) via a caspase-9-dependent mitochondrial pathway.Metalloproteinase dependent reduction of cell surface cluster determinants upon the induction of apoptosis.Potential therapeutic benefits of strategies directed to mitochondria.Small-molecule Bax agonists for cancer therapy.Glutamate induces mitochondrial dynamic imbalance and autophagy activation: preventive effects of selenium.Inhibition of pluripotent stem cell-derived teratoma formation by small molecules Synergistic induction of cell death in liver tumor cells by TRAIL and chemotherapeutic drugs via the BH3-only proteins Bim and Bid Amyloid-Beta interaction with mitochondria The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet.Molecular mechanisms of irradiation-induced apoptosis Bcl-2 inhibitor HA14-1 and genistein together adeptly down regulated survival factors and activated cysteine proteases for apoptosis in human malignant neuroblastoma SK-N-BE2 and SH-SY5Y cells c-Jun NH2-terminal kinase-mediated signaling is essential for Pseudomonas aeruginosa ExoS-induced apoptosis.Cell stress-associated caspase activation: intrinsically complex?Intervertebral disc degeneration: the role of the mitochondrial pathway in annulus fibrosus cell apoptosis induced by overload.Signaling of cell death and cell survival following focal cerebral ischemia: life and death struggle in the penumbra.Antagonism of cytotoxic chemotherapy in neuroblastoma cell lines by 13-cis-retinoic acid is mediated by the antiapoptotic Bcl-2 family proteins Osmostress-induced apoptosis in Xenopus oocytes: role of stress protein kinases, calpains and Smac/DIABLO.SapC-DOPS nanovesicles induce Smac- and Bax-dependent apoptosis through mitochondrial activation in neuroblastomas.Initiation but no execution - modulation of peripheral blood lymphocyte apoptosis in rheumatoid arthritis - a potential role for heat shock protein 70.Activation of K+ channels: an essential pathway in programmed cell death.Targeting mitochondrial factor Smac/DIABLO as therapy for multiple myeloma (MM)Human herpesvirus 6A induces apoptosis of primary human fetal astrocytes via both caspase-dependent and -independent pathways The IAP-antagonist ARTS initiates caspase activation upstream of cytochrome C and SMAC/Diablo.Synergistic exacerbation of mitochondrial and synaptic dysfunction and resultant learning and memory deficit in a mouse model of diabetic Alzheimer's disease.Bak Conformational Changes Induced by Ligand Binding: Insight into BH3 Domain Binding and Bak Homo-Oligomerization Tissue Inhibitor of Metalloproteinase-4 Triggers Apoptosis in Cervical Cancer Cells.Targeting endogenous inhibitors of apoptosis for treatment of cancer, stroke and multiple sclerosis.The Smac mimetic RMT5265.2HCL induces apoptosis in EBV and HTLV-I associated lymphoma cells by inhibiting XIAP and promoting the mitochondrial release of cytochrome C and Smac.

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P2860

Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2

http://www.wikidata.org/entity/Q24534641

description

2001 nî lūn-bûn

@nan

2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2001年の論文

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2001年論文

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2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

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2001年論文

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2001年论文

@wuu

name

Apoptosis-associated release o ...... spases and is blocked by Bcl-2

@ast

Apoptosis-associated release o ...... spases and is blocked by Bcl-2

@en

Apoptosis-associated release o ...... spases and is blocked by Bcl-2

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Apoptosis-associated release o ...... spases and is blocked by Bcl-2

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type

label

Apoptosis-associated release o ...... spases and is blocked by Bcl-2

@ast

Apoptosis-associated release o ...... spases and is blocked by Bcl-2

@en

Apoptosis-associated release o ...... spases and is blocked by Bcl-2

@en-gb

Apoptosis-associated release o ...... spases and is blocked by Bcl-2

@nl

prefLabel

Apoptosis-associated release o ...... spases and is blocked by Bcl-2

@ast

Apoptosis-associated release o ...... spases and is blocked by Bcl-2

@en

Apoptosis-associated release o ...... spases and is blocked by Bcl-2

@en-gb

Apoptosis-associated release o ...... spases and is blocked by Bcl-2

@nl

P1433

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P1433

The EMBO Journal

P1476

Apoptosis-associated release o ...... spases and is blocked by Bcl-2

@en

P2093

S J Martin

http://www.w3.org/2001/XMLSchema#string

P2860

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria

tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

P304

6627-6636

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scholarly article

P356

10.1093/EMBOJ/20.23.6627

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23

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P478

20

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2001-12-01T00:00:00Z

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11628379

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P698

11726499

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P921

apoptotic process

P932

125329

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