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Conserved CTCF insulator elements flank the mouse and human beta-globin loci

Conserved CTCF insulator elements flank the mouse and human beta-globin loci

http://www.wikidata.org/entity/Q24537420

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CHD8 associates with human Staf and contributes to efficient U6 RNA polymerase III transcription Heterogeneous nuclear ribonucleoprotein C1/C2, MeCP1, and SWI/SNF form a chromatin remodeling complex at the beta-globin locus control region The insulation of genes from external enhancers and silencing chromatin.CTCF: master weaver of the genome Locus control regions CTCF binds the proximal exonic region of hTERT and inhibits its transcription.An Overview of Genome Organization and How We Got There: from FISH to Hi-C The complex transcription regulatory landscape of our genome: control in three dimensions CTCF: the protein, the binding partners, the binding sites and their chromatin loops Insulators: exploiting transcriptional and epigenetic mechanisms Chromosome Conformation Capture Carbon Copy (5C): a massively parallel solution for mapping interactions between genomic elements Epigenetic boundaries of tumour suppressor gene promoters: the CTCF connection and its role in carcinogenesis The human enhancer blocker CTC-binding factor interacts with the transcription factor Kaiso CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus 5'HS5 of the human beta-globin locus control region is dispensable for the formation of the beta-globin active chromatin hub.Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster Cell type specificity of chromatin organization mediated by CTCF and cohesin.Evidence that DNase I hypersensitive site 5 of the human beta-globin locus control region functions as a chromosomal insulator in transgenic mice Genomic imprinting recapitulated in the human beta-globin locus.Evaluation of regulatory potential and conservation scores for detecting cis-regulatory modules in aligned mammalian genome sequences.CTCF controls expression and chromatin architecture of the human major histocompatibility complex class II locus.GeSICA: genome segmentation from intra-chromosomal associations.Nuclear matrix interactions at the human protamine domain: a working model of potentiation.Mutation of a barrier insulator in the human ankyrin-1 gene is associated with hereditary spherocytosis Replication and transcription: shaping the landscape of the genome.Multiple interactions between regulatory regions are required to stabilize an active chromatin hub.The 5'-HS4 chicken beta-globin insulator is a CTCF-dependent nuclear matrix-associated element Chromosome organization and chromatin modification: influence on genome function and evolution.Active chromatin hub of the mouse alpha-globin locus forms in a transcription factory of clustered housekeeping genes Differential nuclear scaffold/matrix attachment marks expressed genes.Cohesin mediates chromatin interactions that regulate mammalian β-globin expression Human beta-globin locus control region HS5 contains CTCF- and developmental stage-dependent enhancer-blocking activity in erythroid cells.Replication of the chicken beta-globin locus: early-firing origins at the 5' HS4 insulator and the rho- and betaA-globin genes show opposite epigenetic modifications.A complex chromatin landscape revealed by patterns of nuclease sensitivity and histone modification within the mouse beta-globin locus Communication over a large distance: enhancers and insulators.CCCTC-binding factor recruitment to the early region of the human papillomavirus 18 genome regulates viral oncogene expression.Distinctive signatures of histone methylation in transcribed coding and noncoding human beta-globin sequences Linear distance from the locus control region determines epsilon-globin transcriptional activity.A facilitated tracking and transcription mechanism of long-range enhancer function.Remote control of gene transcription.

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Conserved CTCF insulator elements flank the mouse and human beta-globin loci

http://www.wikidata.org/entity/Q24537420

description

2002 nî lūn-bûn

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2002 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի հունիսին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

Conserved CTCF insulator elements flank the mouse and human beta-globin loci

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Conserved CTCF insulator elements flank the mouse and human beta-globin loci

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Conserved CTCF insulator elements flank the mouse and human beta-globin loci

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type

label

Conserved CTCF insulator elements flank the mouse and human beta-globin loci

@ast

Conserved CTCF insulator elements flank the mouse and human beta-globin loci

@en

Conserved CTCF insulator elements flank the mouse and human beta-globin loci

@nl

prefLabel

Conserved CTCF insulator elements flank the mouse and human beta-globin loci

@ast

Conserved CTCF insulator elements flank the mouse and human beta-globin loci

@en

Conserved CTCF insulator elements flank the mouse and human beta-globin loci

@nl

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MCB.22.11.3820-3831.2002

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Molecular and Cellular Biology

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Conserved CTCF insulator elements flank the mouse and human beta-globin loci

@en

P2093

Catherine M Farrell

http://www.w3.org/2001/XMLSchema#string

Gary Felsenfeld

http://www.w3.org/2001/XMLSchema#string

P2860

Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters

An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes

The "beta-like-globin" gene domain in human erythroid cells

Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes

The protein CTCF is required for the enhancer blocking activity of vertebrate insulators

CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease

Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci

The locus control region is necessary for gene expression in the human beta-globin locus but not the maintenance of an open chromatin structure in erythroid cells.

Looping, linking, and chromatin activity: new insights into beta-globin locus regulation.

An insulator element and condensed chromatin region separate the chicken beta-globin locus from an independently regulated erythroid-specific folate receptor gene

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3820-3831

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3761040

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10.1128/MCB.22.11.3820-3831.2002

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