Impaired binding of standard initiation factors mediates poliovirus translation attenuation.
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Extracellular RNA is a natural cofactor for the (auto-)activation of Factor VII-activating protease (FSAP)Functional analysis of RNA structures present at the 3' extremity of the murine norovirus genome: the variable polypyrimidine tract plays a role in viral virulencemicroRNA-122 stimulates translation of hepatitis C virus RNAThe Hepatitis C Virus RNA 3'-Untranslated Region Strongly Enhances Translation Directed by the Internal Ribosome Entry SiteGlycyl-tRNA synthetase specifically binds to the poliovirus IRES to activate translation initiationGenetic determinants of cell type-specific poliovirus propagation in HEK 293 cells.Oncolytic polio virotherapy of cancerFoot-and-mouth disease.Induction of viral, 7-methyl-guanosine cap-independent translation and oncolysis by mitogen-activated protein kinase-interacting kinase-mediated effects on the serine/arginine-rich protein kinase.HIV-1 transcripts use IRES-initiation under conditions where Cap-dependent translation is restricted by poliovirus 2A proteaseA mouse-adapted enterovirus 71 strain causes neurological disease in mice after oral infection.Attenuation of neurovirulence, biodistribution, and shedding of a poliovirus:rhinovirus chimera after intrathalamic inoculation in Macaca fascicularis.Poly(rC) binding proteins and the 5' cloverleaf of uncapped poliovirus mRNA function during de novo assembly of polysomesRibosomal Initiation Complex Assembly within the Wild-Strain of Coxsackievirus B3 and Live-Attenuated Sabin3-like IRESes during the Initiation of TranslationDirect functional interaction of initiation factor eIF4G with type 1 internal ribosomal entry sitesMolecular mechanisms of attenuation of the Sabin strain of poliovirus type 3.Attenuating mutations in coxsackievirus B3 map to a conformational epitope that comprises the puff region of VP2 and the knob of VP3.Role of RNA structure motifs in IRES-dependent translation initiation of the coxsackievirus B3: new insights for developing live-attenuated strains for vaccines and gene therapy.Poliovirus switches to an eIF2-independent mode of translation during infection.Cytotoxic and immunogenic mechanisms of recombinant oncolytic poliovirusA morpholino oligomer targeting highly conserved internal ribosome entry site sequence is able to inhibit multiple species of picornavirus.In vitro molecular characterization of RNA-proteins interactions during initiation of translation of a wild-type and a mutant Coxsackievirus B3 RNAs.Nucleobase but not Sugar Fidelity is Maintained in the Sabin I RNA-Dependent RNA Polymerase.In vitro-reduced translation efficiency of coxsackievirus B3 Sabin3-like strain is correlated to impaired binding of cellular initiation factors to viral IRES RNA.A positively charged cluster in the epidermal growth factor-like domain of Factor VII-activating protease (FSAP) is essential for polyanion binding.Evidence for an RNA chaperone function of polypyrimidine tract-binding protein in picornavirus translationA novel mechanism of eukaryotic translation initiation that is neither m7G-cap-, nor IRES-dependent.Impaired binding of standard initiation factors eIF3b, eIF4G and eIF4B to domain V of the live-attenuated coxsackievirus B3 Sabin3-like IRES--alternatives for 5'UTR-related cardiovirulence mechanisms.Picornavirus internal ribosome entry site elements can stimulate translation of upstream genes.Effects of vaccine strain mutations in domain V of the internal ribosome entry segment compared in the wild type poliovirus type 1 context.Recombinant Poliovirus for Cancer Immunotherapy.
P2860
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P2860
Impaired binding of standard initiation factors mediates poliovirus translation attenuation.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Impaired binding of standard i ...... ovirus translation attenuation
@nl
Impaired binding of standard i ...... virus translation attenuation.
@ast
Impaired binding of standard i ...... virus translation attenuation.
@en
type
label
Impaired binding of standard i ...... ovirus translation attenuation
@nl
Impaired binding of standard i ...... virus translation attenuation.
@ast
Impaired binding of standard i ...... virus translation attenuation.
@en
altLabel
Impaired Binding of Standard I ...... ovirus Translation Attenuation
@en
prefLabel
Impaired binding of standard i ...... ovirus translation attenuation
@nl
Impaired binding of standard i ...... virus translation attenuation.
@ast
Impaired binding of standard i ...... virus translation attenuation.
@en
P2093
P2860
P1433
P1476
Impaired binding of standard i ...... virus translation attenuation.
@en
P2093
Amandus Zeller
Anja Sonntag
Gergis Bassili
Kerstin Ochs
Lanja Saleh
Michael Niepmann
Yutong Song
P2860
P304
P356
10.1128/JVI.77.1.115-122.2003
P407
P577
2003-01-01T00:00:00Z