Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2.
about
Prospects for Improving Brain Function in Individuals with Down SyndromeCalmodulin-kinases: modulators of neuronal development and plasticityEph/ephrin molecules--a hub for signaling and endocytosisNumb links extracellular cues to intracellular polarity machinery to promote chemotaxisEmerging roles for intersectin (ITSN) in regulating signaling and disease pathwaysEphBs: an integral link between synaptic function and synaptopathiesLead exposure disrupts global DNA methylation in human embryonic stem cells and alters their neuronal differentiationPostnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic nicheCdc42 GTPase-activating protein (CdGAP) interacts with the SH3D domain of Intersectin through a novel basic-rich motifN-wasp and the arp2/3 complex are critical regulators of actin in the development of dendritic spines and synapsesPhosphorylation of Numb regulates its interaction with the clathrin-associated adaptor AP-2Dysbindin-1, WAVE2 and Abi-1 form a complex that regulates dendritic spine formationEphrin-A5 and EphA5 interaction induces synaptogenesis during early hippocampal developmentRho-GTPase-activating protein interacting with Cdc-42-interacting protein 4 homolog 2 (Rich2): a new Ras-related C3 botulinum toxin substrate 1 (Rac1) GTPase-activating protein that controls dendritic spine morphogenesisRegulation of neuron survival through an intersectin-phosphoinositide 3'-kinase C2beta-AKT pathwayAdaptor proteins intersectin 1 and 2 bind similar proline-rich ligands but are differentially recognized by SH2 domain-containing proteinsAutoinhibition of GEF activity in Intersectin 1 is mediated by the short SH3-DH domain linker.Role of the C-terminal SH3 domain and N-terminal tyrosine phosphorylation in regulation of Tim and related Dbl-family proteinsNumb deficiency in cerebellar Purkinje cells impairs synaptic expression of metabotropic glutamate receptor and motor coordination.Tiam-Rac signaling mediates trans-endocytosis of ephrin receptor EphB2 and is important for cell repulsion.Protein profiles in Tc1 mice implicate novel pathway perturbations in the Down syndrome brainTwo novel human NUMB isoforms provide a potential link between development and cancer.Intersecting pathways in cell biologyControl of synapse development and plasticity by Rho GTPase regulatory proteins.Cortical abnormalities and non-spatial learning deficits in a mouse model of CranioFrontoNasal syndrome.Protein dynamics associated with failed and rescued learning in the Ts65Dn mouse model of Down syndrome.Infralimbic EphB2 Modulates Fear Extinction in Adolescent Rats.Maternal infection leads to abnormal gene regulation and brain atrophy in mouse offspring: implications for genesis of neurodevelopmental disordersThe E3 ligase Mind bomb-1 (Mib1) modulates Delta-Notch signaling to control neurogenesis and gliogenesis in the developing spinal cord.Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylation.Eph/ephrin signaling: networks.Intersectin: The Crossroad between Vesicle Exocytosis and Endocytosis.Molecular responses of the Ts65Dn and Ts1Cje mouse models of Down syndrome to MK-801.ITSN-1 controls vesicle recycling at the neuromuscular junction and functions in parallel with DAB-1.Numb-mediated neurite outgrowth is isoform-dependent, and requires activation of voltage-dependent calcium channels.Protein profiles associated with context fear conditioning and their modulation by memantine.The Ca2+ and Rho GTPase signaling pathways underlying activity-dependent actin remodeling at dendritic spines.Numb and Alzheimer's disease: the current pictureDendritic spines: the locus of structural and functional plasticity.Intersectin scaffold proteins and their role in cell signaling and endocytosis.
P2860
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P2860
Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2
@nl
Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2.
@ast
Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2.
@en
type
label
Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2
@nl
Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2.
@ast
Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2.
@en
prefLabel
Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2
@nl
Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2.
@ast
Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2.
@en
P2093
P2860
P50
P356
P1476
Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2.
@en
P2093
Akihiro Iwamatsu
Akinori Tokunaga
Akitoshi Hara
Katsuhiro Kato
Kozo Kaibuchi
Tomonari Hamaguchi
Tomoya Yamaguchi
P2860
P304
P356
10.1091/MBC.E05-07-0700
P407
P577
2006-01-04T00:00:00Z