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PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

http://www.wikidata.org/entity/Q24541524

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Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice Regulation of hepatic ApoC3 expression by PGC-1β mediates hypolipidemic effect of nicotinic acid Moonlighting function of glycerol kinase causes systems-level changes in rat hepatoma cells FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response SCFCdc4 acts antagonistically to the PGC-1alpha transcriptional coactivator by targeting it for ubiquitin-mediated proteolysis Orphan nuclear receptor estrogen-related receptor alpha is essential for adaptive thermogenesis Thioredoxin and ventricular remodeling Resveratrol and Myopathy Role of BAF60a/BAF60c in chromatin remodeling and hepatic lipid metabolism Nuclear receptors and AMPK: can exercise mimetics cure diabetes?Role of Energy Metabolism in the Brown Fat Gene Program The mitochondria in diabetic heart failure: from pathogenesis to therapeutic promise Parkinson's disease, insulin resistance and novel agents of neuroprotection Transcriptional integration of mitochondrial biogenesis CAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-α-Gabpa and stress-induced adaptive responses via NF-κB-cMYC PGC-1/Spargel Counteracts High-Fat-Diet-Induced Obesity and Cardiac Lipotoxicity Downstream of TOR and Brummer ATGL Lipase.SRC-2 coactivator deficiency decreases functional reserve in response to pressure overload of mouse heart Postnatal muscle modification by myogenic factors modulates neuropathology and survival in an ALS mouse model Communication between the ERRalpha homodimer interface and the PGC-1alpha binding surface via the helix 8-9 loop Function of the SIRT3 mitochondrial deacetylase in cellular physiology, cancer, and neurodegenerative disease Beneficial role of bitter melon supplementation in obesity and related complications in metabolic syndrome Revisiting the adipocyte: a model for integration of cytokine signaling in the regulation of energy metabolism Redox signaling in skeletal muscle: role of aging and exercise Transcriptional regulation of the human hepatic lipase (LIPC) gene promoter Alternate day fasting impacts the brain insulin-signaling pathway of young adult male C57BL/6 mice Mitochondrial dysfunction in diabetic cardiomyopathy Metformin reduces hepatic expression of SIRT3, the mitochondrial deacetylase controlling energy metabolism Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha Downregulation of nuclear-encoded genes of oxidative metabolism in dialyzed chronic kidney disease patients Protective effects of myricetin on acute hypoxia-induced exercise intolerance and mitochondrial impairments in rats Acute exercise modulates the Foxo1/PGC-1alpha pathway in the liver of diet-induced obesity rats Regulation of pyruvate dehydrogenase kinase 4 (PDK4) by thyroid hormone: role of the peroxisome proliferator-activated receptor gamma coactivator (PGC-1 alpha)PGC-1alpha coactivates estrogen-related receptor-alpha to induce the expression of glucokinase Role of sirtuin 1 in the regulation of hepatic gene expression by thyroid hormone Novel small-molecule PGC-1α transcriptional regulator with beneficial effects on diabetic db/db mice PGC-1 alpha serine 570 phosphorylation and GCN5-mediated acetylation by angiotensin II drive catalase down-regulation and vascular hypertrophy

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PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

http://www.wikidata.org/entity/Q24541524

description

2006 nî lūn-bûn

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2006 թուականի Մարտին հրատարակուած գիտական յօդուած

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2006 թվականի մարտին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

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PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

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PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

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type

label

PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

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PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

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PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

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prefLabel

PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

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PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

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PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

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Journal of Clinical Investigation

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PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

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Brian N Finck

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Daniel P Kelly

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P2860

A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen

PGC-1, a versatile coactivator

The PGC-1-related protein PERC is a selective coactivator of estrogen receptor alpha

Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator

Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha

AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation.

Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells

Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK

Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha) regulates triglyceride metabolism by activation of the nuclear receptor FXR

Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscle

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615-22

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684801

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10.1172/JCI27794

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3

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116

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16511594

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1386111

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