p59OASL, a 2'-5' oligoadenylate synthetase like protein: a novel human gene related to the 2'-5' oligoadenylate synthetase family
about
The 100-kDa 2',5'-oligoadenylate synthetase catalyzing preferentially the synthesis of dimeric pppA2'p5'A molecules is composed of three homologous domainsThe nature of the catalytic domain of 2'-5'-oligoadenylate synthetasesInhibition of 2'-5' oligoadenylate synthetase by divalent metal ionsCharacterization of the 2'-5'-oligoadenylate synthetase ubiquitin-like familyViral encounters with 2',5'-oligoadenylate synthetase and RNase L during the interferon antiviral responseModification by ubiquitin-like proteins: significance in apoptosis and autophagy pathwaysPositional cloning of the murine flavivirus resistance geneRNase L plays a role in the antiviral response to West Nile virus.Dengue Virus Induces Novel Changes in Gene Expression of Human Umbilical Vein Endothelial CellsSequence and structure evolved separately in a ribosomal ubiquitin variantInteraction between the 2'-5' oligoadenylate synthetase-like protein p59 OASL and the transcriptional repressor methyl CpG-binding protein 1The Flvr-encoded murine oligoadenylate synthetase 1b (Oas1b) suppresses 2-5A synthesis in intact cellsMice deficient in oocyte-specific oligoadenylate synthetase-like protein OAS1D display reduced fertilityGlucocorticoid-attenuated response genes induced in the lung during endotoxemia.Expression and characterization of recombinant 2',5'-oligoadenylate synthetase from the marine sponge Geodia cydonium.Interferon-Inducible Oligoadenylate Synthetase-Like Protein Acts as an Antiviral Effector against Classical Swine Fever Virus via the MDA5-Mediated Type I Interferon-Signaling Pathway.Viral phosphodiesterases that antagonize double-stranded RNA signaling to RNase L by degrading 2-5AExpansion and molecular evolution of the interferon-induced 2'-5' oligoadenylate synthetase gene family.Oxymetholone therapy of fanconi anemia suppresses osteopontin transcription and induces hematopoietic stem cell cycling.Overlapping Patterns of Rapid Evolution in the Nucleic Acid Sensors cGAS and OAS1 Suggest a Common Mechanism of Pathogen Antagonism and Escape.Structural and functional analysis reveals that human OASL binds dsRNA to enhance RIG-I signalingEnzyme assays for synthesis and degradation of 2-5As and other 2'-5' oligonucleotides.Activation of Oas1a gene expression by type I IFN requires both STAT1 and STAT2 while only STAT2 is required for Oas1b activation.Defining the role of TRIP6 in cell physiology and cancer.The 2'-5'-oligoadenylate synthetase 3 enzyme potently synthesizes the 2'-5'-oligoadenylates required for RNase L activation.Identification of 2'-5'-Oligoadenylate Synthetase-Like Gene in Goose: Gene Structure, Expression Patterns, and Antiviral Activity Against Newcastle Disease Virus.Porcine 2', 5'-oligoadenylate synthetases inhibit Japanese encephalitis virus replication in vitro.Extracellular 2'-5' oligoadenylate synthetase stimulates RNase L-independent antiviral activity: a novel mechanism of virus-induced innate immunity.Association of the OAS3 rs1859330 G/A genetic polymorphism with severity of enterovirus-71 infection in Chinese Han children.Mitochondrial C11orf83 is a potent Antiviral Protein Independent of interferon production.2'-5'-Oligoadenylate Synthetase-Like Protein Inhibits Respiratory Syncytial Virus Replication and Is Targeted by the Viral Nonstructural Protein 1.Antiviral activity of human OASL protein is mediated by enhancing signaling of the RIG-I RNA sensorMicroarray-based gene expression analysis of hepatocellular carcinoma.Susceptibility to flavivirus-specific antiviral response of Oas1b affects the neurovirulence of the Far-Eastern subtype of tick-borne encephalitis virus.Origin of the interferon-inducible (2'-5')oligoadenylate synthetases: cloning of the (2'-5')oligoadenylate synthetase from the marine sponge Geodia cydonium.A novel ubiquitin-like domain in IkappaB kinase beta is required for functional activity of the kinase.The interferon-stimulated gene product oligoadenylate synthetase-like protein enhances replication of Kaposi's sarcoma-associated herpesvirus (KSHV) and interacts with the KSHV ORF20 protein.Increased expression of the type I interferon-inducible gene, lymphocyte antigen 6 complex locus E, in peripheral blood cells is predictive of lupus activity in a large cohort of Chinese lupus patients.Conserved Active-Site Residues Associated with OAS Enzyme Activity and Ubiquitin-Like Domains Are Not Required for the Antiviral Activity of goOASL Protein against Avian Tembusu VirusMolecular Cloning and Identification of the 2'-5' Oligoadenylate Synthetase 2 Gene in Chinese Domestic Pigs Through Bioinformatics Analysis, and Determination of Its Antiviral Activity Against Porcine Reproductive and Respiratory Syndrome Virus Infec
P2860
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P2860
p59OASL, a 2'-5' oligoadenylate synthetase like protein: a novel human gene related to the 2'-5' oligoadenylate synthetase family
description
1998 nî lūn-bûn
@nan
1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
p59OASL, a 2'-5' oligoadenylat ...... igoadenylate synthetase family
@ast
p59OASL, a 2'-5' oligoadenylat ...... igoadenylate synthetase family
@en
p59OASL, a 2'-5' oligoadenylat ...... igoadenylate synthetase family
@nl
type
label
p59OASL, a 2'-5' oligoadenylat ...... igoadenylate synthetase family
@ast
p59OASL, a 2'-5' oligoadenylat ...... igoadenylate synthetase family
@en
p59OASL, a 2'-5' oligoadenylat ...... igoadenylate synthetase family
@nl
prefLabel
p59OASL, a 2'-5' oligoadenylat ...... igoadenylate synthetase family
@ast
p59OASL, a 2'-5' oligoadenylat ...... igoadenylate synthetase family
@en
p59OASL, a 2'-5' oligoadenylat ...... igoadenylate synthetase family
@nl
P2093
P2860
P356
P1476
p59OASL, a 2'-5' oligoadenylat ...... igoadenylate synthetase family
@en
P2093
P2860
P304
P356
10.1093/NAR/26.18.4121
P407
P577
1998-09-15T00:00:00Z