Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase
about
The tumor suppressor Scrib interacts with the zyxin-related protein LPP, which shuttles between cell adhesion sites and the nucleusInactivation of p53 rescues the maintenance of high risk HPV DNA genomes deficient in expression of E6Thyrotropin receptor trafficking relies on the hScrib-betaPIX-GIT1-ARF6 pathwayThe mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherinProteolytic targeting of transcriptional regulator TIP120B by a HECT domain E3 ligaseHuman homolog of Drosophila tumor suppressor Scribble negatively regulates cell-cycle progression from G1 to S phase by localizing at the basolateral membrane in epithelial cellsAssociation of E6AP (UBE3A) with human papillomavirus type 11 E6 protein.hScrib interacts with ZO-2 at the cell-cell junctions of epithelial cellsRole of the PDZ domain-binding motif of the oncoprotein E6 in the pathogenesis of human papillomavirus type 31The HPV16 E6 binding protein Tip-1 interacts with ARHGEF16, which activates Cdc42Regulation of the discs large tumor suppressor by a phosphorylation-dependent interaction with the beta-TrCP ubiquitin ligase receptorThe hScrib/Dlg apico-basal control complex is differentially targeted by HPV-16 and HPV-18 E6 proteinsHuman scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coliDeregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinomaThe tumor suppressor Scrib selectively interacts with specific members of the zyxin family of proteinsScrib regulates PAK activity during the cell migration processDegradation of tyrosine phosphatase PTPN3 (PTPH1) by association with oncogenic human papillomavirus E6 proteins.MCC, a new interacting protein for Scrib, is required for cell migration in epithelial cellsThe global transcriptional effects of the human papillomavirus E6 protein in cervical carcinoma cell lines are mediated by the E6AP ubiquitin ligase.Human papillomavirus oncoprotein E6 inactivates the transcriptional coactivator human ADA3Analysis of the expression and localisation of a LAP protein, human scribble, in the normal and neoplastic epithelium of uterine cervixParkin-mediated monoubiquitination of the PDZ protein PICK1 regulates the activity of acid-sensing ion channelsViral Interactions with PDZ Domain-Containing Proteins-An Oncogenic Trait?Hepatitis C Virus Induces E6AP-Dependent Degradation of the Retinoblastoma ProteinLarge-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomesLano, a novel LAP protein directly connected to MAGUK proteins in epithelial cellsInteraction between Erbin and a Catenin-related protein in epithelial cellsThe ERBB2/HER2 receptor differentially interacts with ERBIN and PICK1 PSD-95/DLG/ZO-1 domain proteinshScrib is a functional homologue of the Drosophila tumour suppressor ScribbleAberrant overexpression of the cell polarity module scribble in human cancerHuman papillomavirus 16 E6 oncoprotein interferences with insulin signaling pathway by binding to tuberinThe tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edgeE3 ubiquitin ligase E6AP-mediated TSC2 turnover in the presence and absence of HPV16 E6HPV E6 and MAGUK protein interactions: determination of the molecular basis for specific protein recognition and degradationRequirement of PDZ-containing proteins for cell cycle regulation and differentiation in the mouse lens epitheliumDiscovery and confirmation of ligand binding specificities of the Schistosoma japonicum polarity protein ScribbleNectin4/PRR4, a new afadin-associated member of the nectin family that trans-interacts with nectin1/PRR1 through V domain interactionPDZ domain proteins: plug and play!Papillomavirus E6 oncoproteins.Papillomavirus E6 PDZ interactions can be replaced by repression of p53 to promote episomal human papillomavirus genome maintenance
P2860
Q21284172-EFAD1074-955C-4919-B5C4-F366EF1D7689Q21558774-55DB1355-7CF9-4816-9E98-1C9C11FAFE58Q24298340-A223C129-615D-431F-B56B-D7E08CB55EFBQ24298617-6D72B607-BB5B-4DCA-8879-56E4D443B12AQ24299749-9EE5D06A-F6D1-4E9F-AF6A-1CCD626AD8C2Q24302383-93A1671F-0C46-4B3D-ACC4-0EF9CFA3ED57Q24305966-32883D88-5029-44CF-A45E-942841ED78BFQ24306134-CB07AB56-8796-41B9-BE73-5702D81AAEC9Q24309432-7A17F85A-149E-45B1-A07B-1F44BE1D47F2Q24313916-E21C5B5F-A1DB-44B1-A844-398E9F004839Q24314190-92AC2E4E-7D1F-406A-85F5-D39666072185Q24315710-0D3C2324-4C60-408A-BD0C-21C524547738Q24317012-A39BA4FB-2DAF-4399-B353-157059FFBD05Q24319145-1F9785CC-87B2-400C-9F53-AF0576B046EBQ24319676-B7433185-E0BD-43D9-9853-8BC28E525EDBQ24328751-A29BC494-8BC4-4B72-8526-A030B87A7379Q24336493-2331A1BD-F7F8-4BCE-BB6C-7F9B1A7D695FQ24339374-A425C70E-82E2-4520-A39B-6927B2B5D211Q24521626-42D8A2DD-2F02-4991-855A-4DE128157B44Q24537722-7B3EF836-5341-44A7-AE5B-799D91174EC9Q24650342-068D3C0B-D421-4C49-9677-CB1737A54DD1Q24679424-40FB3445-6191-41CE-B1FA-57FFC5A43DA4Q26770053-A9208BA7-2F5E-4338-A775-293099706CF1Q27485880-18096CC9-AAA3-4AB2-BFAA-5833115DD3F7Q28115000-A8AC2741-288A-4FF6-B328-3E29690EB00CQ28205051-3BE6CB3B-45A6-4AA0-942B-60D5AA95ABAAQ28205748-59D74CCB-FD71-4D15-8B0A-94E7246A3442Q28208031-C70E3F69-4B0B-45E6-A558-598521FE3769Q28235003-B4ABA1E0-221C-45DF-94A8-A09F02BCA798Q28236961-CD75B231-DEF5-44CC-9F03-3103E5F20905Q28264728-F87723CA-FFAC-4260-AAB5-A04510C499F0Q28268615-163D7BAA-C713-4D5D-8178-4366F26C67ADQ28270038-10799625-5E61-411B-ABB4-B22639E50135Q28360379-FB69DD63-C7DB-41ED-9865-D97C487D6006Q28505156-91EE981E-7331-4D42-B3EB-026271059ED2Q28538306-C734686D-437B-47CB-AFC5-9639E03FB6EBQ28592530-14605B44-13D9-4FF9-ADA2-5F2729BF8158Q30164767-1C13B913-9C87-45B5-A5EF-3B9912938F0FQ30410553-02975B04-3784-4CFC-9873-DA98ACA47E61Q30411066-79732F10-DE46-479A-A92F-FB9909788EE2
P2860
Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase
description
2000 nî lūn-bûn
@nan
2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Human scribble (Vartul) is tar ...... E6AP ubiquitin-protein ligase
@ast
Human scribble (Vartul) is tar ...... E6AP ubiquitin-protein ligase
@en
Human scribble (Vartul) is tar ...... E6AP ubiquitin-protein ligase
@nl
type
label
Human scribble (Vartul) is tar ...... E6AP ubiquitin-protein ligase
@ast
Human scribble (Vartul) is tar ...... E6AP ubiquitin-protein ligase
@en
Human scribble (Vartul) is tar ...... E6AP ubiquitin-protein ligase
@nl
prefLabel
Human scribble (Vartul) is tar ...... E6AP ubiquitin-protein ligase
@ast
Human scribble (Vartul) is tar ...... E6AP ubiquitin-protein ligase
@en
Human scribble (Vartul) is tar ...... E6AP ubiquitin-protein ligase
@nl
P2860
P3181
P1476
Human scribble (Vartul) is tar ...... E6AP ubiquitin-protein ligase
@en
P2093
J M Huibregtse
S Nakagawa
P2860
P304
P3181
P356
10.1128/MCB.20.21.8244-8253.2000
P407
P577
2000-11-01T00:00:00Z