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T cell homeostatic proliferation elicits effective antitumor autoimmunity

T cell homeostatic proliferation elicits effective antitumor autoimmunity

http://www.wikidata.org/entity/Q24553060

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Focus on adoptive T cell transfer trials in melanoma Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells.Adoptive cell transfer: a clinical path to effective cancer immunotherapy Chimeric antigen receptor therapy for cancer T-cell receptor gene therapy--ready to go viral?Harnessing the Microbiome to Enhance Cancer Immunotherapy Learning and memory ... and the immune system.Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity In vivo imaging of T cell delivery to tumors after adoptive transfer therapy.Quantitative monitoring of mouse lung tumors by magnetic resonance imaging.Enhanced lymphocyte proliferation responses in pediatric patients early after myelosuppressive chemotherapy.Targeting macrophage anti-tumor activity to suppress melanoma progression.Heat shock protein vaccination and directed IL-2 therapy amplify tumor immunity rapidly following bone marrow transplantation in mice.History and current state of immunotherapy in glioma and brain metastasis.IL-2 mediates CD4+ T cell help in the breakdown of memory-like CD8+ T cell tolerance under lymphopenic conditions The allure and peril of hematopoietic stem cell transplantation: overcoming immune challenges to improve success.Homeostatic proliferation is a barrier to transplantation tolerance.In vivo cyclophosphamide and IL-2 treatment impedes self-antigen-induced effector CD4 cell tolerization: implications for adoptive immunotherapy.Combined IL-15/IL-15Ralpha immunotherapy maximizes IL-15 activity in vivo.Depletion of tumor-induced Treg prior to reconstitution rescues enhanced priming of tumor-specific, therapeutic effector T cells in lymphopenic hosts Peripheral Tolerization of Effector and Memory T Cells: Implications for Autoimmunity and Tumor-Immunity.Memory-like CD8+ T cells generated during homeostatic proliferation defer to antigen-experienced memory cells.Biology and clinical effects of natural killer cells in allogeneic transplantation.Differential mechanisms of memory CD8 T cell maintenance by individual myeloid cell types.Principles of adoptive T cell cancer therapy.Heterologous immunity between viruses Systemic autoimmunity and lymphoproliferation are associated with excess IL-7 and inhibited by IL-7Rα blockade.Type 1 interferons and antiviral CD8 T-cell responses.Control of homeostatic proliferation by regulatory T cells.Lymphodepletion is permissive to the development of spontaneous T-cell responses to the self-antigen PR1 early after allogeneic stem cell transplantation and in patients with acute myeloid leukemia undergoing WT1 peptide vaccination following chemot IL-18 synergizes with IL-7 to drive slow proliferation of naive CD8 T cells by costimulating self-peptide-mediated TCR signals.Living-related donor renal transplantation in HIV+ recipients using alemtuzumab preconditioning and steroid-free tacrolimus monotherapy: a single center preliminary experience.Sinks, suppressors and antigen presenters: how lymphodepletion enhances T cell-mediated tumor immunotherapy.Anti-leukemia effect of ex vivo expanded DNT cells from AML patients: a potential novel autologous T-cell adoptive immunotherapy.Myeloablative temozolomide enhances CD8⁺ T-cell responses to vaccine and is required for efficacy against brain tumors in mice.Greater chemotherapy-induced lymphopenia enhances tumor-specific immune responses that eliminate EGFRvIII-expressing tumor cells in patients with glioblastoma.Making room for T cells Therapeutic cancer vaccines: are we there yet?A central role for mTOR kinase in homeostatic proliferation induced CD8+ T cell memory and tumor immunity

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P2860

T cell homeostatic proliferation elicits effective antitumor autoimmunity

http://www.wikidata.org/entity/Q24553060

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2002 nî lūn-bûn

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2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2002 թվականի հուլիսին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

T cell homeostatic proliferation elicits effective antitumor autoimmunity

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T cell homeostatic proliferation elicits effective antitumor autoimmunity

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T cell homeostatic proliferation elicits effective antitumor autoimmunity

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type

label

T cell homeostatic proliferation elicits effective antitumor autoimmunity

@ast

T cell homeostatic proliferation elicits effective antitumor autoimmunity

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T cell homeostatic proliferation elicits effective antitumor autoimmunity

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prefLabel

T cell homeostatic proliferation elicits effective antitumor autoimmunity

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T cell homeostatic proliferation elicits effective antitumor autoimmunity

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T cell homeostatic proliferation elicits effective antitumor autoimmunity

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Journal of Clinical Investigation

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T cell homeostatic proliferation elicits effective antitumor autoimmunity

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P2093

Andreas G Niethammer

http://www.w3.org/2001/XMLSchema#string

Argyrios N Theofilopoulos

http://www.w3.org/2001/XMLSchema#string

Brian R Lawson

http://www.w3.org/2001/XMLSchema#string

Norbert Wagner

http://www.w3.org/2001/XMLSchema#string

Ralph A Reisfeld

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Roberto Baccala

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Wolfgang Dummer

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P2860

Isolation of GD3 synthase gene by expression cloning of GM3 alpha-2,8-sialyltransferase cDNA using anti-GD2 monoclonal antibody

Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin

Lymphotoxin-alpha-deficient mice. Effects on secondary lymphoid organ development and humoral immune responsiveness

Mechanisms of exogenous antigen presentation by MHC class I molecules in vitro and in vivo: implications for generating CD8+ T cell responses to infectious agents, tumors, transplants, and vaccines.

Selecting and maintaining a diverse T-cell repertoire.

Tumor lysate-pulsed dendritic cells can elicit an effective antitumor immune response during early lymphoid recovery.

Homeostatic T cell proliferation: how far can T cells be activated to self-ligands?

Dependence of lymphopenia-induced T cell proliferation on the abundance of peptide/ MHC epitopes and strength of their interaction with T cell receptors.

Immunity against cancer: lessons learned from melanoma.

Cross-presentation, dendritic cells, tolerance and immunity.

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185-92

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1804457

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10.1172/JCI0215175

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2

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11257085

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12122110

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