Disruption of mouse SNM1 causes increased sensitivity to the DNA interstrand cross-linking agent mitomycin C
about
Metallo-beta-lactamase fold within nucleic acids processing enzymes: the beta-CASP family.hSnm1 colocalizes and physically associates with 53BP1 before and after DNA damageA CPSF-73 homologue is required for cell cycle progression but not cell growth and interacts with a protein having features of CPSF-100DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formationDeficiency in SNM1 abolishes an early mitotic checkpoint induced by spindle stressArtemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint responseHomologous recombination in DNA repair and DNA damage toleranceThe hSNM1 protein is a DNA 5'-exonucleaseRole of human Pso4 in mammalian DNA repair and association with terminal deoxynucleotidyl transferaseThe role of ADP-ribosylation in regulating DNA interstrand crosslink repairXPF-ERCC1 acts in Unhooking DNA interstrand crosslinks in cooperation with FANCD2 and FANCP/SLX4Defective DNA repair and increased genomic instability in Artemis-deficient murine cellsApollo contributes to G overhang maintenance and protects leading-end telomeresSNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repairEndogenous hSNM1B/Apollo interacts with TRF2 and stimulates ATM in response to ionizing radiation.Identification of genes associated with multiple cancers via integrative analysis.Gene expression profiling of long-lived dwarf mice: longevity-associated genes and relationships with diet, gender and aging.A new nuclease member of the FAN club.The MRT-1 nuclease is required for DNA crosslink repair and telomerase activity in vivo in Caenorhabditis elegansDNA interstrand crosslink repair in mammalian cells: step by step.RAD18-dependent recruitment of SNM1A to DNA repair complexes by a ubiquitin-binding zinc finger.Sequence variants of elaC homolog 2 (Escherichia coli) (ELAC2) gene and susceptibility to prostate cancer in the Health Professionals Follow-Up StudyThe multifunctional SNM1 gene family: not just nucleasesSnm1-deficient mice exhibit accelerated tumorigenesis and susceptibility to infection.The telomeric protein SNM1B/Apollo is required for normal cell proliferation and embryonic development.Orchestrating the nucleases involved in DNA interstrand cross-link (ICL) repair.Expansion of the zinc metallo-hydrolase family of the beta-lactamase fold.RPA inhibition increases replication stress and suppresses tumor growth.Snm1B interacts with PSF2.hSnm1B is a novel telomere-associated protein.Nucleases of the metallo-beta-lactamase family and their role in DNA and RNA metabolism.A large-scale screen for mutagen-sensitive loci in Drosophila.Snm1B/Apollo functions in the Fanconi anemia pathway in response to DNA interstrand crosslinks.Schizosaccharomyces pombe checkpoint response to DNA interstrand cross-linksArtemis sheds new light on V(D)J recombination.DNA interstrand crosslinks: natural and drug-induced DNA adducts that induce unique cellular responses.Fan1 deficiency results in DNA interstrand cross-link repair defects, enhanced tissue karyomegaly, and organ dysfunction.Contributions of DNA interstrand cross-links to aging of cells and organisms.Evidence that the DNA endonuclease ARTEMIS also has intrinsic 5'-exonuclease activity.Human SNM1A and XPF-ERCC1 collaborate to initiate DNA interstrand cross-link repair.
P2860
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P2860
Disruption of mouse SNM1 causes increased sensitivity to the DNA interstrand cross-linking agent mitomycin C
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2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
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2000 թվականի հուլիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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Disruption of mouse SNM1 cause ...... ross-linking agent mitomycin C
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Disruption of mouse SNM1 cause ...... ross-linking agent mitomycin C
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Disruption of mouse SNM1 cause ...... ross-linking agent mitomycin C
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Disruption of mouse SNM1 cause ...... ross-linking agent mitomycin C
@ast
Disruption of mouse SNM1 cause ...... ross-linking agent mitomycin C
@en
Disruption of mouse SNM1 cause ...... ross-linking agent mitomycin C
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Disruption of mouse SNM1 cause ...... ross-linking agent mitomycin C
@ast
Disruption of mouse SNM1 cause ...... ross-linking agent mitomycin C
@en
Disruption of mouse SNM1 cause ...... ross-linking agent mitomycin C
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P2093
P2860
P3181
P1476
Disruption of mouse SNM1 cause ...... ross-linking agent mitomycin C
@en
P2093
H van Steeg
J H Hoeijmakers
M L Dronkert
P2860
P304
P3181
P356
10.1128/MCB.20.13.4553-4561.2000
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P577
2000-07-01T00:00:00Z