Leukemic HRX fusion proteins inhibit GADD34-induced apoptosis and associate with the GADD34 and hSNF5/INI1 proteins - Wikidata - wikimedia - TriplyDB

Leukemic HRX fusion proteins inhibit GADD34-induced apoptosis and associate with the GADD34 and hSNF5/INI1 proteins

Leukemic HRX fusion proteins inhibit GADD34-induced apoptosis and associate with the GADD34 and hSNF5/INI1 proteins

http://www.wikidata.org/entity/Q24554418

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In vitro nuclear interactome of the HIV-1 Tat protein Interaction between growth arrest-DNA damage protein 34 and Src kinase Lyn negatively regulates genotoxic apoptosis Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1.Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1 alpha to the endoplasmic reticulum and promotes dephosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 Association with endoplasmic reticulum promotes proteasomal degradation of GADD34 protein A masked NES in INI1/hSNF5 mediates hCRM1-dependent nuclear export: implications for tumorigenesis Cell cycle arrest and repression of cyclin D1 transcription by INI1/hSNF5.MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein Human BAG-1 proteins bind to the cellular stress response protein GADD34 and interfere with GADD34 functions Apoptotic response of malignant rhabdoid tumor cells Endoplasmic Reticulum Stress and Associated ROS Systematic Classification of Mixed-Lineage Leukemia Fusion Partners Predicts Additional Cancer Pathways Revisiting the biology of infant t(4;11)/MLL-AF4+ B-cell acute lymphoblastic leukemia Gadd34 functional domains involved in growth suppression and apoptosis Neurabins recruit protein phosphatase-1 and inhibitor-2 to the actin cytoskeleton The human SNF5/INI1 protein facilitates the function of the growth arrest and DNA damage-inducible protein (GADD34) and modulates GADD34-bound protein phosphatase-1 activity Epigallocatechin-3-gallate (EGCG) protects against chromate-induced toxicity in vitro CpG-binding protein is a nuclear matrix- and euchromatin-associated protein localized to nuclear speckles containing human trithorax. Identification of nuclear matrix targeting signals Inhibition of GADD34, the stress-inducible regulatory subunit of the endoplasmic reticulum stress response, does not enhance functional recovery after spinal cord injury Mediators of endoplasmic reticulum stress-induced apoptosis A microarray study of gene and protein regulation in human and rat brain following middle cerebral artery occlusion.Activation of Gadd34 by diverse apoptotic signals and suppression of its growth inhibitory effects by apoptotic inhibitors.Endothelin receptor B antagonists decrease glioma cell viability independently of their cognate receptor.The YEATS domain of Taf14 in Saccharomyces cerevisiae has a negative impact on cell growth.AlaArg motif in the carboxyl terminus of the gamma(1)34.5 protein of herpes simplex virus type 1 is required for the formation of a high-molecular-weight complex that dephosphorylates eIF-2alpha.mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK.MLL fusion partners AF4 and AF9 interact at subnuclear foci.The role of the MLL gene in infant leukemia.Melanoma differentiation associated gene-7/interleukin-24 potently induces apoptosis in human myeloid leukemia cells through a process regulated by endoplasmic reticulum stress.Common themes in the pathogenesis of acute myeloid leukemia.The Drosophila SNR1 (SNF5/INI1) subunit directs essential developmental functions of the Brahma chromatin remodeling complex MLL leukemia-associated rearrangements in peripheral blood lymphocytes from healthy individuals.Genetic and molecular analysis of region 88E9;88F2 in Drosophila melanogaster, including the ear gene related to human factors involved in lineage-specific leukemias.The integrase interactor 1 (INI1) proteins facilitate Tat-mediated human immunodeficiency virus type 1 transcription SWI/SNF chromatin remodelling complex and retroviral gene silencing.Chromosomal translocations involving the MLL gene: molecular mechanisms.Apoptosis and leukaemia.An eIF2α-binding motif in protein phosphatase 1 subunit GADD34 and its viral orthologs is required to promote dephosphorylation of eIF2α.Alteration of DNA damage signaling pathway profile in radiation-treated glioblastoma stem-like cells MLL: how complex does it get?

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Leukemic HRX fusion proteins inhibit GADD34-induced apoptosis and associate with the GADD34 and hSNF5/INI1 proteins

http://www.wikidata.org/entity/Q24554418

description

1999 nî lūn-bûn

@nan

1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

1999年の論文

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1999年論文

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1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

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name

Leukemic HRX fusion proteins i ...... GADD34 and hSNF5/INI1 proteins

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Leukemic HRX fusion proteins i ...... GADD34 and hSNF5/INI1 proteins

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Leukemic HRX fusion proteins i ...... GADD34 and hSNF5/INI1 proteins

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Leukemic HRX fusion proteins i ...... GADD34 and hSNF5/INI1 proteins

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Leukemic HRX fusion proteins i ...... GADD34 and hSNF5/INI1 proteins

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Leukemic HRX fusion proteins i ...... GADD34 and hSNF5/INI1 proteins

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Leukemic HRX fusion proteins i ...... GADD34 and hSNF5/INI1 proteins

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Leukemic HRX fusion proteins i ...... GADD34 and hSNF5/INI1 proteins

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Leukemic HRX fusion proteins i ...... GADD34 and hSNF5/INI1 proteins

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Molecular and Cellular Biology

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Leukemic HRX fusion proteins i ...... GADD34 and hSNF5/INI1 proteins

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A J Fornace

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D C Tkachuk

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D Y Wu

http://www.w3.org/2001/XMLSchema#string

H T Adler

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J M Payne

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R Chinery

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S J Kussick

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P2860

Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

Activation of extracellular signal-regulated kinase 2 by a novel Abl-binding protein, ST5

Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia

Purification and biochemical heterogeneity of the mammalian SWI-SNF complex

ENL, the gene fused with HRX in t(11;19) leukemias, encodes a nuclear protein with transcriptional activation potential in lymphoid and myeloid cells

An RNA polymerase II elongation factor encoded by the human ELL gene

Mammalian GADD34, an apoptosis- and DNA damage-inducible gene

Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias

EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia

The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth

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7050-60

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scholarly article

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10.1128/MCB.19.10.7050

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10

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19

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1999-10-01T00:00:00Z

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10490642

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apoptotic process

P932

84700

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