SCFSkp2 complex targeted by Epstein-Barr virus essential nuclear antigen - Wikidata - wikimedia - TriplyDB

SCFSkp2 complex targeted by Epstein-Barr virus essential nuclear antigen

SCFSkp2 complex targeted by Epstein-Barr virus essential nuclear antigen

http://www.wikidata.org/entity/Q24556627

about

Epstein-Barr virus nuclear antigen 3C interacts with and enhances the stability of the c-Myc oncoprotein Epstein-Barr virus latent antigen 3C can mediate the degradation of the retinoblastoma protein through an SCF cellular ubiquitin ligase The Modulation of Apoptotic Pathways by Gammaherpesviruses Role of EBNA-3 Family Proteins in EBV Associated B-cell Lymphomagenesis Induction of p16(INK4a) is the major barrier to proliferation when Epstein-Barr virus (EBV) transforms primary B cells into lymphoblastoid cell lines.Epigenetic repression of p16(INK4A) by latent Epstein-Barr virus requires the interaction of EBNA3A and EBNA3C with CtBP.Extensive co-operation between the Epstein-Barr virus EBNA3 proteins in the manipulation of host gene expression and epigenetic chromatin modification.Epstein-Barr virus nuclear antigen 3C facilitates G1-S transition by stabilizing and enhancing the function of cyclin D1.Upregulation of the cell-cycle regulator RGC-32 in Epstein-Barr virus-immortalized cells.Epstein-Barr virus nuclear antigen 3C stabilizes Gemin3 to block p53-mediated apoptosis.Epstein-Barr virus nuclear antigen 3A protein regulates CDKN2B transcription via interaction with MIZ-1 E2F1 mediated apoptosis induced by the DNA damage response is blocked by EBV nuclear antigen 3C in lymphoblastoid cells.Epstein-Barr virus nuclear antigens 3C and 3A maintain lymphoblastoid cell growth by repressing p16INK4A and p14ARF expression.The EBV Latent Antigen 3C Inhibits Apoptosis through Targeted Regulation of Interferon Regulatory Factors 4 and 8.EBNA3C attenuates the function of p53 through interaction with inhibitor of growth family proteins 4 and 5 Epstein-Barr virus nuclear antigen 3C targets p53 and modulates its transcriptional and apoptotic activities.EBNA3C augments Pim-1 mediated phosphorylation and degradation of p21 to promote B-cell proliferation Epstein-Barr virus nuclear protein EBNA3C is required for cell cycle progression and growth maintenance of lymphoblastoid cells.Kaposi's sarcoma herpesvirus-encoded latency-associated nuclear antigen stabilizes intracellular activated Notch by targeting the Sel10 protein.Viral modulators of cullin RING ubiquitin ligases: culling the host defense.EBV-encoded EBNA-6 binds and targets MRS18-2 to the nucleus, resulting in the disruption of pRb-E2F1 complexes The Role of F-Box Proteins during Viral Infection.Regulation of the retinoblastoma proteins by the human herpesviruses.Epstein-Barr virus nuclear protein EBNA3C residues critical for maintaining lymphoblastoid cell growth.Nucleoside diphosphate kinase/Nm23 and Epstein-Barr virus.Epstein-Barr virus-associated B-cell lymphomas: pathogenesis and clinical outcomes.Viral takeover of the host ubiquitin system.Impact of EBV essential nuclear protein EBNA-3C on B-cell proliferation and apoptosis.Deregulation of the cell cycle machinery by Epstein-Barr virus nuclear antigen 3C.Epstein-Barr virus latency: current and future perspectives.Epstein-Barr virus essential antigen EBNA3C attenuates H2AX expression.Transcriptional downregulation of p27KIP1 through regulation of E2F function during LMP1-mediated transformation.Epstein-Barr virus nuclear antigen 3C augments Mdm2-mediated p53 ubiquitination and degradation by deubiquitinating Mdm2.EBNA3C-mediated regulation of aurora kinase B contributes to Epstein-Barr virus-induced B-cell proliferation through modulation of the activities of the retinoblastoma protein and apoptotic caspases Phosphorylation of p27Kip1 by Epstein-Barr virus protein kinase induces its degradation through SCFSkp2 ubiquitin ligase actions during viral lytic replication.Therapeutic Strategies against Epstein-Barr Virus-Associated Cancers Using Proteasome Inhibitors.The Cooperative Functions of the EBNA3 Proteins Are Central to EBV Persistence and Latency.Transcriptional and epigenetic modulation of autophagy promotes EBV oncoprotein EBNA3C induced B-cell survival.

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SCFSkp2 complex targeted by Epstein-Barr virus essential nuclear antigen

http://www.wikidata.org/entity/Q24556627

description

2005 nî lūn-bûn

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2005 թուականի Մարտին հրատարակուած գիտական յօդուած

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2005 թվականի մարտին հրատարակված գիտական հոդված

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

@zh-my

2005年学术文章

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2005年學術文章

@yue

name

SCFSkp2 complex targeted by Epstein-Barr virus essential nuclear antigen

@ast

SCFSkp2 complex targeted by Epstein-Barr virus essential nuclear antigen

@en

SCFSkp2 complex targeted by Epstein-Barr virus essential nuclear antigen

@nl

type

label

SCFSkp2 complex targeted by Epstein-Barr virus essential nuclear antigen

@ast

SCFSkp2 complex targeted by Epstein-Barr virus essential nuclear antigen

@en

SCFSkp2 complex targeted by Epstein-Barr virus essential nuclear antigen

@nl

prefLabel

SCFSkp2 complex targeted by Epstein-Barr virus essential nuclear antigen

@ast

SCFSkp2 complex targeted by Epstein-Barr virus essential nuclear antigen

@en

SCFSkp2 complex targeted by Epstein-Barr virus essential nuclear antigen

@nl

P1433

Q24556627-AC9A1738-0425-4E99-8131-7B807D78C9CF

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Q24556627-B518D65C-58B2-4505-9A85-B95E6E980B6A

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Q24556627-79CB582B-B354-4C5A-BF4B-05C00E816D57

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Q24556627-9A6F2C7F-5E66-4821-A209-CA1F16DDA754

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P356

MCB.25.5.1749-1763.2005

P1433

Molecular and Cellular Biology

P1476

SCFSkp2 complex targeted by Epstein-Barr virus essential nuclear antigen

@en

P2093

Jason S Knight

http://www.w3.org/2001/XMLSchema#string

Nikhil Sharma

http://www.w3.org/2001/XMLSchema#string

P2860

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase

Epstein-Barr virus nuclear antigen 3C and prothymosin alpha interact with the p300 transcriptional coactivator at the CH1 and CH3/HAT domains and cooperate in regulation of transcription and histone acetylation.

Role of the F-box protein Skp2 in lymphomagenesis

SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

Modulation of histone acetyltransferase activity through interaction of epstein-barr nuclear antigen 3C with prothymosin alpha

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation

P304

1749-63

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scholarly article

P3181

2038202

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P356

10.1128/MCB.25.5.1749-1763.2005

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P407

P433

5

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25

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Erle S Robertson

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2005-03-01T00:00:00Z

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P698

15713632

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P921

Epstein–Barr virus

P932

549383

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