The trans-Golgi network-associated human ubiquitin-protein ligase POSH is essential for HIV type 1 production
about
Trafficking of HIV-1 RNA is mediated by heterogeneous nuclear ribonucleoprotein A2 expression and impacts on viral assemblyRequirement for microtubule integrity in the SOCS1-mediated intracellular dynamics of HIV-1 GagDeficiency of niemann-pick type C-1 protein impairs release of human immunodeficiency virus type 1 and results in Gag accumulation in late endosomal/lysosomal compartmentsRegulation of STIM1 and SOCE by the ubiquitin-proteasome system (UPS)Modulation of D-serine levels via ubiquitin-dependent proteasomal degradation of serine racemasePOSH stimulates the ubiquitination and the clathrin-independent endocytosis of ROMK1 channels.Exploring the functional interaction between POSH and ALIX and the relevance to HIV-1 release.Human Ubc9 contributes to production of fully infectious human immunodeficiency virus type 1 virionsPatented small molecule inhibitors in the ubiquitin proteasome systemMurine leukemia virus spreading in mice impaired in the biogenesis of secretory lysosomes and Ca2+-regulated exocytosis.Anx2 interacts with HIV-1 Gag at phosphatidylinositol (4,5) bisphosphate-containing lipid rafts and increases viral production in 293T cellsDefects in cellular sorting and retroviral assembly induced by GGA overexpressionFilamin A protein interacts with human immunodeficiency virus type 1 Gag protein and contributes to productive particle assembly.HIV-1 Vpr redirects host ubiquitination pathway.Human Ubc9 is involved in intracellular HIV-1 Env stability after trafficking out of the trans-Golgi network in a Gag dependent manner.Macrophages and Cell-Cell Spread of HIV-1.Evidence of a role for soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) machinery in HIV-1 assembly and release.The clathrin adaptor complex AP-1 binds HIV-1 and MLV Gag and facilitates their budding.HIV Assembly and Budding: Ca(2+) Signaling and Non-ESCRT Proteins Set the Stage.The ubiquitin-proteasome system in HIV replication: potential targets for antiretroviral therapy.The ubiquitin E3 ligase POSH regulates calcium homeostasis through spatial control of Herp.New insights into HIV assembly and trafficking.SOCS1 is an inducible host factor during HIV-1 infection and regulates the intracellular trafficking and stability of HIV-1 Gag.The role of ubiquitin in retroviral egress.The scaffold protein POSH regulates axon outgrowth.HIV-1 Assembly at the Plasma Membrane: Gag Trafficking and Localization.Roles of the interactions between Env and Gag proteins in the HIV-1 replication cycle.Intracellular transport of human immunodeficiency virus type 1 genomic RNA and viral production are dependent on dynein motor function and late endosome positioningDynamic interactions of proteins in complex networks: identifying the complete set of interacting E2s for functional investigation of E3-dependent protein ubiquitination.HIV-1, ubiquitin and ubiquitin-like proteins: the dialectic interactions of a virus with a sophisticated network of post-translational modifications.Activation of the retroviral budding factor ALIX.Inhibitors of Deubiquitinating Enzymes Block HIV-1 Replication and Augment the Presentation of Gag-Derived MHC-I Epitopes.Protein interaction screening identifies SH3RF1 as a new regulator of FAT1 protein levels.Major histocompatibility complex class II molecules promote human immunodeficiency virus type 1 assembly and budding to late endosomal/multivesicular body compartments.The host protein Staufen1 participates in human immunodeficiency virus type 1 assembly in live cells by influencing pr55Gag multimerization.A Truncated Nef Peptide from SIVcpz Inhibits the Production of HIV-1 Infectious Progeny.The Src kinase Lck facilitates assembly of HIV-1 at the plasma membrane.Functions of early (AP-2) and late (AIP1/ALIX) endocytic proteins in equine infectious anemia virus budding.POSH, a scaffold protein for JNK signaling, binds to ALG-2 and ALIX in Drosophila.POSH promotes cell survival in Drosophila and in human RASF cells.
P2860
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P2860
The trans-Golgi network-associated human ubiquitin-protein ligase POSH is essential for HIV type 1 production
description
2005 nî lūn-bûn
@nan
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2005年の論文
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年學術文章
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name
The trans-Golgi network-associ ...... tial for HIV type 1 production
@ast
The trans-Golgi network-associ ...... tial for HIV type 1 production
@en
The trans-Golgi network-associ ...... tial for HIV type 1 production
@nl
type
label
The trans-Golgi network-associ ...... tial for HIV type 1 production
@ast
The trans-Golgi network-associ ...... tial for HIV type 1 production
@en
The trans-Golgi network-associ ...... tial for HIV type 1 production
@nl
prefLabel
The trans-Golgi network-associ ...... tial for HIV type 1 production
@ast
The trans-Golgi network-associ ...... tial for HIV type 1 production
@en
The trans-Golgi network-associ ...... tial for HIV type 1 production
@nl
P2093
P2860
P3181
P356
P1476
The trans-Golgi network-associ ...... tial for HIV type 1 production
@en
P2093
Alin Sela-Brown
Dalit Konforty
Daniel Taglicht
Danny Ben-Avraham
Daphna Gordon
Elanite Caspi-Bachar
Haim M Barr
Haim Moskowitz
Iris Alchanati
P2860
P304
P3181
P356
10.1073/PNAS.0408717102
P407
P577
2005-02-01T00:00:00Z