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Structural basis for peptidoglycan binding by peptidoglycan recognition proteins

Structural basis for peptidoglycan binding by peptidoglycan recognition proteins

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Genetic Association of Peptidoglycan Recognition Protein Variants with Inflammatory Bowel Disease Structural insights into the bactericidal mechanism of human peptidoglycan recognition proteins Dual strategies for peptidoglycan discrimination by peptidoglycan recognition proteins (PGRPs).Crystal structure of human peptidoglycan recognition protein I alpha bound to a muramyl pentapeptide from Gram-positive bacteria Bacterial peptidoglycan degrading enzymes and their impact on host muropeptide detection Human peptidoglycan recognition protein S is an effector of neutrophil-mediated innate immunity Elucidation of the molecular recognition of bacterial cell wall by modular pneumococcal phage endolysin CPL-1 Crystal Structures of Bacterial Peptidoglycan Amidase AmpD and an Unprecedented Activation Mechanism Structural basis of heparin binding to camel peptidoglycan recognition protein-S Structural and Functional Insights into Peptidoglycan Access for the Lytic Amidase LytA of Streptococcus pneumoniae Peptidoglycan recognition proteins kill bacteria by inducing oxidative, thiol, and metal stress Ligand specificities and structural requirements of two Tachypleus plasma lectins for bacterial trapping Peptidoglycan recognition proteins are a new class of human bactericidal proteins.Anopheles gambiae PGRPLC-mediated defense against bacteria modulates infections with malaria parasites.Ligand-induced dimerization of Drosophila peptidoglycan recognition proteins in vitro.Structure of the ectodomain of Drosophila peptidoglycan-recognition protein LCa suggests a molecular mechanism for pattern recognition.The extracytoplasmic domain of the Mycobacterium tuberculosis Ser/Thr kinase PknB binds specific muropeptides and is required for PknB localization Host-guest chemistry of the peptidoglycan Involvement of Manduca sexta peptidoglycan recognition protein-1 in the recognition of bacteria and activation of prophenoloxidase system.Gene silencing and overexpression of porcine peptidoglycan recognition protein long isoforms: involvement in beta-defensin-1 expression Peptidoglycan recognition proteins: modulators of the microbiome and inflammation.The peptidoglycan recognition protein PGRP-SC1a is essential for Toll signaling and phagocytosis of Staphylococcus aureus in Drosophila.Mouse peptidoglycan recognition protein PGLYRP-1 plays a role in the host innate immune response against Listeria monocytogenes infection.Transcriptome analysis of the white body of the squid Euprymna tasmanica with emphasis on immune and hematopoietic gene discovery.Modification of the structure of peptidoglycan is a strategy to avoid detection by nucleotide-binding oligomerization domain protein 1.Clustering of peptidoglycan recognition protein-SA is required for sensing lysine-type peptidoglycan in insects.Activity Augmentation of Amphioxus Peptidoglycan Recognition Protein BbtPGRP3 via Fusion with a Chitin Binding Domain Structural studies on molecular interactions between camel peptidoglycan recognition protein, CPGRP-S, and peptidoglycan moieties N-acetylglucosamine and N-acetylmuramic acid.Mammalian PGRPs: novel antibacterial proteins.The peptidoglycan recognition proteins (PGRPs).Molecular basis and phenotype of methicillin resistance in Staphylococcus aureus and insights into new beta-lactams that meet the challenge.Characterization of expression, activity and role in antibacterial immunity of Anopheles gambiae lysozyme c-1.Review: Mammalian peptidoglycan recognition proteins (PGRPs) in innate immunity.The bactericidal activity of the C-type lectin RegIIIβ against Gram-negative bacteria involves binding to lipid A.Molecular cloning and characterization of a short peptidoglycan recognition protein from silkworm Bombyx mori.Non-canonical roles of tRNAs and tRNA mimics in bacterial cell biology Orthologous and Paralogous AmpD Peptidoglycan Amidases from Gram-Negative Bacteria.Peptidoglycan recognition protein-peptidoglycan complexes increase monocyte/macrophage activation and enhance the inflammatory response.Binding and Cellular Activation Studies Reveal That Toll-like Receptor 2 Can Differentially Recognize Peptidoglycan from Gram-positive and Gram-negative Bacteria.Synthesis and proinflammatory properties of muramyl tripeptides containing lysine and diaminopimelic acid moieties.

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Structural basis for peptidoglycan binding by peptidoglycan recognition proteins

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Structural basis for peptidoglycan binding by peptidoglycan recognition proteins

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Structural basis for peptidoglycan binding by peptidoglycan recognition proteins

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Structural basis for peptidoglycan binding by peptidoglycan recognition proteins

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Structural basis for peptidoglycan binding by peptidoglycan recognition proteins

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Structural basis for peptidoglycan binding by peptidoglycan recognition proteins

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Structural basis for peptidoglycan binding by peptidoglycan recognition proteins

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Structural basis for peptidoglycan binding by peptidoglycan recognition proteins

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Structural basis for peptidoglycan binding by peptidoglycan recognition proteins

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Structural basis for peptidoglycan binding by peptidoglycan recognition proteins

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Structural basis for peptidoglycan binding by peptidoglycan recognition proteins

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Abhijit Roychowdhury

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Brian Ember

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Rongjin Guan

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Roy A Mariuzza

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Sanjay Kumar

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P2860

Peptidoglycan recognition proteins: a novel family of four human innate immunity pattern recognition molecules

CD14 is a cell-activating receptor for bacterial peptidoglycan

A peptidoglycan recognition protein in innate immunity conserved from insects to humans

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Crystal structure of peptidoglycan recognition protein LB from Drosophila melanogaster

The structure of bacteriophage T7 lysozyme, a zinc amidase and an inhibitor of T7 RNA polymerase

The finer things in X-ray diffraction data collection

XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density

Human peptidoglycan recognition protein-L is an N-acetylmuramoyl-L-alanine amidase

Formation of the glycan chains in the synthesis of bacterial peptidoglycan

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