FMS mutations in myelodysplastic, leukemic, and normal subjects
about
A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemiaThe role of the ubiquitination-proteasome pathway in breast cancer: ubiquitin mediated degradation of growth factor receptors in the pathogenesis and treatment of cancerAssociation of the T allele of an intronic single nucleotide polymorphism in the colony stimulating factor 1 receptor with Crohn's disease: a case-control studyEngineering mouse models with myelodysplastic syndrome human candidate genes; how relevant are they?IDH1 mutations in patients with myelodysplastic syndromes are associated with an unfavorable prognosis.RNA-seq identifies clinically relevant fusion genes in leukemia including a novel MEF2D/CSF1R fusion responsive to imatinib.Activating point mutations in the common beta subunit of the human GM-CSF, IL-3 and IL-5 receptors suggest the involvement of beta subunit dimerization and cell type-specific molecules in signallingAML1 interconnected pathways of leukemogenesisc-Cbl associates directly with the C-terminal tail of the receptor for the macrophage colony-stimulating factor, c-Fms, and down-modulates this receptor but not the viral oncogene v-FmsThe Src-like adaptor protein 2 regulates colony-stimulating factor-1 receptor signaling and down-regulation.Random mutagenesis of CSF-1 receptor (FMS) reveals multiple sites for activating mutations within the extracellular domainAn excellent monitoring system for surface ubiquitination-induced internalization in mammalsEpstein-Barr virus associated B-cell lymphoma of brain developing in myelodysplastic syndrome with c-kit mutation (Try-557 -->stop).Cbl-mediated K63-linked ubiquitination of JAK2 enhances JAK2 phosphorylation and signal transduction.Cbl and human myeloid neoplasms: the Cbl oncogene comes of age.Blocking autocrine VEGF signaling by sunitinib, an anti-cancer drug, promotes embryonic stem cell self-renewal and somatic cell reprogramming.Class III receptor tyrosine kinases: role in leukaemogenesis.The process of leukemogenesisReceptor tyrosine kinase mutations in myeloid neoplasms.Gastrointestinal pacemaker cell tumor (GIPACT): gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal.Analysis of Somatic Mutations in Cancer: Molecular Mechanisms of Activation in the ErbB Family of Receptor Tyrosine Kinases.Configuration of the TP53 gene as an independent prognostic parameter of myelodysplastic syndrome.The MAPK ERK5, but not ERK1/2, inhibits the progression of monocytic phenotype to the functioning macrophage.FLT3: ITDoes matter in leukemia.A point mutation in the extracellular domain of KIT promotes tumorigenesis of mast cells via ligand-independent auto-dimerizationMutations in the colony stimulating factor 1 receptor (CSF1R) gene cause hereditary diffuse leukoencephalopathy with spheroids.Molecular therapeutic approaches to acute myeloid leukemia: targeting aberrant chromatin dynamics and signal transduction.Study of p53 in elderly patients with myelodysplastic syndromes by immunohistochemistry and DNA analysisThe use of next-generation sequencing in movement disordersPharmacogenetics of alkylator-associated acute myeloid leukemia.Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia.CSF-1R up-regulation is associated with response to pharmacotherapy targeting tyrosine kinase activity in AML cell lines.CSF1R mosaicism in a family with hereditary diffuse leukoencephalopathy with spheroidsRoles for deregulated receptor tyrosine kinases and their downstream signaling molecules in hematologic malignancies.Molecular and chromosomal alterations: new therapies for relapsed acute myeloid leukemia.Degradation of activated protein kinases by ubiquitination.The chimeric genes AML1/MDS1 and AML1/EAP inhibit AML1B activation at the CSF1R promoter, but only AML1/MDS1 has tumor-promoter properties.Prognostic molecular markers in myelodysplastic syndromes.Receptor tyrosine kinases: from biology to pathology.Molecular and genetic features of myelodysplastic syndromes.
P2860
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P2860
FMS mutations in myelodysplastic, leukemic, and normal subjects
description
1990 nî lūn-bûn
@nan
1990 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
FMS mutations in myelodysplastic, leukemic, and normal subjects
@ast
FMS mutations in myelodysplastic, leukemic, and normal subjects
@en
FMS mutations in myelodysplastic, leukemic, and normal subjects
@nl
type
label
FMS mutations in myelodysplastic, leukemic, and normal subjects
@ast
FMS mutations in myelodysplastic, leukemic, and normal subjects
@en
FMS mutations in myelodysplastic, leukemic, and normal subjects
@nl
prefLabel
FMS mutations in myelodysplastic, leukemic, and normal subjects
@ast
FMS mutations in myelodysplastic, leukemic, and normal subjects
@en
FMS mutations in myelodysplastic, leukemic, and normal subjects
@nl
P2093
P2860
P356
P1476
FMS mutations in myelodysplastic, leukemic, and normal subjects
@en
P2093
P2860
P304
P356
10.1073/PNAS.87.4.1377
P407
P577
1990-02-01T00:00:00Z