Mutations of human myristoyl-CoA:protein N-myristoyltransferase cause temperature-sensitive myristic acid auxotrophy in Saccharomyces cerevisiae
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Biochemical characterization of bovine brain myristoyl-CoA:protein N-myristoyltransferase type 2Human N-myristoyltransferase amino-terminal domain involved in targeting the enzyme to the ribosomal subcellular fraction2-Bromopalmitate and 2-(2-hydroxy-5-nitro-benzylidene)-benzo[b]thiophen-3-one inhibit DHHC-mediated palmitoylation in vitroN-terminal modifications of cellular proteins: The enzymes involved, their substrate specificities and biological effectsCrystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors reveal the functional roles of the N-terminal regionBiochemical studies of Saccharomyces cerevisiae myristoyl-coenzyme A:protein N-myristoyltransferase mutants.All about that fat: Lipid modification of proteins in Cryptococcus neoformansMolecular cloning, genomic organization, and biochemical characterization of myristoyl-CoA:protein N-myristoyltransferase from Arabidopsis thalianaGenetic and biochemical studies establish that the fungicidal effect of a fully depeptidized inhibitor of Cryptococcus neoformans myristoyl-CoA:protein N-myristoyltransferase (Nmt) is Nmt-dependent.N-myristoylation regulates the SnRK1 pathway in Arabidopsis.Single vector system for efficient N-myristoylation of recombinant proteins in E. coli.Aspergillus nidulans swoF encodes an N-myristoyl transferase.The complex and important cellular and metabolic functions of saturated fatty acidsAn improved method and cost effective strategy for soluble expression and purification of human N-myristoyltransferase 1 in E. coli.N-terminal region of the catalytic domain of human N-myristoyltransferase 1 acts as an inhibitory module.Targeted gene replacement demonstrates that myristoyl-CoA: protein N-myristoyltransferase is essential for viability of Cryptococcus neoformans.Use of photoactivatable peptide substrates of Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase (Nmt1p) to characterize a myristoyl-CoA-Nmt1p-peptide ternary complex and to provide evidence for an ordered reaction mechanismDual fatty acylation of p59(Fyn) is required for association with the T cell receptor zeta chain through phosphotyrosine-Src homology domain-2 interactions.Analogs of palmitoyl-CoA that are substrates for myristoyl-CoA:protein N-myristoyltransferaseN-myristoyltransferase in the leukocytic development processes.Efficient generation of infectious recombinant baculoviruses by site-specific transposon-mediated insertion of foreign genes into a baculovirus genome propagated in Escherichia coli.Down-regulation of N-myristoyl transferase expression in human T-cell line CEM by human immunodeficiency virus type-1 infection.The myristoylated amino terminus of ADP-ribosylation factor 1 is a phospholipid- and GTP-sensitive switch.Selective peptidic and peptidomimetic inhibitors of Candida albicans myristoylCoA: protein N-myristoyltransferase: a new approach to antifungal therapy.Characterization of N-myristoyltransferase from Plasmodium falciparum.In rat hepatocytes, myristic acid occurs through lipogenesis, palmitic acid shortening and lauric acid elongation.Purification and partial sequencing of myristoyl-CoA:protein N-myristoyltransferase from bovine brainCharacterization of human and rat brain myristoyl-CoA:protein N-myristoyltransferase: evidence for an alternative splice variant of the enzyme.Molecules incorporating a benzothiazole core scaffold inhibit the N-myristoyltransferase of Plasmodium falciparum.Amino acid residue penultimate to the amino-terminal gly residue strongly affects two cotranslational protein modifications, N-myristoylation and N-acetylation.Golgi traffic and integrity depend on N-myristoyl transferase-1 in Arabidopsis.C-terminal 15 kDa fragment of cytoskeletal actin is posttranslationally N-myristoylated upon caspase-mediated cleavage and targeted to mitochondria.High-throughput profiling of N-myristoylation substrate specificity across species including pathogens.Unexpected protein families including cell defense components feature in the N-myristoylome of a higher eukaryote.New nucleotide sequence data on the EMBL File Server
P2860
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P2860
Mutations of human myristoyl-CoA:protein N-myristoyltransferase cause temperature-sensitive myristic acid auxotrophy in Saccharomyces cerevisiae
description
1992 nî lūn-bûn
@nan
1992 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Mutations of human myristoyl-C ...... hy in Saccharomyces cerevisiae
@ast
Mutations of human myristoyl-C ...... hy in Saccharomyces cerevisiae
@en
Mutations of human myristoyl-C ...... hy in Saccharomyces cerevisiae
@nl
type
label
Mutations of human myristoyl-C ...... hy in Saccharomyces cerevisiae
@ast
Mutations of human myristoyl-C ...... hy in Saccharomyces cerevisiae
@en
Mutations of human myristoyl-C ...... hy in Saccharomyces cerevisiae
@nl
prefLabel
Mutations of human myristoyl-C ...... hy in Saccharomyces cerevisiae
@ast
Mutations of human myristoyl-C ...... hy in Saccharomyces cerevisiae
@en
Mutations of human myristoyl-C ...... hy in Saccharomyces cerevisiae
@nl
P2860
P356
P1476
Mutations of human myristoyl-C ...... hy in Saccharomyces cerevisiae
@en
P2093
P2860
P304
P356
10.1073/PNAS.89.9.4129
P407
P577
1992-05-01T00:00:00Z