Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA - Wikidata - wikimedia - TriplyDB

Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA

Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA

http://www.wikidata.org/entity/Q24562760

about

The adeno-associated virus type 2 regulatory proteins rep78 and rep68 interact with the transcriptional coactivator PC4.In vitro packaging of adeno-associated virus DNA Novel cis-acting replication element in the adeno-associated virus type 2 genome is involved in amplification of integrated rep-cap sequences.Efficient integration of recombinant adeno-associated virus DNA vectors requires a p5-rep sequence in cis.Adeno-associated virus Rep proteins target DNA sequences to a unique locus in the human genome Adeno-associated Virus as a Mammalian DNA Vector Adeno-associated virus: from defective virus to effective vector The effect of DNA-dependent protein kinase on adeno-associated virus replication Roles of adeno-associated virus Rep protein and human chromosome 19 in site-specific recombination Site-specific integration of adeno-associated virus involves partial duplication of the target locus.The Rep protein of adeno-associated virus type 2 interacts with single-stranded DNA-binding proteins that enhance viral replication.Adeno-associated virus site-specifically integrates into a muscle-specific DNA region Cellular proteins required for adeno-associated virus DNA replication in the absence of adenovirus coinfection.Genetic fate of recombinant adeno-associated virus vector genomes in muscle The Adeno-Associated Virus Genome Packaging Puzzle.DNA structure modulates the oligomerization properties of the AAV initiator protein Rep68.Human parvovirus B19 in rheumatoid arthritis.Integration preferences of wildtype AAV-2 for consensus rep-binding sites at numerous loci in the human genome.Human adeno-associated virus type 5 is only distantly related to other known primate helper-dependent parvoviruses.Cloning and characterization of adeno-associated virus type 5.Biochemical characterization of adeno-associated virus rep68 DNA helicase and ATPase activities.The Gordon Wilson Lecture. From basic virology to human gene therapy.Adeno-associated virus (AAV) type 5 Rep protein cleaves a unique terminal resolution site compared with other AAV serotypes.Analysis of the effects of charge cluster mutations in adeno-associated virus Rep68 protein in vitro Development of animal models for adeno-associated virus site-specific integration.Adeno-associated virus vectors and hematology Adeno-associated viral vectors for gene transfer and gene therapy.Stable secondary structure near the nicking site for adeno-associated virus type 2 Rep proteins on human chromosome 19 Inhibition of PrKX, a novel protein kinase, and the cyclic AMP-dependent protein kinase PKA by the regulatory proteins of adeno-associated virus type 2.The Rep52 gene product of adeno-associated virus is a DNA helicase with 3'-to-5' polarity.Adeno-associated virus vector-mediated transgene integration into neurons and other nondividing cell targets.Conditional site-specific integration into human chromosome 19 by using a ligand-dependent chimeric adeno-associated virus/Rep protein.A chimeric protein containing the N terminus of the adeno-associated virus Rep protein recognizes its target site in an in vivo assay.Adeno-associated virus major Rep78 protein disrupts binding of TATA-binding protein to the p97 promoter of human papillomavirus type 16 Mutational analysis of adeno-associated virus type 2 Rep68 protein endonuclease activity on partially single-stranded substrates.An adeno-associated virus (AAV) initiator protein, Rep78, catalyzes the cleavage and ligation of single-stranded AAV ori DNA.Mechanism of Rep-mediated adeno-associated virus origin nicking.Isolation of recombinant adeno-associated virus vector-cellular DNA junctions from mouse liver.Factors affecting the terminal resolution site endonuclease, helicase, and ATPase activities of adeno-associated virus type 2 Rep proteins Rep-mediated nicking of the adeno-associated virus origin requires two biochemical activities, DNA helicase activity and transesterification.

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Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA

http://www.wikidata.org/entity/Q24562760

description

1994 nî lūn-bûn

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1994 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

1994 թվականի հունիսին հրատարակված գիտական հոդված

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1994年の論文

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1994年論文

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1994年論文

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1994年論文

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1994年論文

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1994年論文

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name

Adeno-associated virus (AAV) R ...... integration site in human DNA

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Adeno-associated virus (AAV) R ...... integration site in human DNA

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Adeno-associated virus (AAV) R ...... integration site in human DNA

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Adeno-associated virus (AAV) R ...... integration site in human DNA

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Adeno-associated virus (AAV) R ...... integration site in human DNA

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Adeno-associated virus (AAV) R ...... integration site in human DNA

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Adeno-associated virus (AAV) R ...... integration site in human DNA

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Adeno-associated virus (AAV) R ...... integration site in human DNA

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PNAS.91.13.5808

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Proceedings of the National Academy of Sciences of the United States of America

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Adeno-associated virus (AAV) R ...... integration site in human DNA

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M D Weitzman

http://www.w3.org/2001/XMLSchema#string

R A Owens

http://www.w3.org/2001/XMLSchema#string

R M Kotin

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S R Kyöstiö

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P2860

Site-specific integration by adeno-associated virus

Latent infection of KB cells with adeno-associated virus type 2

Characterization of a preferred site on human chromosome 19q for integration of adeno-associated virus DNA by non-homologous recombination.

The AAV origin binding protein Rep68 is an ATP-dependent site-specific endonuclease with DNA helicase activity.

Targeted integration of adeno-associated virus (AAV) into human chromosome 19.

Sequence requirements of Escherichia coli attTn7, a specific site of transposon Tn7 insertion.

Biologically active Rep proteins of adeno-associated virus type 2 produced as fusion proteins in Escherichia coli

Identification of a DNA-binding domain in the amino terminus of adeno-associated virus Rep proteins

Features of the adeno-associated virus origin involved in substrate recognition by the viral Rep protein.

Repair of deletions and double-strand gaps by homologous recombination in a mammalian in vitro system.

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5808-12

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scholarly article

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1716660

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10.1073/PNAS.91.13.5808

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13

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91

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1994-06-21T00:00:00Z

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15183315

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8016070

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44086

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