Cerebellar ataxia and Purkinje cell dysfunction caused by Ca2+-activated K+ channel deficiency
about
The sodium-potassium pump controls the intrinsic firing of the cerebellar Purkinje neuronSimulation of alcohol action upon a detailed Purkinje neuron model and a simpler surrogate model that runs >400 times fasterRare structural variation of synapse and neurotransmission genes in autismWhat is the functional role of the thalidomide binding protein cereblon?Posttranscriptional regulation of BK channel splice variant stability by miR-9 underlies neuroadaptation to alcoholThe ducky(2J) mutation in Cacna2d2 results in reduced spontaneous Purkinje cell activity and altered gene expressionThe role of neuronal complexes in human X-linked brain diseasesBK channels: multiple sensors, one activation gateIntegration of modeling with experimental and clinical findings synthesizes and refines the central role of inositol 1,4,5-trisphosphate receptor 1 in spinocerebellar ataxiaHypoxia and ischemia-reperfusion: a BiK contribution?Mice with deficient BK channel function show impaired prepulse inhibition and spatial learning, but normal working and spatial reference memory.The sodium-activated potassium channel Slack is required for optimal cognitive flexibility in miceSplicing of the rSlo gene affects the molecular composition and drug response of Ca2+-activated K+ channels in skeletal muscleUrodynamic properties and neurotransmitter dependence of urinary bladder contractility in the BK channel deletion model of overactive bladderBK calcium-activated potassium channels regulate circadian behavioral rhythms and pacemaker outputDifferential trafficking of carboxyl isoforms of Ca2+-gated (Slo1) potassium channelsJunctophilin-mediated channel crosstalk essential for cerebellar synaptic plasticity.IRAG is essential for relaxation of receptor-triggered smooth muscle contraction by cGMP kinaseSK2 channel expression and function in cerebellar Purkinje cellsThe role of BKCa channels in electrical signal encoding in the mammalian auditory periphery.Deletion of the Ca2+-activated potassium (BK) alpha-subunit but not the BKbeta1-subunit leads to progressive hearing lossBK Channels in the Central Nervous System.Manipulation of BK channel expression is sufficient to alter auditory hair cell thresholds in larval zebrafish.Replication study of genome-wide associated SNPs with late-onset Alzheimer's diseaseOlivocochlear suppression of outer hair cells in vivo: evidence for combined action of BK and SK2 channels throughout the cochlea.Habituation of reflexive and motivated behavior in mice with deficient BK channel function.Critical role for cochlear hair cell BK channels for coding the temporal structure and dynamic range of auditory information for central auditory processingFunction and mechanism of axonal targeting of voltage-sensitive potassium channels.BK channels in innate immune functions of neutrophils and macrophages.α-Catulin CTN-1 is required for BK channel subcellular localization in C. elegans body-wall muscle cells.Alterations in cerebellar physiology are associated with a stiff-legged gait in Atcay(ji-hes) miceIncreased large conductance calcium-activated potassium (BK) channel expression accompanied by STREX variant downregulation in the developing mouse CNSCytoplasmic BK(Ca) channel intron-containing mRNAs contribute to the intrinsic excitability of hippocampal neuronsDown-regulation of BK channel expression in the pilocarpine model of temporal lobe epilepsy.BK channels control cerebellar Purkinje and Golgi cell rhythmicity in vivo.A role for BK channels in heart rate regulation in rodentsHelios expression coordinates the development of a subset of striatopallidal medium spiny neuronsInducible knockout mutagenesis reveals compensatory mechanisms elicited by constitutive BK channel deficiency in overactive murine bladder.Quantitative localization of Cav2.1 (P/Q-type) voltage-dependent calcium channels in Purkinje cells: somatodendritic gradient and distinct somatic coclustering with calcium-activated potassium channels.Concordance analysis for QTL detection in dairy cattle: a case study of leg morphology.
P2860
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P2860
Cerebellar ataxia and Purkinje cell dysfunction caused by Ca2+-activated K+ channel deficiency
description
2004 nî lūn-bûn
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2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
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2004年の論文
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2004年学术文章
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2004年学术文章
@zh-cn
2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年學術文章
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name
Cerebellar ataxia and Purkinje ...... ctivated K+ channel deficiency
@ast
Cerebellar ataxia and Purkinje ...... ctivated K+ channel deficiency
@en
Cerebellar ataxia and Purkinje ...... ctivated K+ channel deficiency
@nl
type
label
Cerebellar ataxia and Purkinje ...... ctivated K+ channel deficiency
@ast
Cerebellar ataxia and Purkinje ...... ctivated K+ channel deficiency
@en
Cerebellar ataxia and Purkinje ...... ctivated K+ channel deficiency
@nl
prefLabel
Cerebellar ataxia and Purkinje ...... ctivated K+ channel deficiency
@ast
Cerebellar ataxia and Purkinje ...... ctivated K+ channel deficiency
@en
Cerebellar ataxia and Purkinje ...... ctivated K+ channel deficiency
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
Cerebellar ataxia and Purkinje ...... ctivated K+ channel deficiency
@en
P2093
C A Sailer
D P Wolfer
H Adelsberger
M Sausbier
P2860
P304
P3181
P356
10.1073/PNAS.0401702101
P407
P577
2004-06-11T00:00:00Z