A role for ciliary neurotrophic factor as an inducer of reactive gliosis, the glial response to central nervous system injury
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The multifaceted role of astrocytes in regulating myelinationCiliary neurotrophic factor protects striatal neurons against excitotoxicity by enhancing glial glutamate uptake.The radial organization of neuronal primary cilia is acutely disrupted by seizure and ischemic brain injury.Combined suppression of CASP2 and CASP6 protects retinal ganglion cells from apoptosis and promotes axon regeneration through CNTF-mediated JAK/STAT signalling.Chronically increased ciliary neurotrophic factor and fibroblast growth factor-2 expression after spinal contusion in ratsCiliary neurotrophic factor induces genes associated with inflammation and gliosis in the retina: a gene profiling study of flow-sorted, Müller cellsChondroitin sulphate proteoglycans: preventing plasticity or protecting the CNS?Optic nerve astrocyte reactivity protects function in experimental glaucoma and other nerve injuries.STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injuryCiliary neurotrophic factor (CNTF) plus soluble CNTF receptor alpha increases cyclooxygenase-2 expression, PGE2 release and interferon-gamma-induced CD40 in murine microglia.The role of macrophages in optic nerve regeneration.Transplanted astrocytes derived from BMP- or CNTF-treated glial-restricted precursors have opposite effects on recovery and allodynia after spinal cord injury.Preconditioning-induced protection of photoreceptors requires activation of the signal-transducing receptor gp130 in photoreceptorsCiliary neurotrophic factor protects striatal output neurons in an animal model of Huntington disease.Regenerative medicine for retinal diseases: activating endogenous repair mechanisms.Expression of CNTF/LIF-receptor components and activation of STAT3 signaling in axotomized facial motoneurons: evidence for a sequential postlesional function of the cytokines.Astrocytes, therapeutic targets for neuroprotection and neurorestoration in ischemic stroke.Astrocytes: a central element in neurological diseases.Evidence that remodeling of insular cortex neurovascular unit contributes to hypertension-related sympathoexcitation.CNTF promotes the survival and differentiation of adult spinal cord-derived oligodendrocyte precursor cells in vitro but fails to promote remyelination in vivo.Ciliary neurotrophic factor protects mice against streptozotocin-induced type 1 diabetes through SOCS3: the role of STAT1/STAT3 ratio in β-cell death.Identification of a novel gp130-responsive site in the vasoactive intestinal peptide cytokine response element.Alanine substitution for Thr268 and Asp269 of soluble ciliary neurotrophic factor (CNTF) receptor alpha component defines a specific antagonist for the CNTF response.Expression of ciliary neurotrophic factor (CNTF) and its tripartite receptor complex by cells of the human optic nerve head.Astrocytic alterations in interleukin-6/Soluble interleukin-6 receptor alpha double-transgenic mice.Neuroprotective effect of interleukin-6 and IL6/IL6R chimera in the quinolinic acid rat model of Huntington's syndrome.Quinolinic acid lesions of the caudate putamen in the rat lead to a local increase of ciliary neurotrophic factor.Diversity of astroglial responses across human neurodegenerative disorders and brain aging.Exogenous ciliary neurotrophic factor (CNTF) reduces synaptic depression during repetitive stimulation.The anorexigenic cytokine ciliary neurotrophic factor stimulates POMC gene expression via receptors localized in the nucleus of arcuate neurons.
P2860
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P2860
A role for ciliary neurotrophic factor as an inducer of reactive gliosis, the glial response to central nervous system injury
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
A role for ciliary neurotrophi ...... central nervous system injury
@ast
A role for ciliary neurotrophi ...... central nervous system injury
@en
A role for ciliary neurotrophi ...... central nervous system injury
@nl
type
label
A role for ciliary neurotrophi ...... central nervous system injury
@ast
A role for ciliary neurotrophi ...... central nervous system injury
@en
A role for ciliary neurotrophi ...... central nervous system injury
@nl
prefLabel
A role for ciliary neurotrophi ...... central nervous system injury
@ast
A role for ciliary neurotrophi ...... central nervous system injury
@en
A role for ciliary neurotrophi ...... central nervous system injury
@nl
P2093
P2860
P356
P1476
A role for ciliary neurotrophi ...... central nervous system injury
@en
P2093
P2860
P304
P356
10.1073/PNAS.92.13.5865
P407
P577
1995-06-20T00:00:00Z