Brn-3.0: a POU-domain protein expressed in the sensory, immune, and endocrine systems that functions on elements distinct from known octamer motifs
about
Inhibition of neuronal process outgrowth and neuronal specific gene activation by the Brn-3b transcription factorLate-emigrating neural crest cells in the roof plate are restricted to a sensory fate by GDF7.POU transcription factors Brn-3a and Brn-3b interact with the estrogen receptor and differentially regulate transcriptional activity via an estrogen response elementThe pituitary V3 vasopressin receptor and the corticotroph phenotype in ectopic ACTH syndromeTargeted deletion of the mouse POU domain gene Brn-3a causes selective loss of neurons in the brainstem and trigeminal ganglion, uncoordinated limb movement, and impaired sucklingP-OTX: a PIT-1-interacting homeodomain factor expressed during anterior pituitary gland developmentThe DFNA15 deafness mutation affects POU4F3 protein stability, localization, and transcriptional activityFunctional interaction between the small GTP-binding protein Rin and the N-terminal of Brn-3a transcription factorBrn3a is a transcriptional regulator of soma size, target field innervation and axon pathfinding of inner ear sensory neuronsThe different activities of the two activation domains of the Brn-3a transcription factor are dependent on the context of the binding siteThe ability of POU family transcription factors to activate or repress gene expression is dependent on the spacing and context of their specific response elementsEssential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development.The Brn-3a transcription factor induces neuronal process outgrowth and the coordinate expression of genes encoding synaptic proteinsThe BRN-3A transcription factor protects sensory but not sympathetic neurons from programmed cell death/apoptosisThe opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domainShort isoform of POU factor Brn-3b can form a heterodimer with Brn-3a that is inactive for octamer motif bindingConditional and inducible gene recombineering in the mouse inner earMolecular biology of retinal ganglion cells.Birthdays of retinal amacrine cell subtypes are systematically related to their molecular identity and soma positionRegulation of DNA virus transcription by cellular POU family transcription factors.Distinct functions of acj6 splice forms in odor receptor gene choiceThe Brn-3b POU family transcription factor regulates the cellular growth, proliferation, and anchorage dependence of MCF7 human breast cancer cells.Proneural and proneuroendocrine transcription factor expression in cutaneous mechanoreceptor (Merkel) cells and Merkel cell carcinoma.Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors.Post-transcriptional regulation of the Brn-3b transcription factor in differentiating neuroblastoma cells.The N-terminal domain unique to the long form of the Brn-3a transcription factor is essential to protect neuronal cells from apoptosis and for the activation of Bbcl-2 gene expression.Transcription factors interacting with herpes simplex virus alpha gene promoters in sensory neuronsGenetic interactions between Brn3 transcription factors in retinal ganglion cell type specification.Activation of Six1 Expression in Vertebrate Sensory Neurons.Brn3a/Pou4f1 regulates dorsal root ganglion sensory neuron specification and axonal projection into the spinal cord.Transcription Factor Brn-3b Overexpression Enhances Neurite Outgrowth in PC12 Cells Under Condition of Hypoxia.Lineage-specific requirements of beta-catenin in neural crest development.Distinct variant DNA-binding sites determine cell-specific autoregulated expression of the Drosophila POU domain transcription factor drifter in midline glia or trachea.The POU domain of SCIP/Tst-1/Oct-6 is sufficient for activation of an acetylcholine receptor promoter.POU domain factors of the Brn-3 class recognize functional DNA elements which are distinctive, symmetrical, and highly conserved in evolutionMissense mutations in POU4F3 cause autosomal dominant hearing impairment DFNA15 and affect subcellular localization and DNA bindingSimilar DNA recognition properties of alternatively spliced Drosophila POU factors.The neural crest transcription factor Brn3a is expressed in melanoma and required for cell cycle progression and survival.Biomarkers in cervical precancer management: the new frontiers.POU domain factor Brn-3a controls the differentiation and survival of trigeminal neurons by regulating Trk receptor expression
P2860
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P2860
Brn-3.0: a POU-domain protein expressed in the sensory, immune, and endocrine systems that functions on elements distinct from known octamer motifs
description
1993 nî lūn-bûn
@nan
1993 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
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name
Brn-3.0: a POU-domain protein ...... inct from known octamer motifs
@ast
Brn-3.0: a POU-domain protein ...... inct from known octamer motifs
@en
Brn-3.0: a POU-domain protein ...... inct from known octamer motifs
@nl
type
label
Brn-3.0: a POU-domain protein ...... inct from known octamer motifs
@ast
Brn-3.0: a POU-domain protein ...... inct from known octamer motifs
@en
Brn-3.0: a POU-domain protein ...... inct from known octamer motifs
@nl
prefLabel
Brn-3.0: a POU-domain protein ...... inct from known octamer motifs
@ast
Brn-3.0: a POU-domain protein ...... inct from known octamer motifs
@en
Brn-3.0: a POU-domain protein ...... inct from known octamer motifs
@nl
P2093
P2860
P356
P1476
Brn-3.0: a POU-domain protein ...... inct from known octamer motifs
@en
P2093
M G Rosenfeld
M R Gerrero
R J McEvilly
S O'Connell
P2860
P304
P356
10.1073/PNAS.90.22.10841
P407
P577
1993-11-15T00:00:00Z