Platelet-derived growth factor mimics phorbol diester action on epidermal growth factor receptor phosphorylation at threonine-654
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Phosphorylation process induced by epidermal growth factor alters the oncogenic and cellular neu (NGL) gene products.Phosphorylation at threonine-654 is not required for negative regulation of the epidermal growth factor receptor by non-phorbol tumor promoters.The role of EGF receptor transmodulation in embryonal carcinoma-derived growth factor-induced mitogenesisPlatelet-derived growth factor modulates epidermal growth factor receptors by a mechanism distinct from that of phorbol esters.Stimulation of phosphorylation of lipocortin at threonine residues by epidermal growth factor (EGF) and the EGF receptor: addition of protein kinase P with polylysine inhibits this effectEffect of protein kinase P on phosphorylations catalyzed by the epidermal growth factorPlatelet-derived growth factor stimulates phagocytosis and blocks agonist-induced activation of the neutrophil oxidative burst: a possible cellular mechanism to protect against oxygen radical damage.Mitogenic signaling pathways of growth factors can be distinguished by the involvement of pertussis toxin-sensitive guanosine triphosphate-binding protein and of protein kinase C.Oncogenic activation of p185neu stimulates tyrosine phosphorylation in vivoModulation of the membrane type 1 matrix metalloproteinase cytoplasmic tail enhances tumor cell invasion and proliferation in three-dimensional collagen matrices.Annexin A6 is a scaffold for PKCα to promote EGFR inactivation.Anisomycin selectively desensitizes signalling components involved in stress kinase activation and fos and jun induction.Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types.Human cancer cells exhibit protein kinase C-dependent c-erbB-2 transmodulation that correlates with phosphatase sensitivity and kinase activity.Basolateral EGF receptor sorting regulated by functionally distinct mechanisms in renal epithelial cells.Analysis of epidermal growth factor (EGF) receptor and effect of EGF on the growth of cultured Graves' and non-neoplastic human thyroid cells.Phenytoin increases gene expression for platelet-derived growth factor B chain in macrophages and monocytes.
P2860
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P2860
Platelet-derived growth factor mimics phorbol diester action on epidermal growth factor receptor phosphorylation at threonine-654
description
1985 nî lūn-bûn
@nan
1985 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1985 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1985年の論文
@ja
1985年論文
@yue
1985年論文
@zh-hant
1985年論文
@zh-hk
1985年論文
@zh-mo
1985年論文
@zh-tw
1985年论文
@wuu
name
Platelet-derived growth factor ...... osphorylation at threonine-654
@ast
Platelet-derived growth factor ...... osphorylation at threonine-654
@en
Platelet-derived growth factor ...... osphorylation at threonine-654
@nl
type
label
Platelet-derived growth factor ...... osphorylation at threonine-654
@ast
Platelet-derived growth factor ...... osphorylation at threonine-654
@en
Platelet-derived growth factor ...... osphorylation at threonine-654
@nl
prefLabel
Platelet-derived growth factor ...... osphorylation at threonine-654
@ast
Platelet-derived growth factor ...... osphorylation at threonine-654
@en
Platelet-derived growth factor ...... osphorylation at threonine-654
@nl
P2860
P356
P1476
Platelet-derived growth factor ...... osphorylation at threonine-654
@en
P2093
P2860
P304
P356
10.1073/PNAS.82.12.4080
P407
P577
1985-06-01T00:00:00Z