Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes
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PhenoImageShare: an image annotation and query infrastructureContributions of Mammalian Chimeras to Pluripotent Stem Cell ResearchReporting phenotypes in mouse models when considering body size as a potential confounderGermline Modification and Engineering in Avian SpeciesMouse Genome Informatics (MGI): reflecting on 25 yearsA 660-Kb deletion with antagonistic effects on fertility and milk production segregates at high frequency in Nordic Red cattle: additional evidence for the common occurrence of balancing selection in livestockMultiple knockout mouse models reveal lincRNAs are required for life and brain developmentRapid phenotyping of knockout mice to identify genetic determinants of bone strengthA drosophila genetic resource of mutants to study mechanisms underlying human genetic diseasesThe Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular MorphogenesisNovel skin phenotypes revealed by a genome-wide mouse reverse genetic screen.Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screenIdentification of genes important for cutaneous function revealed by a large scale reverse genetic screen in the mouseSearch for the Function of NWC, Third Gene Within RAG Locus: Generation and Characterization of NWC-Deficient MiceIntegrating EMR-linked and in vivo functional genetic data to identify new genotype-phenotype associationsDevelopmental regulation of planar cell polarity and hair-bundle morphogenesis in auditory hair cells: lessons from human and mouse genetics.Wbp2 is required for normal glutamatergic synapses in the cochlea and is crucial for hearing.Usher syndrome: Hearing loss, retinal degeneration and associated abnormalities.Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinicsFunctional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells.ILDR1 null mice, a model of human deafness DFNB42, show structural aberrations of tricellular tight junctions and degeneration of auditory hair cells.Phenotype ontologies and cross-species analysis for translational researchThe International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping dataRapid Knockout and Reporter Mouse Line Generation and Breeding Colony Establishment Using EUCOMM Conditional-Ready Embryonic Stem Cells: A Case StudyA gene expression resource generated by genome-wide lacZ profiling in the mouse.Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death.Combining RNA and protein profiling data with network interactions identifies genes associated with spermatogenesis in mouse and human.PhenStat: A Tool Kit for Standardized Analysis of High Throughput Phenotypic Data.Allelome.PRO, a pipeline to define allele-specific genomic features from high-throughput sequencing data.Dissecting mammalian immunity through mutation.The role of sex and body weight on the metabolic effects of high-fat diet in C57BL/6N miceGenome-wide in vivo screen identifies host molecule in promoting cancer metastasisUsing association rule mining to determine promising secondary phenotyping hypothesesNext-generation mammalian genetics toward organism-level systems biologySystematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes.Systems biology for hepatologists.Analysis of stop-gain and frameshift variants in human innate immunity genes.Hira-mediated H3.3 incorporation is required for DNA replication and ribosomal RNA transcription in the mouse zygoteQuantitative assessment of the multiple processes responsible for bilirubin homeostasis in health and disease.
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P2860
Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes
description
2013 nî lūn-bûn
@nan
2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Genome-wide generation and sys ...... veals new roles for many genes
@ast
Genome-wide generation and sys ...... veals new roles for many genes
@en
Genome-wide generation and sys ...... veals new roles for many genes
@nl
type
label
Genome-wide generation and sys ...... veals new roles for many genes
@ast
Genome-wide generation and sys ...... veals new roles for many genes
@en
Genome-wide generation and sys ...... veals new roles for many genes
@nl
prefLabel
Genome-wide generation and sys ...... veals new roles for many genes
@ast
Genome-wide generation and sys ...... veals new roles for many genes
@en
Genome-wide generation and sys ...... veals new roles for many genes
@nl
P2093
P2860
P50
P921
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Genome-wide generation and sys ...... veals new roles for many genes
@en
P2093
Allan Bradley
Anna-Karin Gerdin
Christine Podrini
Daniel G Macarthur
David G Melvin
David J Adams
David Sunter
Jacqueline K White
P2860
P304
P3181
P356
10.1016/J.CELL.2013.06.022
P407
P577
2013-07-18T00:00:00Z