The (6;9) chromosome translocation, associated with a specific subtype of acute nonlymphocytic leukemia, leads to aberrant transcription of a target gene on 9q34
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The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNACan, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set geneThe SAF-box domain of chromatin protein DEKMolecular genetic aspects of human cancers: the 1993 Frank Rose Lecture.Intercellular trafficking of the nuclear oncoprotein DEK.Proteomic analysis of apoptosis related proteins regulated by proto-oncogene protein DEK.Cre-mediated site-specific translocation between nonhomologous mouse chromosomesHigh-affinity interaction of poly(ADP-ribose) and the human DEK oncoprotein depends upon chain length.Molecular biology in medicine.SET-CAN, the product of the t(9;9) in acute undifferentiated leukemia, causes expansion of early hematopoietic progenitors and hyperproliferation of stomach mucosa in transgenic mice.Mouse chromosome engineering for modeling human disease.The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia.t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1.Development of a D-FISH method to detect DEK/CAN fusion resulting from t(6;9)(p23;q34) in patients with acute myelogenous leukemia.A role for intracellular and extracellular DEK in regulating hematopoiesis.Biologic indicators of exposure: are markers associated with oncogenesis useful as biologic markers of effect?Effects of SET and SET-CAN on the differentiation of the human promonocytic cell line U937.Detection of chromosomal translocations in leukemia-lymphoma cells by polymerase chain reaction.Establishment of a novel human myeloid leukaemia cell line (FKH-1) with t(6;9)(p23;q34) and the expression of dek-can chimaeric transcript.Sublocalization of the chromosome 5 breakpoint of the 3;5 translocation in myelodysplastic syndromes and acute myeloid leukemia.The Oncogenic Fusion Proteins SET-Nup214 and Sequestosome-1 (SQSTM1)-Nup214 Form Dynamic Nuclear Bodies and Differentially Affect Nuclear Protein and Poly(A)+ RNA Export.A t(10;17) translocation creates the RET/PTC2 chimeric transforming sequence in papillary thyroid carcinoma.DEK-CAN molecular monitoring of myeloid malignancies could aid therapeutic stratification.A DEK domain-containing protein modulates chromatin structure and function in Arabidopsis.Growth characteristics in vitro of myeloid leukaemic cells with t(6;9).Characterization of the translocation breakpoint sequences of two DEK-CAN fusion genes present in t(6;9) acute myeloid leukemia and a SET-CAN fusion gene found in a case of acute undifferentiated leukemia.DEK-NUP214-Fusion Identified by RNA-Sequencing of an Acute Myeloid Leukemia with t(9;12)(q34;q15).Whole-exome sequence analysis highlights the role of unmasked recessive mutations in copy number variants with incomplete penetrance.Acute Myeloid Leukemia
P2860
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P2860
The (6;9) chromosome translocation, associated with a specific subtype of acute nonlymphocytic leukemia, leads to aberrant transcription of a target gene on 9q34
description
1990 nî lūn-bûn
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1990 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1990年の論文
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1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
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name
The (6;9) chromosome transloca ...... ption of a target gene on 9q34
@ast
The (6;9) chromosome transloca ...... ption of a target gene on 9q34
@en
The (6;9) chromosome transloca ...... ption of a target gene on 9q34
@nl
type
label
The (6;9) chromosome transloca ...... ption of a target gene on 9q34
@ast
The (6;9) chromosome transloca ...... ption of a target gene on 9q34
@en
The (6;9) chromosome transloca ...... ption of a target gene on 9q34
@nl
prefLabel
The (6;9) chromosome transloca ...... ption of a target gene on 9q34
@ast
The (6;9) chromosome transloca ...... ption of a target gene on 9q34
@en
The (6;9) chromosome transloca ...... ption of a target gene on 9q34
@nl
P2093
P2860
P356
P1476
The (6;9) chromosome transloca ...... ption of a target gene on 9q34
@en
P2093
G Grosveld
M von Lindern
P2860
P304
P356
10.1128/MCB.10.8.4016
P407
P577
1990-08-01T00:00:00Z