DNA synthesis at individual replication forks requires the essential initiation factor Cdc45p
about
A vertebrate gene, ticrr, is an essential checkpoint and replication regulatorTreslin collaborates with TopBP1 in triggering the initiation of DNA replicationPSF1 is essential for early embryogenesis in miceSld3, which interacts with Cdc45 (Sld4), functions for chromosomal DNA replication in Saccharomyces cerevisiaeDistinct roles for Sld3 and GINS during establishment and progression of eukaryotic DNA replication forksBinding of cyclin-dependent kinases to ORC and Cdc6p regulates the chromosome replication cycleA requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replicationHow do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells?Activation of the DNA damage checkpoint in mutants defective in DNA replication initiationGlobal effects of DNA replication and DNA replication origin activity on eukaryotic gene expressionGINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeastTackling an essential problem in functional proteomics of Saccharomyces cerevisiaeWhither genomics?Archaeal MCM Proteins as an Analog for the Eukaryotic Mcm2-7 Helicase to Reveal Essential Features of Structure and FunctionMechanisms for initiating cellular DNA replicationBreak-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly.Separate roles for the DNA damage checkpoint protein kinases in stabilizing DNA replication forks.Mcm10 associates with the loaded DNA helicase at replication origins and defines a novel step in its activation.Cdc45 protein-single-stranded DNA interaction is important for stalling the helicase during replication stress.Interactions between Mcm10p and other replication factors are required for proper initiation and elongation of chromosomal DNA replication in Saccharomyces cerevisiae.A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha within the eukaryotic replisome.Mrc1 and Tof1 regulate DNA replication forks in different ways during normal S phaseHuman Dbf4/ASK promoter is activated through the Sp1 and MluI cell-cycle box (MCB) transcription elementsTimeless preserves telomere length by promoting efficient DNA replication through human telomeresRegulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpointCdc45 limits replicon usage from a low density of preRCs in mammalian cellsChromatin decondensation in S-phase involves recruitment of Cdk2 by Cdc45 and histone H1 phosphorylationXic1 degradation in Xenopus egg extracts is coupled to initiation of DNA replication.Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakageReplisome instability, fork collapse, and gross chromosomal rearrangements arise synergistically from Mec1 kinase and RecQ helicase mutations.A strategy for interaction site prediction between phospho-binding modules and their partners identified from proteomic dataThe DNA unwinding element binding protein DUE-B interacts with Cdc45 in preinitiation complex formation.Localisation of the DmCdc45 DNA replication factor in the mitotic cycle and during chorion gene amplificationRequirement of CDC45 for postimplantation mouse developmentCdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progressionMultifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes.The ATPase activity of MCM2-7 is dispensable for pre-RC assembly but is required for DNA unwinding.Regulation of origin recognition complex conformation and ATPase activity: differential effects of single-stranded and double-stranded DNA bindingControl of DNA replication licensing in a cell cycle.Replication licensing and the DNA damage checkpoint.
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P2860
DNA synthesis at individual replication forks requires the essential initiation factor Cdc45p
description
2000 nî lūn-bûn
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2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2000 թվականի մայիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
DNA synthesis at individual re ...... ntial initiation factor Cdc45p
@ast
DNA synthesis at individual re ...... ntial initiation factor Cdc45p
@en
DNA synthesis at individual re ...... ntial initiation factor Cdc45p
@nl
type
label
DNA synthesis at individual re ...... ntial initiation factor Cdc45p
@ast
DNA synthesis at individual re ...... ntial initiation factor Cdc45p
@en
DNA synthesis at individual re ...... ntial initiation factor Cdc45p
@nl
prefLabel
DNA synthesis at individual re ...... ntial initiation factor Cdc45p
@ast
DNA synthesis at individual re ...... ntial initiation factor Cdc45p
@en
DNA synthesis at individual re ...... ntial initiation factor Cdc45p
@nl
P2093
P2860
P3181
P356
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DNA synthesis at individual re ...... ntial initiation factor Cdc45p
@en
P2093
P2860
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10.1093/EMBOJ/19.9.2082
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P577
2000-05-02T00:00:00Z