about
Ovarian Cancer and BRCA1/2 Testing: Opportunities to Improve Clinical Care and Disease PreventionThe BRCA1 Breast Cancer Suppressor: Regulation of Transport, Dynamics, and Function at Multiple Subcellular LocationsBeyond DNA: An Integrated and Functional Approach for Classifying Germline Variants in Breast Cancer GenesDistinct implications of different BRCA mutations: efficacy of cytotoxic chemotherapy, PARP inhibition and clinical outcome in ovarian cancerConnection between Tumor Suppressor BRCA1 and PTEN in Damaged DNA RepairA unified analytic framework for prioritization of non-coding variants of uncertain significance in heritable breast and ovarian cancer.Functional and structural analysis of C-terminal BRCA1 missense variants.The breast cancer susceptibility genes (BRCA) in breast and ovarian cancers.The BRCA1 tumor suppressor binds to inositol 1,4,5-trisphosphate receptors to stimulate apoptotic calcium release.Artemisinin mimics calorie restriction to trigger mitochondrial biogenesis and compromise telomere shortening in micePhase I Study of Single-Agent AZD1775 (MK-1775), a Wee1 Kinase Inhibitor, in Patients With Refractory Solid Tumors.Polymorphisms in the p63 and p73 genes are associated with ovarian cancer risk and clinicopathological variables"DNA Binding Region" of BRCA1 Affects Genetic Stability through modulating the Intra-S-Phase CheckpointBRCA1-hapoinsufficiency: Unraveling the molecular and cellular basis for tissue-specific cancerCombined genetic and splicing analysis of BRCA1 c.[594-2A>C; 641A>G] highlights the relevance of naturally occurring in-frame transcripts for developing disease gene variant classification algorithms.Identification of recurrent BRCA1 mutation and its clinical relevance in Chinese Triple-negative breast cancer cohort.Germline missense pathogenic variants in the BRCA1 BRCT domain, p.Gly1706Glu and p.Ala1708Glu, increase cellular sensitivity to PARP inhibitor olaparib by a dominant negative effect.BRCA1 recruitment to damaged DNA sites is dependent on CDK9.BRCA1 exon 11 a model of long exon splicing regulation.Expression of cancer related BRCA1 missense variants decreases MMS-induced recombination in Saccharomyces cerevisiae without altering its nuclear localization.Analysis of BRCA1/2 mutation spectrum and prevalence in unselected Chinese breast cancer patients by next-generation sequencing.Novel BRCA1 splice-site mutation in ovarian cancer patients of Slavic origin.Role of BRCA Mutations in the Modulation of Response to Platinum Therapy.Gene-Specific Genetic Complementation between Brca1 and Cobra1 During Mouse Mammary Gland Development.Karyopherins in cancer.Low concentrations of antimony impair DNA damage signaling and the repair of radiation-induced DSB in HeLa S3 cells.
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
STRUCTURE-FUNCTION OF THE TUMOR SUPPRESSOR BRCA1
@ast
STRUCTURE-FUNCTION OF THE TUMOR SUPPRESSOR BRCA1
@en
STRUCTURE-FUNCTION OF THE TUMOR SUPPRESSOR BRCA1
@nl
type
label
STRUCTURE-FUNCTION OF THE TUMOR SUPPRESSOR BRCA1
@ast
STRUCTURE-FUNCTION OF THE TUMOR SUPPRESSOR BRCA1
@en
STRUCTURE-FUNCTION OF THE TUMOR SUPPRESSOR BRCA1
@nl
prefLabel
STRUCTURE-FUNCTION OF THE TUMOR SUPPRESSOR BRCA1
@ast
STRUCTURE-FUNCTION OF THE TUMOR SUPPRESSOR BRCA1
@en
STRUCTURE-FUNCTION OF THE TUMOR SUPPRESSOR BRCA1
@nl
P2093
P2860
P3181
P356
P1476
Structure-Function Of The Tumor Suppressor BRCA1
@en
P2093
Ana M Rodriguez
Gary D V Hankins
Russell R Snyder
Serena L Clark
P2860
P3181
P356
10.5936/CSBJ.201204005
P577
2012-04-01T00:00:00Z