Computer-based identification of a novel LIMK1/2 inhibitor that synergizes with salirasib to destabilize the actin cytoskeleton
about
Advances in targeting signal transduction pathwaysDownregulation of microRNA-23a suppresses prostate cancer metastasis by targeting the PAK6-LIMK1 signaling pathwayDiscovery of Novel Small-Molecule Inhibitors of LIM Domain Kinase for Inhibiting HIV-1JG6, a novel marine-derived oligosaccharide, suppresses breast cancer metastasis via binding to cofilin.The NF1 gene revisited - from bench to bedside.Novel LIMK2 Inhibitor Blocks Panc-1 Tumor Growth in a mouse xenograft modelBis-aryl urea derivatives as potent and selective LIM kinase (Limk) inhibitors.Nitric oxide enhances keratinocyte cell migration by regulating Rho GTPase via cGMP-PKG signallingEvidence for the involvement of cofilin in Aspergillus fumigatus internalization into type II alveolar epithelial cells.LIM kinase inhibitors disrupt mitotic microtubule organization and impair tumor cell proliferation.Reduced LIMK2 expression in colorectal cancer reflects its role in limiting stem cell proliferation.Enhancing FTS (Salirasib) efficiency via combinatorial treatment.LIM kinases: cofilin and beyond.Molecular pathways: targeting the kinase effectors of RHO-family GTPases.Targeting LIM kinase in cancer and neurofibromatosis.High expression of Rac1 is correlated with partial reversed cell polarity and poor prognosis in invasive ductal carcinoma of the breast.VEGF Triggers the Activation of Cofilin and the Arp2/3 Complex within the Growth Cone.Quercetin Has Antimetastatic Effects on Gastric Cancer Cells via the Interruption of uPA/uPAR Function by Modulating NF-κb, PKC-δ, ERK1/2, and AMPKα.ROCK inhibition prevents early mouse embryo development.
P2860
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P2860
Computer-based identification of a novel LIMK1/2 inhibitor that synergizes with salirasib to destabilize the actin cytoskeleton
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Computer-based identification ...... abilize the actin cytoskeleton
@ast
Computer-based identification ...... abilize the actin cytoskeleton
@en
Computer-based identification ...... abilize the actin cytoskeleton
@nl
type
label
Computer-based identification ...... abilize the actin cytoskeleton
@ast
Computer-based identification ...... abilize the actin cytoskeleton
@en
Computer-based identification ...... abilize the actin cytoskeleton
@nl
prefLabel
Computer-based identification ...... abilize the actin cytoskeleton
@ast
Computer-based identification ...... abilize the actin cytoskeleton
@en
Computer-based identification ...... abilize the actin cytoskeleton
@nl
P2093
P2860
P356
P1433
P1476
Computer-based identification ...... abilize the actin cytoskeleton
@en
P2093
Efrat Mashiach-Farkash
Galit Elad-Sfadia
Haim J Wolfson
Roni Haklai
Shmuel Carmeli
Yoel Kloog
P2860
P304
P356
10.18632/ONCOTARGET.525
P407
P577
2012-06-01T00:00:00Z