Antibodies specific for a segment of human membrane IgE deplete IgE-producing B cells in humanized mice - Wikidata - wikimedia - TriplyDB

Antibodies specific for a segment of human membrane IgE deplete IgE-producing B cells in humanized mice

Antibodies specific for a segment of human membrane IgE deplete IgE-producing B cells in humanized mice

http://www.wikidata.org/entity/Q24604440

about

Defining severe asthma - an approach to find new therapies Regulatory constraints in the generation and differentiation of IgE-expressing B cells Two potential therapeutic antibodies bind to a peptide segment of membrane-bound IgE in different conformations Antibody modeling assessment II. Structures and models AID-induced remodeling of immunoglobulin genes and B cell fate.The IgE gene in primates exhibits extraordinary evolutionary diversity.Targeting membrane-expressed IgE B cell receptor with an antibody to the M1 prime epitope reduces IgE production.Memory B cells.Structural and Physical Basis for Anti-IgE Therapy.The Extracellular Domains of IgG1 and T Cell-Derived IL-4/IL-13 Are Critical for the Polyclonal Memory IgE Response In Vivo Cytokinergic IgE Action in Mast Cell Activation.Inositol 1,4,5-trisphosphate activates TRPC3 channels to cause extracellular Ca2+ influx in airway smooth muscle cells A randomized trial of the efficacy and safety of quilizumab in adults with inadequately controlled allergic asthma.Ontogeny of human IgE-expressing B cells and plasma cells Food allergy: Insights into etiology, prevention, and treatment provided by murine models.The role of monoclonal antibodies in the treatment of severe asthma.Monoclonal antibodies for asthma and chronic obstructive pulmonary disease.Lymphocyte-based model systems for allergy research: a historic overview.Emerging biologics for the treatment of chronic rhinosinusitis.The future of biologics: applications for food allergy.Asthma phenotyping: a necessity for improved therapeutic precision and new targeted therapies.From IgE to Omalizumab.Treating IgE-mediated diseases via targeting IgE-expressing B cells using an anti-CεmX antibody.New roots for IgE-producing B cells.Enhanced cell-binding by allergen multimers: how complex is it?B Cell Intrinsic Mechanisms Constraining IgE Memory.IgE⁺ memory B cells and plasma cells generated through a germinal-center pathway.The majority of allergen-specific IgE in the blood of allergic patients does not originate from blood-derived B cells or plasma cells.On the differentiation of mouse IgE⁺ cells.IgE class switching and cellular memory.Chimeric Antigen Receptors Based on Low Affinity Mutants of FcεRI Re-direct T Cell Specificity to Cells Expressing Membrane IgE Potential Pitfalls of the Humanized Mice in Modeling Sepsis

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P2860

Antibodies specific for a segment of human membrane IgE deplete IgE-producing B cells in humanized mice

http://www.wikidata.org/entity/Q24604440

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Antibodies specific for a segm ...... cing B cells in humanized mice

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Antibodies specific for a segm ...... cing B cells in humanized mice

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Antibodies specific for a segm ...... cing B cells in humanized mice

@nl

type

label

Antibodies specific for a segm ...... cing B cells in humanized mice

@ast

Antibodies specific for a segm ...... cing B cells in humanized mice

@en

Antibodies specific for a segm ...... cing B cells in humanized mice

@nl

prefLabel

Antibodies specific for a segm ...... cing B cells in humanized mice

@ast

Antibodies specific for a segm ...... cing B cells in humanized mice

@en

Antibodies specific for a segm ...... cing B cells in humanized mice

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P1433

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P2860

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P1433

Journal of Clinical Investigation

P1476

Antibodies specific for a segm ...... cing B cells in humanized mice

@en

P2093

Allen Nguyen

http://www.w3.org/2001/XMLSchema#string

Anan Chuntharapai

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Canio J Refino

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Donghong Yan

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Donnie Delarosa

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Elizabeth Luis

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Hans D Brightbill

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Janet Jackman

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Laura DeForge

http://www.w3.org/2001/XMLSchema#string

Lawren C Wu

http://www.w3.org/2001/XMLSchema#string

P2860

The effect of intravenous administration of a chimeric anti-IgE antibody on serum IgE levels in atopic subjects: efficacy, safety, and pharmacokinetics

Death by a B cell superantigen: In vivo VH-targeted apoptotic supraclonal B cell deletion by a Staphylococcal Toxin

X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling

Pushing the boundaries of molecular replacement with maximum likelihood

Refinement of macromolecular structures by the maximum-likelihood method

The CCP4 suite: programs for protein crystallography

Anti-IgE antibodies for the treatment of IgE-mediated allergic diseases

Inhibition of IgE synthesis by anti-IgE: role in long-term inhibition of IgE synthesis by neonatally administered soluble IgE.

Immunoglobulin switch circular DNA in the mouse infected with Nippostrongylus brasiliensis: evidence for successive class switching from mu to epsilon via gamma 1.

Suppression of IgE B cells and IgE binding to Fc(epsilon)RI by gene therapy with single-chain anti-IgE.

P304

2218-29

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scholarly article

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4908327

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P356

10.1172/JCI40141

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P433

6

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120

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Charles Eigenbrot

Mercedesz Balazs

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2010-06-01T00:00:00Z

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20458139

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2877936

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