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Metabolic insight into mechanisms of high-altitude adaptation in Tibetans

Metabolic insight into mechanisms of high-altitude adaptation in Tibetans

http://www.wikidata.org/entity/Q24605065

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Metabolic basis to Sherpa altitude adaptation A genetic mechanism for Tibetan high-altitude adaptation.Genomic analysis of natural selection and phenotypic variation in high-altitude mongolians.Shared and unique signals of high-altitude adaptation in geographically distinct Tibetan populations Novel genomic signals of recent selection in an Ethiopian population.Glucose homeostasis during short-term and prolonged exposure to high altitudes.Altitude Adaptation: A Glimpse Through Various Lenses.A Genome-Wide Search for Greek and Jewish Admixture in the Kashmiri Population.Glucose intolerance associated with hypoxia in people living at high altitudes in the Tibetan highland.Regulation of erythropoiesis by hypoxia-inducible factors On the pivotal role of PPARα in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury.Sherpas share genetic variations with Tibetans for high-altitude adaptation.PPAR-α as a key nutritional and environmental sensor for metabolic adaptation.Phenotypic plasticity and epigenetic marking: an assessment of evidence for genetic accommodation.'Ome' on the range: update on high-altitude acclimatization/adaptation and disease.Metabolic aspects of high-altitude adaptation in Tibetans.Differential expression of genes related to glucose metabolism in domesticated pigs and wild boar.Diabetes in Immigrant Tibetan Muslims in Kashmir, North India.Comparative analysis of the microRNA transcriptome between yak and cattle provides insight into high-altitude adaptation.Osteocalcin is inversely associated with glucose levels in middle-aged Tibetan men with different degrees of glucose tolerance.Human Genetic Adaptation to High Altitudes: Current Status and Future Prospects.The prevalence of and risk factors for diabetes mellitus and impaired glucose tolerance among Tibetans in China: a cross-sectional study.Lower mitochondrial DNA content relates to high-altitude adaptation in Tibetans

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P2860

Metabolic insight into mechanisms of high-altitude adaptation in Tibetans

http://www.wikidata.org/entity/Q24605065

description

2012 nî lūn-bûn

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2012 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2012 թվականի հունիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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Metabolic insight into mechanisms of high-altitude adaptation in Tibetans

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Metabolic insight into mechanisms of high-altitude adaptation in Tibetans

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Metabolic insight into mechanisms of high-altitude adaptation in Tibetans

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Metabolic insight into mechanisms of high-altitude adaptation in Tibetans

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Metabolic insight into mechanisms of high-altitude adaptation in Tibetans

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Metabolic insight into mechanisms of high-altitude adaptation in Tibetans

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Molecular Genetics and Metabolism

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Metabolic insight into mechanisms of high-altitude adaptation in Tibetans

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Bai Zhengzhong

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Chad D Huff

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David J Witherspoon

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Josef T Prchal

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Ri-Li Ge

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Robert C Cooksey

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Tatum S Simonson

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Uran Tanna

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P2860

Identifying signatures of natural selection in Tibetan and Andean populations using dense genome scan data

Genetic adaptation to high altitude in the Ethiopian highlands

On the origin of Tibetans and their genetic basis in adapting high-altitude environments

A map of recent positive selection in the human genome

Genome-wide detection and characterization of positive selection in human populations

Sequencing of 50 human exomes reveals adaptation to high altitude

Regulation of human metabolism by hypoxia-inducible factor

Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders

Hypoxia-inducible factors and the response to hypoxic stress

Phenotypic plasticity and genetic adaptation to high-altitude hypoxia in vertebrates

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