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Tunable and multifunctional eukaryotic transcription factors based on CRISPR/Cas

Tunable and multifunctional eukaryotic transcription factors based on CRISPR/Cas

http://www.wikidata.org/entity/Q24606465

about

Beyond editing: repurposing CRISPR-Cas9 for precision genome regulation and interrogation Enabling functional genomics with genome engineering Synthetic analog and digital circuits for cellular computation and memory Electroporation Knows No Boundaries: The Use of Electrostimulation for siRNA Delivery in Cells and Tissues Single molecule fluorescence approaches shed light on intracellular RNAs Making designer mutants in model organisms How to train your microbe: methods for dynamically characterizing gene networks A Biophysical Model of CRISPR/Cas9 Activity for Rational Design of Genome Editing and Gene Regulation A protein-tagging system for signal amplification in gene expression and fluorescence imaging.Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells.Regulation of endogenous human gene expression by ligand-inducible TALE transcription factors.Rule-based design of synthetic transcription factors in eukaryotes.Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers.Enhanced killing of antibiotic-resistant bacteria enabled by massively parallel combinatorial genetics Engineering synthetic TALE and CRISPR/Cas9 transcription factors for regulating gene expression TALEN and CRISPR/Cas Genome Editing Systems: Tools of Discovery.CRISPR-based technologies: prokaryotic defense weapons repurposed A light-inducible CRISPR-Cas9 system for control of endogenous gene activation.Choosing the Right Tool for the Job: RNAi, TALEN, or CRISPR.CRISPR transcriptional repression devices and layered circuits in mammalian cells Principles of genetic circuit design.Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector.Activating human genes with zinc finger proteins, transcription activator-like effectors and CRISPR/Cas9 for gene therapy and regenerative medicine.A CRISPR/Cas9-based system for reprogramming cell lineage specification.Systematic transfer of prokaryotic sensors and circuits to mammalian cells Multi-input CRISPR/Cas genetic circuits that interface host regulatory networks.Target specificity of the CRISPR-Cas9 system.Design and characterization of a dual-mode promoter with activation and repression capability for tuning gene expression in yeast Evaluation of sgRNA target sites for CRISPR-mediated repression of TP53 Rapid prototyping of microbial cell factories via genome-scale engineering.Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators Engineered biosynthesis of natural products in heterologous hosts Quantitative CRISPR interference screens in yeast identify chemical-genetic interactions and new rules for guide RNA design.Synthetic biology: insights into biological computation.Targeted genome regulation via synthetic programmable transcriptional regulators.Distinct patterns of Cas9 mismatch tolerance in vitro and in vivo Digital logic circuits in yeast with CRISPR-dCas9 NOR gates Dissecting the Genetic Basis of a Complex cis-Regulatory Adaptation CRISPR-mediated Activation of Latent HIV-1 Expression Rapid generation of CRISPR/dCas9-regulated, orthogonally repressible hybrid T7-lac promoters for modular, tuneable control of metabolic pathway fluxes in Escherichia coli

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P2860

Tunable and multifunctional eukaryotic transcription factors based on CRISPR/Cas

http://www.wikidata.org/entity/Q24606465

description

2013 nî lūn-bûn

@nan

2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2013年の論文

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2013年論文

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2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

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2013年論文

@zh-tw

2013年论文

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name

Tunable and multifunctional eukaryotic transcription factors based on CRISPR/Cas

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Tunable and multifunctional eukaryotic transcription factors based on CRISPR/Cas

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Tunable and multifunctional eukaryotic transcription factors based on CRISPR/Cas

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type

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Tunable and multifunctional eukaryotic transcription factors based on CRISPR/Cas

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Tunable and multifunctional eukaryotic transcription factors based on CRISPR/Cas

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Tunable and multifunctional eukaryotic transcription factors based on CRISPR/Cas

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prefLabel

Tunable and multifunctional eukaryotic transcription factors based on CRISPR/Cas

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Tunable and multifunctional eukaryotic transcription factors based on CRISPR/Cas

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Tunable and multifunctional eukaryotic transcription factors based on CRISPR/Cas

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ACS Synthetic Biology

P1476

Tunable and multifunctional eukaryotic transcription factors based on CRISPR/Cas

@en

P2093

Fahim Farzadfard

http://www.w3.org/2001/XMLSchema#string

Samuel D Perli

http://www.w3.org/2001/XMLSchema#string

Timothy K Lu

http://www.w3.org/2001/XMLSchema#string

P2860

Stochastic mRNA synthesis in mammalian cells

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

RNA-guided human genome engineering via Cas9

Multiplex genome engineering using CRISPR/Cas systems

Efficient genome editing in zebrafish using a CRISPR-Cas system

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

RNA-guided editing of bacterial genomes using CRISPR-Cas systems

Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems

Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

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604-13

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scholarly article

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1497592

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10.1021/SB400081R

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10

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2

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2013-10-18T00:00:00Z

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263941945

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23977949

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3805333

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