Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans - Wikidata - wikimedia - TriplyDB

Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans

Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans

http://www.wikidata.org/entity/Q24608268

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Ecology and transmission of Buruli ulcer disease: a systematic review Buruli ulcer (M. ulcerans infection): new insights, new hope for disease control.Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones Seasonal and regional dynamics of M. ulcerans transmission in environmental context: deciphering the role of water bugs as hosts and vectors A newly discovered mycobacterial pathogen isolated from laboratory colonies of Xenopus species with lethal infections produces a novel form of mycolactone, the Mycobacterium ulcerans macrolide toxin Globally distributed mycobacterial fish pathogens produce a novel plasmid-encoded toxic macrolide, mycolactone F Evolution of Mycobacterium ulcerans and other mycolactone-producing mycobacteria from a common Mycobacterium marinum progenitor Genomics of Actinobacteria: tracing the evolutionary history of an ancient phylum Inhibitors of Protein Translocation Across the ER Membrane Identification of Ser/Thr kinase and forkhead associated domains in Mycobacterium ulcerans: characterization of novel association between protein kinase Q and MupFHA Structural Studies of an A2-Type Modular Polyketide Synthase Ketoreductase Reveal Features Controlling α-Substituent Stereochemistry Mycobacteriophage and their application to disease control Evolution of polyketide synthases in bacteria Ketoreduction in mycolactone biosynthesis: insight into substrate specificity and stereocontrol from studies of discrete ketoreductase domains in vitro Methodological and Clinical Aspects of the Molecular Epidemiology of Mycobacterium tuberculosis and Other Mycobacteria Development of highly organized lymphoid structures in Buruli ulcer lesions after treatment with rifampicin and streptomycin Detection of Mycolactone A/B in Mycobacterium ulcerans-Infected Human Tissue Comparative genomics analysis of Mycobacterium ulcerans for the identification of putative essential genes and therapeutic candidates The cell wall-associated mycolactone polyketide synthases are necessary but not sufficient for mycolactone biosynthesis Regulation of mycolactone, the Mycobacterium ulcerans toxin, depends on nutrient source Rapid, serial, non-invasive assessment of drug efficacy in mice with autoluminescent Mycobacterium ulcerans infection Analysis of the vaccine potential of plasmid DNA encoding nine mycolactone polyketide synthase domains in Mycobacterium ulcerans infected mice Accelerated detection of mycolactone production and response to antibiotic treatment in a mouse model of Mycobacterium ulcerans disease The pathogenic mechanism of the Mycobacterium ulcerans virulence factor, mycolactone, depends on blockade of protein translocation into the ER The phosphopantetheinyl transferases: catalysis of a post-translational modification crucial for life Computational resources in infectious disease: limitations and challenges Genomic diversity and evolution of Mycobacterium ulcerans revealed by next-generation sequencing Legionella shows a diverse secondary metabolism dependent on a broad spectrum Sfp-type phosphopantetheinyl transferase Spatiotemporal Co-existence of Two Mycobacterium ulcerans Clonal Complexes in the Offin River Valley of Ghana Sticky swinging arm dynamics: studies of an acyl carrier protein domain from the mycolactone polyketide synthase Combinatorial biosynthesis of polyketides--a perspective.Persistent association of Mycobacterium ulcerans with West African predaceous insects of the family belostomatidae Mycolactone gene expression is controlled by strong SigA-like promoters with utility in studies of Mycobacterium ulcerans and buruli ulcer.Genome-guided Investigation of Antibiotic Substances produced by Allosalinactinospora lopnorensis CA15-2(T) from Lop Nor region, China.Gap, a mycobacterial specific integral membrane protein, is required for glycolipid transport to the cell surface.Impact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli ulcer pathogenesis.Detecting the molecular scars of evolution in the Mycobacterium tuberculosis complex by analyzing interrupted coding sequences.Distribution of Mycobacterium ulcerans in buruli ulcer endemic and non-endemic aquatic sites in Ghana Differential gene repertoire in Mycobacterium ulcerans identifies candidate genes for patho-adaptation.Non mycobacterial virulence genes in the genome of the emerging pathogen Mycobacterium abscessus

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Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans

http://www.wikidata.org/entity/Q24608268

description

2004 nî lūn-bûn

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2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2004 թվականի փետրվարին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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Giant plasmid-encoded polyketi ...... oxin of Mycobacterium ulcerans

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Giant plasmid-encoded polyketi ...... oxin of Mycobacterium ulcerans

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Giant plasmid-encoded polyketi ...... oxin of Mycobacterium ulcerans

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Giant plasmid-encoded polyketi ...... oxin of Mycobacterium ulcerans

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Giant plasmid-encoded polyketi ...... oxin of Mycobacterium ulcerans

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Giant plasmid-encoded polyketi ...... oxin of Mycobacterium ulcerans

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Proceedings of the National Academy of Sciences of the United States of America

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Giant plasmid-encoded polyketi ...... oxin of Mycobacterium ulcerans

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Armand Mve-Obiang

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Grant A Jenkin

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John K Davies

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Melinda J Pryor

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Pamela L C Small

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Paul D R Johnson

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Sarojini Adusumilli

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Stephen F Haydock

http://www.w3.org/2001/XMLSchema#string

Stewart T Cole

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Thierry Garnier

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P2860

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

Aquatic insects as a vector for Mycobacterium ulcerans.

Identification and characterization of IS2404 and IS2606: two distinct repeated sequences for detection of Mycobacterium ulcerans by PCR

Common themes in microbial pathogenicity revisited

The structure of docking domains in modular polyketide synthases

Polyketide synthesis: prospects for hybrid antibiotics

Mycolactone: a polyketide toxin from Mycobacterium ulcerans required for virulence

Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling

Use of a Mycobacterium tuberculosis H37Rv bacterial artificial chromosome library for genome mapping, sequencing, and comparative genomics.

The FHA domain.

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scholarly article

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10.1073/PNAS.0305877101

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5

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101

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Peter Francis Leadlay

Timothy Stinear

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2004-02-03T00:00:00Z

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8908371

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14736915

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Mycobacterium ulcerans

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337055

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