A ceramide-binding C1 domain mediates kinase suppressor of ras membrane translocation
about
VRK2 anchors KSR1-MEK1 to endoplasmic reticulum forming a macromolecular complex that compartmentalizes MAPK signalingKSR1 is a functional protein kinase capable of serine autophosphorylation and direct phosphorylation of MEK1Regulation of protein kinases by lipidsSphingolipid signaling in metabolic disordersRe-configuration of sphingolipid metabolism by oncogenic transformation.DC-SIGN mediated sphingomyelinase-activation and ceramide generation is essential for enhancement of viral uptake in dendritic cellsKdo2-lipid A, a TLR4-specific agonist, induces de novo sphingolipid biosynthesis in RAW264.7 macrophages, which is essential for induction of autophagyLaurdan monitors different lipids content in eukaryotic membrane during embryonic neural development.Ceramide-rich platforms in transmembrane signaling.Proteome-wide Identification of Novel Ceramide-binding Proteins by Yeast Surface cDNA Display and Deep SequencingIt's a lipid's world: bioactive lipid metabolism and signaling in neural stem cell differentiation.Two protein kinase C isoforms, δ and ε, regulate energy homeostasis in mitochondria by transmitting opposing signals to the pyruvate dehydrogenase complex.Ceramide limits phosphatidylinositol-3-kinase C2β-controlled cell motility in ovarian cancer: potential of ceramide as a metastasis-suppressor lipidMembrane signaling induced by high doses of ionizing radiation in the endothelial compartment. Relevance in radiation toxicity.Sphingolipids in neurodegeneration.Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance.Roles for biological membranes in regulating human immunodeficiency virus replication and progress in the development of HIV therapeutics that target lipid metabolism.Ceramide formation as a target in beta-cell survival and function.Regulation of metabolism and transport of sphingosine-1-phosphate in mammalian cells.Sphingolipid abnormalities in cancer multidrug resistance: Chicken or egg?Kinase suppressor of Ras transphosphorylates c-Raf-1.Ceramide in stem cell differentiation and embryo development: novel functions of a topological cell-signaling lipid and the concept of ceramide compartments.Protein kinase CK2 associates to lipid rafts and its pharmacological inhibition enhances neurotransmitter release.C-ceramide is a natural regulatory ligand of p53 in cellular stress response
P2860
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P2860
A ceramide-binding C1 domain mediates kinase suppressor of ras membrane translocation
description
2009 nî lūn-bûn
@nan
2009 թուականին հրատարակուած գիտական յօդուած
@hyw
2009 թվականին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
A ceramide-binding C1 domain mediates kinase suppressor of ras membrane translocation
@ast
A ceramide-binding C1 domain mediates kinase suppressor of ras membrane translocation
@en
A ceramide-binding C1 domain mediates kinase suppressor of ras membrane translocation
@nl
type
label
A ceramide-binding C1 domain mediates kinase suppressor of ras membrane translocation
@ast
A ceramide-binding C1 domain mediates kinase suppressor of ras membrane translocation
@en
A ceramide-binding C1 domain mediates kinase suppressor of ras membrane translocation
@nl
prefLabel
A ceramide-binding C1 domain mediates kinase suppressor of ras membrane translocation
@ast
A ceramide-binding C1 domain mediates kinase suppressor of ras membrane translocation
@en
A ceramide-binding C1 domain mediates kinase suppressor of ras membrane translocation
@nl
P2093
P2860
P356
P1476
A ceramide-binding C1 domain mediates kinase suppressor of ras membrane translocation
@en
P2093
Hyunmi Lee
Mohammad Zafrullah
Richard Kolesnick
Xianglei Yin
P2860
P304
P356
10.1159/000233248
P407
P577
2009-01-01T00:00:00Z