The testosterone-derived neurosteroid androstanediol is a positive allosteric modulator of GABAA receptors
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Neurosteroids and GABA(A) Receptor Interactions: A Focus on StressCatamenial Epilepsy: Discovery of an Extrasynaptic Molecular Mechanism for Targeted TherapyNeurosteroids and their role in sex-specific epilepsiesAtomic Force Microscopy Protocol for Measurement of Membrane Plasticity and Extracellular Interactions in Single Neurons in EpilepsySex differences in social investigation: effects of androgen receptors, hormones and test partner.Inhibition of 17α-hydroxylase/C17,20 lyase reduces gating deficits consequent to dopaminergic activation.High serum androstenedione levels correlate with impaired memory in the surgically menopausal rat: a replication and new findings.Neurosteroids and GABAergic signaling in health and diseaseDutasteride reduces alcohol's sedative effects in men in a human laboratory setting and reduces drinking in the natural environmentPerimenstrual-like hormonal regulation of extrasynaptic δ-containing GABAA receptors mediating tonic inhibition and neurosteroid sensitivity.Animal models of absence epilepsies: what do they model and do sex and sex hormones matter?11β-Hydroxylase inhibitors protect against seizures in mice by increasing endogenous neurosteroid synthesis.Role of anticonvulsant and antiepileptogenic neurosteroids in the pathophysiology and treatment of epilepsy.Reduced Chrna7 expression in mice is associated with decreases in hippocampal markers of inhibitory function: implications for neuropsychiatric diseases.Neo-synthesis of estrogenic or androgenic neurosteroids determine whether long-term potentiation or depression is induced in hippocampus of male rat.Neuroendocrine aspects of catamenial epilepsyThe 5α-reductase inhibitor finasteride is not associated with alterations in sleep spindles in men referred for polysomnography.Anger Emotional Stress Influences VEGF/VEGFR2 and Its Induced PI3K/AKT/mTOR Signaling Pathway.Anxiolytic-like Effect of Testosterone in Male Rats: GABAC Receptors Are Not InvolvedThe brain, seizures and epilepsy throughout life: understanding a moving target.Neurosteroid Structure-Activity Relationships for Functional Activation of Extrasynaptic δGABA(A) Receptors.Estrous cycle regulation of extrasynaptic δ-containing GABA(A) receptor-mediated tonic inhibition and limbic epileptogenesisTestosterone depletion in adult male rats increases mossy fiber transmission, LTP, and sprouting in area CA3 of hippocampusRole of hormones and neurosteroids in epileptogenesis.Zinc Selectively Blocks Neurosteroid-Sensitive Extrasynaptic δGABAA Receptors in the Hippocampus.Neurosteroid interactions with synaptic and extrasynaptic GABA(A) receptors: regulation of subunit plasticity, phasic and tonic inhibition, and neuronal network excitability.Sex differences in the anticonvulsant activity of neurosteroidsSex differences in anxiety and depression: role of testosteroneClinical Potential of Neurosteroids for CNS Disorders.Modulatory role of androgenic and estrogenic neurosteroids in determining the direction of synaptic plasticity in the CA1 hippocampal region of male rats.Calming Down During Coming of Age.Programming the brain and behaviour by early-life stress: a focus on neuroactive steroids.Neurosteroids for the potential protection of humans against organophosphate toxicity.Novel therapeutic approaches for disease-modification of epileptogenesis for curing epilepsy.Effects of combined IUGR and prenatal stress on the development of the hippocampus in a fetal guinea pig model.Impact of anger emotional stress before pregnancy on adult male offspring.Glial source of nitric oxide in epileptogenesis: A target for disease modification in epilepsy.Genetic and Molecular Regulation of Extrasynaptic GABA-A Receptors in the Brain: Therapeutic Insights for Epilepsy.SSRIs and the female brain--potential for utilizing steroid-stimulating properties to treat menstrual cycle-linked dysphorias.Testosterone potentiates the hypoxic ventilatory response of adult male rats subjected to neonatal stress.
P2860
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P2860
The testosterone-derived neurosteroid androstanediol is a positive allosteric modulator of GABAA receptors
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The testosterone-derived neuro ...... c modulator of GABAA receptors
@ast
The testosterone-derived neuro ...... c modulator of GABAA receptors
@en
The testosterone-derived neuro ...... c modulator of GABAA receptors
@nl
type
label
The testosterone-derived neuro ...... c modulator of GABAA receptors
@ast
The testosterone-derived neuro ...... c modulator of GABAA receptors
@en
The testosterone-derived neuro ...... c modulator of GABAA receptors
@nl
prefLabel
The testosterone-derived neuro ...... c modulator of GABAA receptors
@ast
The testosterone-derived neuro ...... c modulator of GABAA receptors
@en
The testosterone-derived neuro ...... c modulator of GABAA receptors
@nl
P2860
P3181
P356
P1476
The testosterone-derived neuro ...... c modulator of GABAA receptors
@en
P2093
Kuihuan Jian
P2860
P304
P3181
P356
10.1124/JPET.110.169854
P407
P50
P577
2010-06-15T00:00:00Z